Article
Environmental Sciences
Nadeem Hussain Solangi, Nabisab Mujawar Mubarak, Rama Rao Karri, Shaukat Ali Mazari, Abdul Sattar Jatoi
Summary: In recent years, electroanalysis has made significant progress, particularly in the development of electrochemical sensors. These sensors include photoelectrochemical and electro-chemiluminescence sensors, which combine optical techniques with traditional electrochemical bio/non-biosensors. Various methods have been designed for commercial applications to detect biological and non-biological markers for different diseases. The study extensively discusses MXene-based electrochemical sensors, photoelectrochemical sensors, enzyme-based biosensors, immunosensors, aptasensors, electro-chemiluminescence sensors, and electrochemical non-biosensors, highlighting their performance in detecting various substances and contaminants, as well as the challenges and prospects for MXene-based electrochemical sensors.
ENVIRONMENTAL RESEARCH
(2023)
Article
Chemistry, Analytical
Wenting Wu, Jing Li
Summary: Nanozymes, as emerging artificial enzymes, have attracted attention in the sensing field due to their superior catalytic properties and high stability. Nanozyme-based electrochemical sensing has experienced fast growth, providing high sensitivity, selectivity, ease of miniaturization, and versatile signal reporting modes. This article discusses representative works in the field, focusing on different signal reporting manners, such as traditional electrochemical assays, electrochemiluminescent, and photoelectrochemical sensing. Furthermore, the current challenges and future perspectives are also addressed.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2023)
Review
Biochemical Research Methods
Minu Mathew, Sithara Radhakrishnan, Antara Vaidyanathan, Brahmananda Chakraborty, Chandra Sekhar Rout
Summary: The research interest in wearable sensors, particularly in electrochemical biosensors based on two-dimensional nanomaterials, has significantly increased in recent years. The use of flexible conductive platforms for the development of wearable electrochemical biosensors offers new opportunities to monitor biologically relevant molecules in real-time. These advancements have the potential to revolutionize healthcare monitoring and clinical analysis.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Review
Chemistry, Analytical
Rong Wu, Zhe Feng, Jingjing Zhang, Liping Jiang, Jun-Jie Zhu
Summary: This article reviews the application of quantum dots in electrochemical cell analysis. It introduces the electrochemical and photophysical characteristics of quantum dots, and critically reviews their application in electrochemical cell analysis from the aspects of components, mechanism, and principle. The article also summarizes the research on quantum dot-based electrochemical cytosensors from 2017 to 2021, and discusses the detection abilities for different targets.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
P. K. Kalambate, P. Thirabowonkitphithan, P. Kaewarsa, K. Permpoka, A. B. Radwan, R. A. Shakoor, R. P. Kalambate, H. Khosropour, Y. Huang, W. Laiwattanapaisal
Summary: Advances in nanotechnology have led to the use of various nanomaterials as electrode materials for electrochemical sensors and biosensors. Two-dimensional layered materials (2DLMs) are gaining popularity due to their unique structure and properties. This review provides a comprehensive summary of the development and applications of 2DLMs and their composites in electrochemical sensors and biosensors, as well as their potential use in food safety, environmental monitoring, and clinical analysis.
MATERIALS TODAY CHEMISTRY
(2022)
Article
Chemistry, Analytical
Lun Wang, Huixin Zhang, Tingting Zhuang, Jingxu Liu, Neso Sojic, Zonghua Wang
Summary: The study demonstrates the enhancement of ECL signals by precise control of the sensing interface using two-dimensional transition metal carbides. A highly sensitive and selective ECL biosensor was developed, with a wide linear detection range, for the detection of PNK and screening of its inhibitors. The practicality of the method was tested in MCF-7 cell lysate, promising future applications of Ti3C2Tx materials in the ECL bioanalysis field.
ANALYTICA CHIMICA ACTA
(2022)
Review
Chemistry, Analytical
Jian Zhang, Xiaoyue Zhang, Sai Bi
Summary: This article discusses the categories, properties, and synthetic routes of two-dimensional quantum dots (2D-QDs) based on different materials, and emphasizes their applications in electrochemical biosensors.
Article
Chemistry, Multidisciplinary
Huanhuan Shi, Panpan Zhang, Zaichun Liu, SangWook Park, Martin R. Lohe, Yuping Wu, Ali Shaygan Nia, Sheng Yang, Xinliang Feng
Summary: The study demonstrated a fluoride-free, iodine-assisted etching route for preparing oxygen-rich two-dimensional MXene with intact lattice structure. These MXene sheets exhibit excellent thin-film conductivity and great ambient stability in water, showing promise for practical applications.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Review
Chemistry, Multidisciplinary
Muhammad Atif Khan, Faizan Ramzan, Muhammad Ali, Muhammad Zubair, Muhammad Qasim Mehmood, Yehia Massoud
Summary: Two-dimensional materials (2DMs) have been extensively studied in the field of electrochemical sensors, with a particular focus on those directly related to human life and health. In this overview, we have explored the applications of 2DMs-based electrochemical sensors, such as graphene and its derivatives, transition metal dichalcogenide, and MXenes, in detecting glucose in human blood, nitrates and nitrites, as well as pesticides. We believe that the discussed areas are of great importance, and our summary of prominent reports in these areas can provide guidance for the future evolution of electrochemical sensors.
Article
Chemistry, Multidisciplinary
Siowwoon Ng, Jiri Sturala, Jan Vyskocil, Petr Lazar, Jana Martincova, Jan Plutnar, Martin Pumera
Summary: This study investigates the functionalization of germananes for targeted tuning of their properties for photo- and electrochemical energy conversion applications. It was found that the performance of functionalized germananes is influenced by the different functional groups attached, with some showing lower overpotentials in the hydrogen evolution reaction and higher photocurrent densities for water oxidation. These findings highlight the potential for organic functionalization of 2D germananes for various energy conversion applications.
Review
Chemistry, Analytical
Tao Li, Dawei Shang, Shouwu Gao, Bo Wang, Hao Kong, Guozheng Yang, Weidong Shu, Peilong Xu, Gang Wei
Summary: This review discusses the recent advances in fabrication of 2DM-based electrochemical sensors and biosensors for applications in food safety and biomolecular detection related to human health. It includes the synthesis methods, structure, and surface chemistry of various 2DMs, as well as their applications in detecting nitrite, heavy metal ions, antibiotics, pesticides, and key small molecules for disease monitoring.
Review
Chemistry, Analytical
Selva Bilge, Ali Sinag
Summary: This study explores the role of MXenes in photoelectrochemical applications and discusses in depth the effect of MXenes on photoelectrochemical sensing processes. The review also covers the latest trends, current research, and new strategies in MXene-based photoelectrochemical sensors/biosensors. Additionally, the study provides a detailed examination of the synthesis of MXenes with a green approach and their integration into photoelectrochemical sensing/biosensing applications for the first time.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Engineering, Environmental
Siowwoon Ng, Kalyan Ghosh, Jan Vyskocil, Martin Pumera
Summary: Modern wearable electronics require scalable, flexible, and conductive electrodes with tunable properties. This study combines flexible graphite films and 2D vanadium sulfide to achieve multiple functionalities such as photoelectrocatalysis and pseudocapacitive charge storage.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Zhiquan He, Tengda Rong, Yan Li, Junjie Ma, Quanshui Li, Furong Wu, Yuhang Wang, Fengping Wang
Summary: In this study, a facile synthesis method for bimetallic solid-solution MXene was reported, and its application in SERS detection was investigated. A free-standing film was prepared as the substrate, and a SERS enhancement factor of 10^12 and a femtomolar-level detection limit were achieved. The results indicated that the SERS activity of the TiVC-analyte system was dominated by the chemical mechanism (CM). This work provides guidance for the synthesis of 2D MXene and its application in ultrasensitive SERS detection.
Article
Green & Sustainable Science & Technology
Y. Zhang, Z. Feng, X. Wang, H. Hu, M. Wu
Summary: Due to their excellent electrical conductivity and water processibility, MXenes have been widely used as an important promoter to boost the electrochemical capability of many energy storage and conversion materials. Carbon materials represent one of the most prevalent components to combine with MXenes for improved electrochemical performance. This review summarizes the latest progress in the controllable fabrication of MXene/carbon composites for electrochemical energy storage and conversion, including their usage in lithium storage, sodium storage, lithium-sulfur batteries, supercapacitors, and electrocatalysis.
MATERIALS TODAY SUSTAINABILITY
(2023)
Article
Chemistry, Analytical
Yanxiao Jiang, Bo Zhang, Jingkang Li, Ying Sun, Xinghua Wang, Pinyi Ma, Daqian Song
Summary: A novel vortex-assisted solid-phase extraction method was developed for the determination of parabens in water samples. The method combined the preparation of sponge column materials with high performance liquid chromatography analysis, successfully detecting four parabens in different water samples with low limits of detection and high accuracy.
Article
Biochemical Research Methods
Dan Li, Fangfang Chen, Na Li, Xiwen Ye, Ying Sun, Pinyi Ma, Daqian Song, Xinghua Wang
Summary: A new type of fluorescent silicon nanoparticles was prepared via a one-pot hydrothermal method for constructing a ratiometric fluorescence assay, allowing rapid and sensitive determination of xanthine in human serum. The assay demonstrated superior sensitivity and reduced testing time compared to traditional methods, showing potential for future fabrication of novel fluorescent probes for detecting biological metabolites involved in H2O2-generation or consumption reactions.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Yanxiao Jiang, Xu Li, Huilan Piao, Zucheng Qin, Jingkang Li, Ying Sun, Xinghua Wang, Pinyi Ma, Daqian Song
Summary: Metal-organic framework-melamine foam columns were developed for the extraction of triazine herbicides from vegetable oil samples, showing low detection limits and favorable relative standard deviations under optimal conditions.
JOURNAL OF SEPARATION SCIENCE
(2021)
Article
Chemistry, Analytical
Huilan Piao, Yanxiao Jiang, Zucheng Qin, Pinyi Ma, Ying Sun, Xinghua Wang, Daqian Song, Qiang Fei
Summary: A novel magnetic deep eutectic solvent was developed for the determination of triazine herbicides in rice, offering advantages of rapid, convenient, sensitive, and cost-effective analysis. The solvent simplified extraction and separation procedures and showed satisfactory precision, accuracy, matrix effect, and robustness, indicating its suitability for rice sample analysis.
Article
Chemistry, Analytical
Xiaowei Mu, Minxing Wu, Bo Zhang, Xin Liu, Shaomei Xu, Yibing Huang, Xinghua Wang, Daqian Song, Pinyi Ma, Ying Sun
Summary: A fluorescent probe based on the combination of carbon dots and silver nanoparticles was developed for sensitive and selective detection of cysteamine. The probe showed a detection range of 2-16 μM with a detection limit of 0.35 μM, and high recovery rates in spiked bovine serum samples. Additionally, the probe had low cytotoxicity and was successfully used for in vivo imaging of HepG2 cells.
Article
Biochemical Research Methods
Yanxiao Jiang, Zucheng Qin, Fanghui Liang, Jingkang Li, Ying Sun, Xinghua Wang, Pinyi Ma, Daqian Song
Summary: In this study, a sorbent material for trace determination of six triazine herbicides in water samples was successfully prepared by embedding MIL-101(Cr) and chitosan directly into the skeleton of melamine sponge material.
JOURNAL OF CHROMATOGRAPHY A
(2021)
Article
Biochemical Research Methods
Xueqi Zhao, Yue Zhang, Xinghua Wang, Pinyi Ma, Daqian Song, Ying Sun
Summary: In this study, a LRSPR biosensor was developed using PDA/Ti3C2-MXene/PDA-gold film as the sensing substrate and AuNPs as enhancers. The biosensor demonstrated excellent performance with a broad detection range and low detection limit.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Biochemical Research Methods
Wei Zhang, Yu Zhang, Xin Liu, Yue Zhang, Yibing Liu, Wei Wang, Rui Su, Ying Sun, Yibing Huang, Daqian Song, Yanhua Wu, Xinghua Wang
Summary: A sensing platform with both ratiometric fluorescence and colorimetric responses towards copper(II) ions and D-penicillamine was developed based on carbon dots. The platform exhibited excellent selectivity and sensitivity, and showed potential for live cell imaging.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Biochemical Research Methods
Xiwen Ye, Yanxiao Jiang, Xiaowei Mu, Ying Sun, Pinyi Ma, Ping Ren, Daqian Song
Summary: A highly sensitive fluorescence-based assay for cholesterol detection was developed using water-dispersible green-emitting silicon nanoparticles (SiNPs) as a fluorescence indicator and enzyme-catalyzed oxidation product PPDox as a quencher. The established ultrasensitive fluorescent assay accurately measured cholesterol with a low limit of detection and a wide linear range, and demonstrated good accuracy in detecting real samples.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Li Jingkang, Jiang Yanxiao, Yang Jukun, Sun Ying, Ma Pinyi, Song Daqian
Summary: A novel environmental-friendly composite absorbent material was designed and prepared in this study. The material showed excellent adsorption performance and stable reusability. It was characterized using high performance liquid chromatography and other analytical techniques, and successfully applied for the solid phase extraction of pollutants from water samples.
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
(2022)
Article
Chemistry, Analytical
Yibing Liu, Xue Jiang, Wei Wang, Wei Zhang, Xinghua Wang, Ying Sun, Yibing Huang, Pinyi Ma, Daqian Song
Summary: In this study, a multifunctional probe was developed for bimodal imaging of glutathione (GSH) by improving stability and targeted recognition capability. The probe showed good magnetic resonance imaging (MRI) contrast agent and near-infrared emission properties, making it a promising tool in biological detection.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Haohua Yang, Xueqi Zhao, Ziwei Zhang, Pinyi Ma, Xinghua Wang, Daqian Song, Ying Sun
Summary: This paper presents a sensitive SPR biosensor based on ZnO@Au nanomaterial for the detection of hIgG. The biosensor utilizes a sandwich strategy using biotin-streptavidin for secondary signal amplification. With optimal experimental conditions, the biosensor achieves a favorable concentration range of 0.0375-40 μg/mL for hIgG determination, which is approximately 67 times lower than conventional gold film-based SPR sensors.
Article
Chemistry, Analytical
Lanlan Xu, Hongyu Chu, Dejiang Gao, Qiong Wu, Ying Sun, Zhenxin Wang, Pinyi Ma, Daqian Song
Summary: Fluorescence imaging-guided diagnostics is a promising method for detecting tumors in situ due to its simplicity and non-invasiveness. The chemosensor LAN-beta gal, with a specific recognition unit of d-galactose residue and a fluorophore of LAN-OH, showed remarkable fluorescence enhancement after beta-gal was digested. It successfully visualized endogenous beta-gal, distinguished ovarian cancer cells from normal cells, and was applied in vivo for tumor detection and surgical resection of ovarian cancer. The LAN-beta gal chemosensor shows potential as a new tool for the clinical diagnosis and treatment of ovarian cancer.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Wei Wang, Jingkang Li, Yibing Liu, Wei Zhang, Ying Sun, Pinyi Ma, Daqian Song
Summary: Alkaline phosphatase (ALP) is a widely present and important biomarker in the human body. Researchers synthesized a core-shell metal-organic framework sensor that can be used for sensitive and accurate ALP detection. By self-triggered control of phosphate ions (Pi), the sensor avoids the potential inaccuracy caused by using ascorbic acid (AA) as the reducing component. The developed strategy has shown linear response to ALP concentrations ranging from 0.1 to 150 mU/mL with a detection limit of 0.03 mU/mL.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Zhang Yue, Zhang Wei, Wang Xing-Hua, Ma Pin-Yi, Sun Ying, Song Da-Qian
Summary: A detection system based on g-C3N4 nanosheets, copper ions, and o-phenylenediamine (OPD) was developed for the detection of Coenzyme A (CoA). The system showed good sensitivity and selectivity with a proportional fluorescence response to CoA concentration. This method has the potential for detecting CoA in complex biological matrices.
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
(2022)