Integrated analysis of physiological, transcriptomics and metabolomics provides insights into detoxication disruption of PFOA exposure in Mytilus edulis

CPT1A-mediated Fat Oxidation, Mechanisms, and Therapeutic Potential

(2020) Isabel R Schlaepfer et al.   ENDOCRINOLOGY

Pathway-based assessment of single chemicals and mixtures by a high-throughput transcriptomics approach

(2020) Pu Xia et al.   ENVIRONMENT INTERNATIONAL

Metabolomic and transcriptomic profiling reveals the alteration of energy metabolism in oyster larvae during initial shell formation and under experimental ocean acidification

(2020) Zhaoqun Liu et al.   Scientific Reports

Persulfate-based degradation of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) in aqueous solution: Review on influences, mechanisms and prospective

(2020) Lie Yang et al.   JOURNAL OF HAZARDOUS MATERIALS

Distribution of perfluorinated alkyl substances in marine shellfish along the Chinese Bohai Sea coast

(2019) Mengmeng Guo et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES

Integrated application of transcriptomics and metabolomics provides insights into unsynchronized growth in pearl oyster Pinctada fucata martensii

(2019) Ruijuan Hao et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Insights into the uptake, elimination and accumulation of microplastics in mussel

(2019) Beatriz Fernández et al.   ENVIRONMENTAL POLLUTION

The Effect of Persistent Heavy Metal Exposure on Some Antioxidant Enzyme Activities and Lipid Peroxidation of the Freshwater snail, Lymnaea natalensis

(2019) S. M. Mnkandla et al.   BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Stress response and tolerance mechanisms of ammonia exposure based on transcriptomics and metabolomics in Litopenaeus vannamei

(2019) Jie Xiao et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Antioxidant defenses and metabolic responses of blue mussels (Mytilus edulis) exposed to various concentrations of erythromycin

(2019) Ruoyu Liang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Molecular mechanism of CAT and SOD activity change under MPA-CdTe quantum dots induced oxidative stress in the mouse primary hepatocytes

(2019) Minglu Hao et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

High-throughput sequencing of the transcriptome and chromatin accessibility in the same cell

(2019) Song Chen et al.   NATURE BIOTECHNOLOGY

Adverse effects of perfluoroalkyl acids on fish and other aquatic organisms: a review

(2019) Jin Wuk Lee et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Nrf2a modulates the embryonic antioxidant response to perfluorooctanesulfonic acid (PFOS) in the zebrafish, Danio rerio

(2018) Karilyn E. Sant et al.   AQUATIC TOXICOLOGY

Effects to perfluorooctane sulfonate (PFOS) on the mollusk Unio ravoisieri under laboratory exposure

(2018) Imen Amraoui et al.   CHEMISTRY AND ECOLOGY

Transcriptomic approach: A promising tool for rapid screening nanomaterial-mediated toxicity in the marine bivalve Mytilus edulis —Application to copper oxide nanoparticles

(2018) Amélie Châtel et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer

(2018) Xiu‐Fei Chen et al.   EMBO REPORTS

Role of the Nrf2-ARE pathway in perfluorooctanoic acid (PFOA)-induced hepatotoxicity in Rana nigromaculata

(2018) Juan Tang et al.   ENVIRONMENTAL POLLUTION

Transcriptomic and Network Analyses Reveal Mechanistic-Based Biomarkers of Endocrine Disruption in the Marine Mussel, Mytilus edulis

(2018) Bonnie J. Blalock et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Mitochondrial β-oxidation of saturated fatty acids in humans

(2018) María M. Adeva-Andany et al.   MITOCHONDRION

Use of high-throughput in vitro toxicity screening data in cancer hazard evaluations by IARC Monograph Working Groups

(2018) Weihsueh Chiu   ALTEX-Alternatives to Animal Experimentation

Gene Expression Is Altered in Piglet Small Intestine by Weaning and Dietary Glutamine Supplementation

(2018) Junjun Wang et al.   JOURNAL OF NUTRITION

Metal bioaccumulation and detoxification processes in cephalopods: A review

(2017) Virginie Penicaud et al.   ENVIRONMENTAL RESEARCH

Molecular Mechanisms of Developmental Toxicity Induced by Graphene Oxide at Predicted Environmental Concentrations

(2017) Xingli Zhang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Effects of chronic perfluorooctanoic acid (PFOA) at low concentration on morphometrics, gene expression, and fecundity in zebrafish ( Danio rerio )

(2017) Carrie E. Jantzen et al.   REPRODUCTIVE TOXICOLOGY

Effect of single-wall carbon nanotubes on bioconcentration and toxicity of perfluorooctane sulfonate in zebrafish ( Danio rerio )

(2017) Yaxuan Li et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Chronic perfluorooctane sulfonate (PFOS) exposure induces hepatic steatosis in zebrafish

(2016) Jiangfei Cheng et al.   AQUATIC TOXICOLOGY

Chronic perfluorooctanesulfonic acid exposure disrupts lipid metabolism in zebrafish

(2016) Y Cui et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Pyruvate kinase deletion as an effective phenotype to enhance lysine production in Corynebacterium glutamicum ATCC13032: Redirecting the carbon flow to a precursor metabolite

(2016) Masaki Yanase et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Human xanthine oxidase recombinant in E. coli: A whole cell catalyst for preparative drug metabolite synthesis

(2016) Márcia Ferreira Antunes et al.   JOURNAL OF BIOTECHNOLOGY

Effects of Fatty Acids on Intracellular [Ca2+], Mitochondrial Uncoupling and Apoptosis in Rat Pachytene Spermatocytes and Round Spermatids

(2016) Joaquín Paillamanque et al.   PLoS One

Multigenerational effect of perfluorooctane sulfonate (PFOS) on the individual fitness and population growth of Daphnia magna

(2016) Tae-Yong Jeong et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis

(2015) Yu Sun et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Ecotoxicological impact of engineered nanomaterials in bivalve molluscs: An overview

(2015) Thiago Lopes Rocha et al.   MARINE ENVIRONMENTAL RESEARCH

Microplastics in bivalves cultured for human consumption

(2014) Lisbeth Van Cauwenberghe et al.   ENVIRONMENTAL POLLUTION

Fate and effects of poly- and perfluoroalkyl substances in the aquatic environment: A review

(2014) Lutz Ahrens et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Curcumin Induced Human Gastric Cancer BGC-823 Cells Apoptosis by ROS-Mediated ASK1-MKK4-JNK Stress Signaling Pathway

(2014) Tao Liang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cholesterol biosynthesis and ER stress in peroxisome deficiency

(2013) Phyllis L. Faust et al.   BIOCHIMIE

Mechanistic toxicity study of perfluorooctanoic acid in zebrafish suggests mitochondrial dysfunction to play a key role in PFOA toxicity

(2013) A. Hagenaars et al.   CHEMOSPHERE

Induction of oxidative stress and related transcriptional effects of perfluorononanoic acid using an in vivo assessment

(2013) Shaoli Yang et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Marine ecosystem health status assessment through integrative biomarker indices: a comparative study after the Prestige oil spill “Mussel Watch”

(2013) Ionan Marigómez et al.   ECOTOXICOLOGY

Acetyl-l-carnitine supplementation reverses the age-related decline in carnitine palmitoyltransferase 1 (CPT1) activity in interfibrillar mitochondria without changing the l-carnitine content in the rat heart

(2012) Luis A. Gómez et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Translational responses and oxidative stress of mussels experimentally exposed to Hg, Cu and Cd: One pattern does not fit at all

(2011) Sofia Pytharopoulou et al.   AQUATIC TOXICOLOGY

Lipid peroxidation and oxidative stress responses of salmon fed a diet containing perfluorooctane sulfonic- or perfluorooctane carboxylic acids

(2011) Augustine Arukwe et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Adaptation of freshwater mussels to cyanobacterial toxins: Response of the biotransformation and antioxidant enzymes

(2011) Vanessa Burmester et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Retrospective Exposure Estimation and Predicted versus Observed Serum Perfluorooctanoic Acid Concentrations for Participants in the C8 Health Project

(2011) Hyeong-Moo Shin et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The bottleneck of JNK signaling: Molecular and functional characteristics of MKK4 and MKK7

(2011) Wiebke Haeusgen et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Unsaturated Fatty Acids Drive Disintegrin and Metalloproteinase (ADAM)-dependent Cell Adhesion, Proliferation, and Migration by Modulating Membrane Fluidity

(2011) Karina Reiss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Full-length transcriptome assembly from RNA-Seq data without a reference genome

(2011) Manfred G Grabherr et al.   NATURE BIOTECHNOLOGY

High-sensitivity c-reactive protein and gamma-glutamyl transferase levels are synergistically associated with metabolic syndrome in community-dwelling persons

(2010) Ryuichi Kawamoto et al.   Cardiovascular Diabetology

Perfluorooctanoic acid induces peroxisomal fatty acid oxidation and cytokine expression in the liver of male Japanese medaka (Oryzias latipes)

(2010) Jae-Ho Yang   CHEMOSPHERE

The Role of Nrf2 and MAPK Pathways in PFOS-Induced Oxidative Stress in Zebrafish Embryos

(2010) Xiongjie Shi et al.   TOXICOLOGICAL SCIENCES

Role of PPAR in Hepatic Carbohydrate Metabolism

(2010) Annelies Peeters et al.   PPAR Research

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Rate of Decline in Serum PFOA Concentrations after Granular Activated Carbon Filtration at Two Public Water Systems in Ohio and West Virginia

(2009) Scott M. Bartell et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Perfluoroalkyl sulfonic and carboxylic acids: A critical review of physicochemical properties, levels and patterns in waters and wastewaters, and treatment methods

(2009) Sierra Rayne et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING

Induction of time-dependent oxidative stress and related transcriptional effects of perfluorododecanoic acid in zebrafish liver

(2008) Y LIU et al.   AQUATIC TOXICOLOGY

Genomic Profiling Reveals an Alternate Mechanism for Hepatic Tumor Promotion by Perfluorooctanoic Acid in Rainbow Trout

(2008) Susan C. Tilton et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Glutathione: Overview of its protective roles, measurement, and biosynthesis

(2008) Henry Jay Forman et al.   MOLECULAR ASPECTS OF MEDICINE