Exploiting Transient Radical Cations as Bronsted Acids for Allylic C-H Heteroarylation of Enol Silyl Ethers

Intermediary radical cations, generated through single-electron oxidation of enol silyl ethers by excited Ir-based photocatalysts, can be exploited as Bronsted acids for the activation of heteroarylcyanides. This strategy enables the direct allylic C-H heteroarylation of enol silyl ethers under visible-light irradiation.

Automated summary

Intermediary radical cations, generated through single-electron oxidation of enol silyl ethers by excited Ir-based photocatalysts, are exploited as Bronsted acids for activating heteroarylcyanides. This enables the direct allylic C-H heteroarylation of enol silyl ethers under visible-light irradiation.