Article
Biochemistry & Molecular Biology
Martin Kellert, Jan-Simon Jeshua Friedrichs, Nadine Anke Ullrich, Alexander Feinhals, Jonas Tepper, Peter Loennecke, Evamarie Hey-Hawkins
Summary: The development of novel boron-rich compounds for use in boron neutron capture therapy (BNCT) is an important field in cancer treatment. The study reports the design and synthesis of two promising compounds that combine meta-carborane, a water-soluble monosaccharide, and a linking unit for coupling with tumor-selective biomolecules. This approach enables the development of readily obtainable boron-rich agents with optimized properties for potential applications in BNCT.
Article
Chemistry, Multidisciplinary
Anna Chandrasekar Murali, Prakash Nayak, Shashwat Nayak, Sabyasachi Das, Satyaprasad P. Senanayak, Krishnan Venkatasubbaiah
Summary: The development of new n-type semiconductors with tunable band gap and dielectric constant is important for high-performance optoelectronic devices. Boron-beta-thioketonates (MTDKB), which are analogues to boron-beta-diketonates containing a sulfur atom, were synthesized. The MTDKBs exhibited outstanding bulk electron mobility and single junction photo responsivity. They also showed luminescent properties and were investigated as fluorescent sensors with amine functionality.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Biochemistry & Molecular Biology
Vaclav Mik, Tomas Pospisil, Federica Brunoni, Jiri Gruz, Vladimfra Nozkova, Claus Wasternack, Otto Miersch, Miroslav Strnad, Kristyna Flokova, Ondrej Novak, Jitka Siroka
Summary: This research presents a highly sensitive method for the reliable determination of seven OPDA-aa compounds in plants. The method was optimized for extraction, sample clean-up, and final analysis. Five endogenous (+)-OPDA-aa were identified and their levels were estimated in mechanically wounded Arabidopsis thaliana leaves, with a peak observed 60 minutes after the wounding. The synthetic and analytical methodologies developed in this study will contribute to the understanding of the biological significance of these metabolites in plants.
Review
Chemistry, Multidisciplinary
Hai-Yan He, Haruka Niikura, Yi-Ling Du, Katherine S. Ryan
Summary: This review summarizes synthetic and biosynthetic approaches to diverse nitrogen-nitrogen-bond-containing functional groups, with a focus on biosynthetic pathways and enzymes.
CHEMICAL SOCIETY REVIEWS
(2022)
Review
Chemistry, Multidisciplinary
Seokho Moon, Jiye Kim, Jeonghyeon Park, Semi Im, Jawon Kim, Inyong Hwang, Jong kyu Kim
Summary: Hexagonal boron nitride (h-BN) is attracting significant interest due to its extraordinary properties in optoelectronics, quantum optics, and electronics. It can be used as an ideal substrate and insulating layer for other 2D materials, and has potential applications in emerging electronics and photonics fields.
ADVANCED MATERIALS
(2023)
Review
Biochemistry & Molecular Biology
Natallia V. Dubashynskaya, Anton N. Bokatyi, Yury A. Skorik
Summary: Dexamethasone, a commonly prescribed glucocorticoid, shows a wide spectrum of pharmacological activity. Conjugating it to polymeric carriers helps reduce side effects on non-target organs and achieve controlled release in various target organs, making it potentially effective for anti-tumor therapy.
Review
Chemistry, Multidisciplinary
Jia Zhang, Biying Tan, Xin Zhang, Feng Gao, Yunxia Hu, Lifeng Wang, Xiaoming Duan, Zhihua Yang, PingAn Hu
Summary: Atomically thin hexagonal boron nitride (h-BN) is a promising 2D material with unique properties for applications in optoelectronics and electronics. Chemical vapor deposition (CVD) is considered a promising method for producing large-scale, high-quality h-BN films and heterostructures. The epitaxial growth of 2D materials onto h-BN and building heterostructures can lead to novel properties.
ADVANCED MATERIALS
(2021)
Article
Polymer Science
Juliana A. S. Montenegro, Andreas Ries, Ingridy D. S. Silva, Carlos B. B. Luna, Antonia L. Souza, Renate M. R. Wellen
Summary: In this study, both synthetic and enzymatic routes were investigated for the epoxidation of castor oil to reduce environmental impact. Fourier transform infrared spectroscopy (FTIR) and nuclear magnetic resonance in hydrogen molecules (H-1-NMR) were used to analyze the reactions. The results showed that the enzymatic reactions (6 h) and synthetic reactions achieved conversion rates of 50-96% and epoxidation rates of 25-48%. It was also observed that the absence of a solid catalyst resulted in a selectivity of 2% and the presence of solid catalysts (Amberlite and lipase enzyme) was crucial for the conversion of castor oil into oxirane rings.
Review
Chemistry, Physical
Aida Chelagha, Dan Louvel, Alexis Taponard, Rodolphe Berthelon, Anis Tlili
Summary: This mini-review aims to explore the various methodologies for accessing arylsulfonyl fluorides, which include a diverse range of starting materials and conditions such as with or without a catalyst.
Review
Chemistry, Multidisciplinary
Sjoerd Slagman, Wolf-Dieter Fessner
Summary: The lack of effective anti-viral therapies has once again been highlighted by recent outbreaks of COVID-19 and Ebola. Biocatalysis offers sustainable and environmentally friendly synthetic strategies for producing pharmaceuticals, including FDA-approved anti-viral drugs. There is still potential for the development of novel synthetic routes using biocatalytic methods to aid in mass production of future treatments for COVID-19.
CHEMICAL SOCIETY REVIEWS
(2021)
Review
Chemistry, Organic
Federico Nicoli, Massimo Baroncini, Serena Silvi, Jessica Groppi, Alberto Credi
Summary: Crown ethers are macrocyclic hosts that can complex a wide range of species, and their direct functionalization has been underexplored but can offer advantages in reducing synthetic effort and allowing for later modifications. Methods for direct functionalization of aliphatic and aromatic crown ethers have been sporadically reported in the literature over the past four decades, providing new ways to exploit these versatile macrocycles in contemporary supramolecular science and technology.
ORGANIC CHEMISTRY FRONTIERS
(2021)
Article
Pharmacology & Pharmacy
Hsuan-Ping Chang, Huyen Khanh Le, Dhaval K. K. Shah
Summary: We hypothesized that different routes of administration may have an impact on the PK/PD behavior of ADCs and help improve their therapeutic index. To test this hypothesis, we evaluated the PK/PD of an ADC administered via subcutaneous (SC) and intratumoral (IT) routes. Our findings showed that IT administration significantly increased tumor exposure and anti-tumor activity of the ADC. The PK/PD model suggested that the IT route could provide similar efficacy as the IV route at a reduced dose level and increased dosing interval, while SC administration led to local toxicity and reduced efficacy.
Article
Chemistry, Physical
Junjie Jiang, Constantine Tsounis, Leighanne C. Gallington, Yongfeng Hu, Robert W. J. Scott, Jason A. Scott, Nicholas M. Bedford
Summary: Metal oxide nanomaterials synthesized using a biomineralization-inspired method have been shown to have increased surface area and controllable catalytic properties. The use of protamine as a protein template resulted in largely disordered materials with changes in atomic structure dependent on synthetic conditions. Removal of protamine and subsequent hydrogenation induced defects in the materials while retaining their disordered nature, showing potential for controlling catalytic properties using benign synthetic strategies.
ACS APPLIED ENERGY MATERIALS
(2021)
Article
Chemistry, Physical
Meng Yang, Hui Jin, Zejun Sun, Rijun Gui
Summary: This review provides a systematic summary of experimental preparation methods, functionalized modification strategies, and practical applications of 2D boron-based nanomaterials and their derivatives. It covers a wide range of topics including preparation methods, functionalization strategies, and potential applications. The review is timely, comprehensive, and highly valuable for scientists from multiple disciplines and scientific fields.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Mirela Petruta Suchea, Evangelia Petromichelaki, Cosmin Romanitan, Maria Androulidaki, Alexandra Manousaki, Zacharias Viskadourakis, Rabia Ikram, Petronela Pascariu, George Kenanakis
Summary: This study examined the use of common beverages as reagents for synthesizing ZnO coatings in place of expensive high purity reagents, resulting in nanostructured ZnO coatings with good optical properties. The research provides insights into the surface structuring of ZnO coatings and the potential for utilizing non-toxic beverages in optoelectronic applications.
Article
Chemistry, Multidisciplinary
Devulapally Koteshwar, Seelam Prasanthkumar, Surya Prakash Singh, Towhid H. Chowdhury, Idriss Bedja, Ashraful Islam, Lingamallu Giribabu
Summary: A series of newly designed porphyrin sensitizers were studied for their photovoltaic performance, with those containing the cyanoacrylic acid anchoring group showing higher efficiency. Compared to LG18, sensitizers LG24 and LG26 with conjugated electron acceptors have advantages in terms of spectra and electronic structure.
MATERIALS CHEMISTRY FRONTIERS
(2022)
Article
Materials Science, Multidisciplinary
Chinmoy Biswas, Siva Gangadhar Palivela, Lingamallu Giribabu, Venugopal Rao Soma, Sai Santosh Kumar Raavi
Summary: In this study, the ethynylthiophene functionalized porphyrin molecule LG5 was comprehensively characterized for its optical and non-linear optical properties. The results suggest that LG5 has great potential for application in organic solar cell devices and exhibits good photosensitizer performance and efficient electron injection in dye-sensitized solar cells.
Review
Energy & Fuels
Kalavala Shivaprakash Srivishnu, Prasutha Rani Markapudi, Senthilarasu Sundaram, Lingamallu Giribabu
Summary: Perovskite solar cells technology is advanced and fascinating due to its low-cost processing and efficient power conversion efficiencies. Researchers have been exploiting the transparency of perovskite solar cells to meet environmental and energy needs. Placing semitransparent perovskite solar cells on windows and rooftops of buildings can reduce room temperature and fulfill power requirements.
Article
Biochemical Research Methods
Siva Hariprasad Kurma, Ramya Somanaboina, Lakshmi Reddy Vanammoole, K. S. Srivishnu, China Raju Bhimapaka, Lingamallu Giribabu
Summary: Here, the authors reported the synthesis of 2H-pyrano[3,2-c]chromene-2,5(6H)-diones 3a-x by reacting 4-hydroxycoumarins 1a-b with Baylis-Hillman adducts 2a-w. The optical and electrochemical properties of these compounds were studied, revealing that the electron releasing and electron withdrawing groups had minimal impact on the electronic behavior of the pyranochromene moiety. The compounds showed thermal stability up to 200°C and emitted blue or green light, making them potential candidates for OLEDs.
JOURNAL OF FLUORESCENCE
(2023)
Article
Chemistry, Physical
Chinmoy Biswas, Palivela Siva Gangadhar, Lingamallu Giribabu, Prabhakar Chetti, Dipanjan Banerjee, Venugopal Rao Soma, Sai Santosh Kumar Raavi
Summary: This study presents a comprehensive investigation of the ultrafast photophysical properties and charge injection dynamics of phenothiazine-functionalized push-pull Zinc porphyrin adsorbed on mesoporous TiO2. The impact of acceptor units on charge injection times is revealed, and the nonlinear optical properties of the porphyrin are characterized. The findings suggest strong potential for optical limiting and optical signal processing applications.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2022)
Article
Chemistry, Physical
Md Soif Ahmed, Chinmoy Biswas, Botta Bhavani, Seelam Prasanthkumar, Dipanjan Banerjee, Vipin Kumar, Prabhakar Chetti, Lingamallu Giribabu, Venugopal Rao Soma, Sai Santosh Kumar Raavi
Summary: This study investigates the photophysical characterization of four porphyrin compounds in solution using transient absorption spectroscopy, and validates the experimental results through nonlinear optical properties and theoretical calculations.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Ushasri Chilakamarthi, Namita S. Mahadik, Devulapally Koteshwar, Narra Vamsi Krishna, Lingamallu Giribabu, Rajkumar Banerjee
Summary: Photodynamic therapy (PDT) combined with chemotherapy shows potential as a non-invasive treatment for cancer. In this study, we used novel porphyrin-based photosensitizers in combination with low dose doxorubicin (Dox) to enhance the therapeutic outcome. Our results demonstrate that Dox synergizes with PDT to inhibit tumor growth in vitro, but there is still a possibility of relapse due to chemoresistance and immune suppression.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Gangada Suneel, Kanika Jain, Boligorla Anjaiah, Hrishit Mitra, Ramya Athira Ramnagar, Srikanth Bandi, Vijaykumar Chuncha, Tapta Kanchan Roy, Lingamallu Giribabu, Raghu Chitta
Summary: The N, N-bis (4'-tert-butylbiphenyl-4-yl)aniline tethered zinc porphyrins have been synthesized and photosynthetic antenna-reaction center models were constructed via co-ordination with fulleropyrrolidines. The study showed the occurrence of photoinduced energy transfer and electron transfer, resulting in the formation of charge-separated supramolecular complexes.
JOURNAL OF PORPHYRINS AND PHTHALOCYANINES
(2022)
Article
Chemistry, Multidisciplinary
Boligorla Anjaiah, Manne Naga Rajesh, Lingamallu Giribabu, Raghu Chitta
Summary: Panchromatic azaborondipyrromethenes connected with TPA and Naph were synthesized and their roles in photo-induced energy and electron transfer processes were investigated. Optical absorption studies showed that integrating naphthalene and TPA moieties into the azaBODIPY core resulted in broad-band capturing dyes. Electrochemical studies revealed that TPA was easier to oxidize, consistent with its role as an electron donor in PET processes. Fluorescence studies indicated PET and PEnT processes occurring in nanosecond time scales.
CHEMISTRY-AN ASIAN JOURNAL
(2023)
Article
Engineering, Electrical & Electronic
Madarapu Naresh, Palivela Siva Gangadhar, Priti Kumari, Nagadatta Pravallika, Yelukala Ramakrishna, Lingamallu Giribabu, Seelam Prasanthkumar
Summary: Tuning the crystallinity in self-assembled nanostructures hasa significant impact on the electronic properties. In this research, three symmetric freebase and metallo substituted porphyrin appended bispyridylquinoxalines (P-Fb-DPQ, P-Cu-DPQ andP(Zn)-DPQ) were developed, and copper metalated P-DPQ exhibited crystalline phase transitions under light stimuli. Light stimulation regulated the morphology from 0D nanosphere to 2D nanosheets in P-Cu-DPQ and H+[P-Cu-DPQ(Cl)](-), promoting the amorphous to crystalline nature.
ACS APPLIED ELECTRONIC MATERIALS
(2023)
Article
Chemistry, Physical
Swathi Nenavath, Naresh Duvva, Ram R. R. Kaswan, Gary N. N. Lim, Francis D'Souza, Lingamallu Giribabu
Summary: Donor phenanthroimidazole (PhI) is directly connected to a BODIPY acceptor (Dyad1) through an ethynyl bridge (Dyad2). Spectroscopic and electrochemical analysis suggests minimal π-π interaction between PhI and BODIPY. The dyads exhibit quenched emission when excited at absorption maxima of PhI or BODIPY, indicating intramolecular photoinduced excitation energy transfer and electron transfer. The dyads also generate charge-separated species and have high energy transfer rate constants, making them useful for light energy harvesting applications.
JOURNAL OF PHYSICAL CHEMISTRY A
(2023)
Article
Engineering, Electrical & Electronic
Parnapalli Muni Mounika, Meenakshamma Ambapuram, Gurulakshmi Maddala, Susmitha Kalvapalli, Mukhesh K. Ganesha, Ashutosh K. Singh, Narayana Thota, Manne Naga Rajesh, Lingamallu Giribabu, Katta Venkateswarlu, Raghavender Mitty
Summary: A bifacial tandem dye-sensitized solar cell (DSSC-DSSC) with LG6 and N719 dyes integrated has been developed, exhibiting a high solar power conversion efficiency and stable performance. This work opens up a pioneering research approach for bifacial tandem solar cells with the DSSC.
ACS APPLIED ELECTRONIC MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Md Soif Ahmed, Kalavala Shivaprakash Srivishnu, Chinmoy Biswas, Dipanjan Banerjee, Prabhakar Chetti, Venugopal Rao Soma, Lingamallu Giribabu, Sai Santosh Kumar Raavi
Summary: Metal-substituted phthalocyanines exhibit diverse structures and excellent optoelectronic properties, and their photophysical properties were comprehensively investigated in this study. Femtosecond transient absorption spectroscopy was used to study the excited-state relaxation dynamics of newly synthesized metal-free and metallated phthalocyanines. The nonlinear optical phenomena of these compounds were explored through the analysis of lifetime values obtained from the spectroscopy data and the fitting of nonlinear refractive indices and second hyperpolarizabilities calculated using DFT calculations. Enhancement of the nonlinear characteristics was observed for the metallated phthalocyanines compared to the metal-free ones. The findings provide insights into the critical variables involved in their optoelectronic properties.
MATERIALS ADVANCES
(2023)
Article
Chemistry, Multidisciplinary
Anjaiah Boligorla, Manne Naga Rajesh, Lingamallu Giribabu, Raghu Chitta
Summary: A dual-dye integrated polyaromatic azaborondipyrromethene was synthesized and its role as an electron and energy relay in the photoinduced process was investigated.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Deepak Badgurjar, Naresh Duvva, Anirban Bagui, Pooja, Sapna Gahlot, Ravinder Pawar, Surya Prakash Singh, Ashish Garg, Lingamallu Giribabu, Raghu Chitta
Summary: A series of phenothiazine-C-60/70 dyads were synthesized and their light-induced electron transfer events were explored. The donor and acceptor moieties in the dyads showed no electronic communication in the ground state, but their emission intensity was quenched in the presence of polar solvents. The emission quenching was attributed to intramolecular photo-induced electron transfer. The dyads exhibited higher efficiency in solar cell devices.
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
(2022)