Reactivation of the Hedgehog pathway in esophageal progenitors turns on an embryonic-like program to initiate columnar metaplasia
出版年份 2021 全文链接
标题
Reactivation of the Hedgehog pathway in esophageal progenitors turns on an embryonic-like program to initiate columnar metaplasia
作者
关键词
cell plasticity, dedifferentiation, transdifferentiation, transcommitment, metaplasia, Barrett’s esophagus, reprogramming, progenitors
出版物
Cell Stem Cell
Volume -, Issue -, Pages -
出版商
Elsevier BV
发表日期
2021-04-21
DOI
10.1016/j.stem.2021.03.019
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- GeneSwitches: Ordering gene-expression and functional events in single-cell experiments
- (2020) Elaine Y Cao et al. BIOINFORMATICS
- Comprehensive Integration of Single-Cell Data
- (2019) Tim Stuart et al. CELL
- Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics
- (2018) Kelly Street et al. BMC GENOMICS
- YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration
- (2018) Shiro Yui et al. Cell Stem Cell
- Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche
- (2018) Ysbrand M. Nusse et al. NATURE
- Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance
- (2018) Piyush B. Gupta et al. Cell Stem Cell
- Diallyl Disulfide Suppresses the Inflammation and Apoptosis Resistance Induced by DCA Through ROS and the NF-κB Signaling Pathway in Human Barrett’s Epithelial Cells
- (2017) Cheng Feng et al. INFLAMMATION
- Single-cell transcriptomics reconstructs fate conversion from fibroblast to cardiomyocyte
- (2017) Ziqing Liu et al. NATURE
- Transitional basal cells at the squamous–columnar junction generate Barrett’s oesophagus
- (2017) Ming Jiang et al. NATURE
- Normalizing single-cell RNA sequencing data: challenges and opportunities
- (2017) Catalina A Vallejos et al. NATURE METHODS
- From Reflux Esophagitis to Esophageal Adenocarcinoma
- (2016) Rhonda F. Souza DIGESTIVE DISEASES
- Mid-Esophagus Columnar Metaplasia: What Is the Biopathogenic Pathway?
- (2016) Inês Rolim et al. INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY
- Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq
- (2016) Barbara Treutlein et al. NATURE
- Molecular features of cellular reprogramming and development
- (2016) Zachary D. Smith et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Adult cell plasticity in vivo: de-differentiation and transdifferentiation are back in style
- (2016) Allyson J. Merrell et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update
- (2016) Enis Afgan et al. NUCLEIC ACIDS RESEARCH
- Genetic and Epigenetic Alterations in Barrett’s Esophagus and Esophageal Adenocarcinoma
- (2015) Andrew M. Kaz et al. GASTROENTEROLOGY CLINICS OF NORTH AMERICA
- Dissection of keratin network formation, turnover and reorganization in living murine embryos
- (2015) Nicole Schwarz et al. Scientific Reports
- Cox2 and β-Catenin/T-cell Factor Signaling Intestinalize Human Esophageal Keratinocytes When Cultured under Organotypic Conditions
- (2015) Jianping Kong et al. NEOPLASIA
- HTSeq--a Python framework to work with high-throughput sequencing data
- (2014) S. Anders et al. BIOINFORMATICS
- Trimmomatic: a flexible trimmer for Illumina sequence data
- (2014) Anthony M. Bolger et al. BIOINFORMATICS
- Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett’s metaplasia
- (2014) David H. Wang et al. JOURNAL OF CLINICAL INVESTIGATION
- The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells
- (2014) Cole Trapnell et al. NATURE BIOTECHNOLOGY
- deepTools: a flexible platform for exploring deep-sequencing data
- (2014) Fidel Ramírez et al. NUCLEIC ACIDS RESEARCH
- Global Changes in Gene Expression of Barrett's Esophagus Compared to Normal Squamous Esophagus and Gastric Cardia Tissues
- (2014) Paula L. Hyland et al. PLoS One
- Cellular Heterogeneity in the Mouse Esophagus Implicates the Presence of a Nonquiescent Epithelial Stem Cell Population
- (2014) Aaron D. DeWard et al. Cell Reports
- PAVIS: a tool for Peak Annotation and Visualization
- (2013) Weichun Huang et al. BIOINFORMATICS
- Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
- (2013) Jason D Buenrostro et al. NATURE METHODS
- Sox9 drives columnar differentiation of esophageal squamous epithelium: a possible role in the pathogenesis of Barrett's esophagus
- (2012) Nicholas J. Clemons et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Bile Acid and Inflammation Activate Gastric Cardia Stem Cells in a Mouse Model of Barrett-Like Metaplasia
- (2012) Michael Quante et al. CANCER CELL
- Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase
- (2012) Yosef Buganim et al. CELL
- Barrett's Esophagus: Is the Goblet Half Empty?
- (2012) Stuart Jon Spechler Clinical Gastroenterology and Hepatology
- Hedgehog signalling stimulates precursor cell accumulation and impairs epithelial maturation in the murine oesophagus
- (2012) Willemijn A van Dop et al. GUT
- Activation of Wnt signalling promotes development of dysplasia in Barrett's oesophagus
- (2012) Lisa H Moyes et al. JOURNAL OF PATHOLOGY
- Adult interfollicular tumour-initiating cells are reprogrammed into an embryonic hair follicle progenitor-like fate during basal cell carcinoma initiation
- (2012) Khalil Kass Youssef et al. NATURE CELL BIOLOGY
- Fast gapped-read alignment with Bowtie 2
- (2012) Ben Langmead et al. NATURE METHODS
- Evidence for a functional role of epigenetically regulated midcluster HOXB genes in the development of Barrett esophagus
- (2012) M. di Pietro et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Single Progenitor Population Switches Behavior to Maintain and Repair Esophageal Epithelium
- (2012) D. P. Doupe et al. SCIENCE
- Residual Embryonic Cells as Precursors of a Barrett's-like Metaplasia
- (2011) Xia Wang et al. CELL
- DNA methylation profiling in Barrett’s esophagus and esophageal adenocarcinoma reveals unique methylation signatures and molecular subclasses
- (2011) Andrew M. Kaz et al. Epigenetics
- Integrative genomics viewer
- (2011) James T Robinson et al. NATURE BIOTECHNOLOGY
- ChIP-seq reveals cell type-specific binding patterns of BMP-specific Smads and a novel binding motif
- (2011) Masato Morikawa et al. NUCLEIC ACIDS RESEARCH
- Ectopic Cdx2 Expression in Murine Esophagus Models an Intermediate Stage in the Emergence of Barrett's Esophagus
- (2011) Jianping Kong et al. PLoS One
- Barx1-Mediated Inhibition of Wnt Signaling in the Mouse Thoracic Foregut Controls Tracheo-Esophageal Septation and Epithelial Differentiation
- (2011) Janghee Woo et al. PLoS One
- Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors
- (2010) Masaki Ieda et al. CELL
- BMP signaling in the development of the mouse esophagus and forestomach
- (2010) P. Rodriguez et al. DEVELOPMENT
- Aberrant Epithelial–Mesenchymal Hedgehog Signaling Characterizes Barrett's Metaplasia
- (2010) David H. Wang et al. GASTROENTEROLOGY
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- Primary contribution to zebrafish heart regeneration by gata4 + cardiomyocytes
- (2010) Kazu Kikuchi et al. NATURE
- Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation
- (2010) Chris Jopling et al. NATURE
- Direct conversion of fibroblasts to functional neurons by defined factors
- (2010) Thomas Vierbuchen et al. NATURE
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Cells keep a memory of their tissue origin during axolotl limb regeneration
- (2009) Martin Kragl et al. NATURE
- Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity
- (2009) Ashwin Woodhoo et al. NATURE NEUROSCIENCE
- Novel signals controlling embryonic Schwann cell development, myelination and dedifferentiation
- (2008) Rhona Mirsky et al. JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM
- Cdx1 and c-Myc Foster the Initiation of Transdifferentiation of the Normal Esophageal Squamous Epithelium toward Barrett's Esophagus
- (2008) Douglas B. Stairs et al. PLoS One
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started