The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr

Purified Smc5/6 Complex Exhibits DNA Substrate Recognition and Compaction

(2020) Pilar Gutierrez-Escribano et al.   MOLECULAR CELL

The Smc5/6 Core Complex Is a Structure-Specific DNA Binding and Compacting Machine

(2020) Diego Serrano et al.   MOLECULAR CELL

Promiscuous Targeting of Cellular Proteins by Vpr Drives Systems-Level Proteomic Remodeling in HIV-1 Infection

(2019) Edward J.D. Greenwood et al.   Cell Reports

Functional proteomic atlas of HIV infection in primary human CD4+ T cells

(2019) Adi Naamati et al.   eLife

Unintegrated HIV-1 DNAs are loaded with core and linker histones and transcriptionally silenced

(2019) Franziska K. Geis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human cohesin compacts DNA by loop extrusion

(2019) Yoori Kim et al.   SCIENCE

ATACseqQC: a Bioconductor package for post-alignment quality assessment of ATAC-seq data

(2018) Jianhong Ou et al.   BMC GENOMICS

Smc5/6 Antagonism by HBx Is an Evolutionarily Conserved Function of Hepatitis B Virus Infection in Mammals

(2018) Fabien Abdul et al.   JOURNAL OF VIROLOGY

Episomal HIV-1 DNA and its relationship to other markers of HIV-1 persistence

(2018) Javier Martinez-Picado et al.   Retrovirology

Acute Smc5/6 depletion reveals its primary role in rDNA replication by restraining recombination at fork pausing sites

(2018) Xiao P. Peng et al.   PLoS Genetics

The Smc5/6 Complex: New and Old Functions of the Enigmatic Long-Distance Relative

(2018) Luis Aragón   Annual Review of Genetics

Towards a Unified Model of SMC Complex Function

(2018) Markus Hassler et al.   CURRENT BIOLOGY

Brc1 Promotes the Focal Accumulation and SUMO Ligase Activity of Smc5-Smc6 during Replication Stress

(2018) Martina Oravcová et al.   MOLECULAR AND CELLULAR BIOLOGY

NP220 mediates silencing of unintegrated retroviral DNA

(2018) Yiping Zhu et al.   NATURE

Quantitative Temporal Viromics of an Inducible HIV-1 Model Yields Insight to Global Host Targets and Phospho-Dynamics Associated with Protein Vpr

(2017) John D. Lapek et al.   MOLECULAR & CELLULAR PROTEOMICS

The condensin complex is a mechanochemical motor that translocates along DNA

(2017) Tsuyoshi Terakawa et al.   SCIENCE

Multiplex single-cell visualization of nucleic acids and protein during HIV infection

(2017) Maritza Puray-Chavez et al.   Nature Communications

Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens

(2017) David W. Morgens et al.   Nature Communications

Distribution and fate of HIV-1 unintegrated DNA species: a comprehensive update

(2017) Faysal Bin Hamid et al.   AIDS Research and Therapy

Histones Are Rapidly Loaded onto Unintegrated Retroviral DNAs Soon after Nuclear Entry

(2016) Gary Z. Wang et al.   Cell Host & Microbe

The Evolutionary Histories of Antiretroviral Proteins SERINC3 and SERINC5 Do Not Support an Evolutionary Arms Race in Primates

(2016) Ben Murrell et al.   JOURNAL OF VIROLOGY

Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor

(2016) Adrien Decorsière et al.   NATURE

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

(2016) John G Doench et al.   NATURE BIOTECHNOLOGY

HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages

(2016) Hichem Lahouassa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV-1 and HIV-2 exhibit divergent interactions with HLTF and UNG2 DNA repair proteins

(2016) Kasia Hrecka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatitis B Virus X Protein Promotes Degradation of SMC5/6 to Enhance HBV Replication

(2016) Christopher M. Murphy et al.   Cell Reports

Smc5/6 Is a Telomere-Associated Complex that Regulates Sir4 Binding and TPE

(2016) Sarah Moradi-Fard et al.   PLoS Genetics

Temporal proteomic analysis of HIV infection reveals remodelling of the host phosphoproteome by lentiviral Vif variants

(2016) Edward JD Greenwood et al.   eLife

Sambamba: fast processing of NGS alignment formats

(2015) Artem Tarasov et al.   BIOINFORMATICS

Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef

(2015) Nicholas J. Matheson et al.   Cell Host & Microbe

Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells

(2015) I. A. Tchasovnikarova et al.   SCIENCE

Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links

(2015) M. Raschle et al.   SCIENCE

Gene essentiality and synthetic lethality in haploid human cells

(2015) V. A. Blomen et al.   SCIENCE

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

Quantitative analysis of the time-course of viral DNA forms during the HIV-1 life cycle

(2013) Soundasse Munir et al.   Retrovirology

Genetic Screens in Human Cells Using the CRISPR-Cas9 System

(2013) Tim Wang et al.   SCIENCE

HIV 2-long terminal repeat circular DNA is stable in primary CD4+T Cells

(2013) Matthew J. Pace et al.   VIROLOGY

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

Hepatitis B virus X protein stimulates gene expression selectively from extrachromosomal DNA templates

(2012) Pieter C. van Breugel et al.   HEPATOLOGY

Tandem Protein Interaction Modules Organize the Ubiquitin-Dependent Response to DNA Double-Strand Breaks

(2012) Stephanie Panier et al.   MOLECULAR CELL

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

RNAscope

(2011) Fay Wang et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Extrachromosomal Circular DNA in Eukaryotes: Possible Involvement in the Plasticity of Tandem Repeats

(2009) S. Cohen et al.   CYTOGENETIC AND GENOME RESEARCH