期刊
BRITISH JOURNAL OF CANCER
卷 125, 期 2, 页码 149-151出版社
SPRINGERNATURE
DOI: 10.1038/s41416-021-01315-y
关键词
-
类别
Inhibiting the chemokine receptor CXCR4 suppresses intratumoral immune reaction, providing insights into the role of CXCR4 in cancer immunoediting.
A recent Phase 1 clinical study of the immunological effects of inhibiting the chemokine receptor, CXCR4, in patients with pancreatic ductal adenocarcinoma or colorectal cancer suggests that stimulation of CXCR4 on immune cells suppresses the intratumoural immune reaction. Here, we discuss how CXCR4 mediates this response, and how cancer cells elicit it.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据