Spinal astrocyte aldehyde dehydrogenase-2 mediates ethanol metabolism and analgesia in mice

Alcohol-aggravated episodic pain in humans with SCN11A mutation and ALDH2 polymorphism

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Spinal GABAA receptors for pain control: back to the future?

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Pharmacological mechanisms of alcohol analgesic-like properties in mouse models of acute and chronic pain

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Targeting liver aldehyde dehydrogenase-2 prevents heavy but not moderate alcohol drinking

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Control of motor coordination by astrocytic tonic GABA release through modulation of excitation/inhibition balance in cerebellum

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Aldehyde dehydrogenase 2 overexpression inhibits neuronal apoptosis after spinal cord ischemia/reperfusion injury

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Nicotine Enhances the Hypnotic and Hypothermic Effects of Alcohol in the Mouse

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Aldehyde dehydrogenase 1a1 mediates a GABA synthesis pathway in midbrain dopaminergic neurons

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Glial GABA, synthesized by monoamine oxidase B, mediates tonic inhibition

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Targeting Aldehyde Dehydrogenase 2: New Therapeutic Opportunities

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Aldehyde dehydrogenase-2 regulates nociception in rodent models of acute inflammatory pain

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GABAB receptor ligands for the treatment of alcohol use disorder: preclinical and clinical evidence

(2014) Roberta Agabio et al.   Frontiers in Neuroscience

Differential effects of ethanol on regional glutamatergic and GABAergic neurotransmitter pathways in mouse brain

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Metabolic products of [2-13C]ethanol in the rat brain after chronic ethanol exposure

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Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel

(2013) Ludovic Sauguet et al.   Nature Communications

Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors

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Alcohol dependence as a chronic pain disorder

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GABA release by hippocampal astrocytes

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GABA and central neuropathic pain following spinal cord injury

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Extrasynaptic GABAA receptors in the nucleus accumbens are necessary for alcohol drinking

(2011) R. W. Olsen   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ethanol-enhanced GABA release: A focus on G protein-coupled receptors

(2010) M. Katherine Kelm et al.   BRAIN RESEARCH REVIEWS

Molecular comparison of GLT1+ and ALDH1L1+ astrocytes in vivo in astroglial reporter mice

(2010) Yongjie Yang et al.   GLIA

Channel-Mediated Tonic GABA Release from Glia

(2010) S. Lee et al.   SCIENCE

Increased pain sensitivity in alcohol withdrawal syndrome

(2009) Thomas Jochum et al.   EUROPEAN JOURNAL OF PAIN

Acetate transport and utilization in the rat brain

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Reversal of pathological pain through specific spinal GABAA receptor subtypes

(2008) Julia Knabl et al.   NATURE

Ethanol's Molecular Targets

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