Article
Environmental Sciences
Maya Negev, Yara Dahdal, Haneen Khreis, Assaf Hochman, Mohammed Shaheen, Madi T. A. Jaghbir, Pinhas Alpert, Hagai Levine, Nadav Davidovitch
Summary: This paper discusses the COVID-19 outbreak in Israel, Palestine, and Jordan, emphasizing the potential for cross-border infections and outbreaks transmission. It highlights Jordan's ability to better contain the virus and calls for strengthened health surveillance and cross-border cooperation to protect the health of all inhabitants in the region.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Biophysics
Fevzi Altuntas, Naim Ata, Tugce Nur Yigenoglu, Semih Basci, Mehmet Sinan Dal, Serdal Korkmaz, Sinem Namdaroglu, Abdulkadir Basturk, Tuba Hacibekiroglu, Mehmet Hilmi Dogu, Ilhami Berber, Kursat Dal, Mehmet Ali Erkurt, Burhan Turgut, Mustafa Mahir Ulgu, Osman Celik, Abdullah Akunal, Suayip Birinci
Summary: This study reports the outcomes of COVID-19 in hematopoietic cell transplant recipients, showing a higher case fatality rate in these patients, particularly among those receiving immunosuppressive agents.
BONE MARROW TRANSPLANTATION
(2021)
Review
Medicine, General & Internal
Abdul Rahman Bizri, Nadine Al Akoury, Thulani Mhlanga, Graciela del Carmen Morales, Hammam Haridy, Gregory D. Hussey, Amit Srivastava
Summary: The experience of Africa and the Middle East with the COVID-19 pandemic has been unique due to disparities within these regions. A global approach to vaccination is required for effective control of COVID-19. However, vaccine inequities exist in Africa and the Middle East, with better healthcare infrastructure countries having advantages in vaccine acquisition and delivery. The greatest challenges to COVID-19 vaccination in these regions are funding, healthcare resources, infrastructure, and vaccine access and hesitancy.
ANNALS OF MEDICINE
(2023)
Article
Urology & Nephrology
Ozgur Akin Oto, Savas Ozturk, Mustafa Arici, Arzu Velioglu, Belda Dursun, Nurana Guller, Idris Sahin, Zeynep Ebru Eser, Saime Paydas, Sinan Trabulus, Sumeyra Koyuncu, Murathan Uyar, Zeynep Ural, Rezzan Eren Sadioglu, Hamad Dheir, Neriman Sila Koc, Hakan Ozer, Beyza Algul Durak, Cuma Bulent Gul, Umut Kasapoglu, Ebru Gok Oguz, Mehmet Tanrisev, Gulsah Sasak Kuzgun, Safak Mirioglu, Erkan Dervisoglu, Ertugrul Erken, Numan Gorgulu, Sultan Ozkurt, Zeki Aydin, ilhan Kurultak, Melike Betul Ogutmen, Serkan Bakirdogen, Burcu Kaya, Serhat Karadag, Memnune Sena Ulu, Ozkan Gungor, Elif Ari Bakir, Ali Riza Odabas, Nurhan Seyahi, Alaattin Yildiz, Kenan Ates
Summary: This study evaluated the clinical outcomes of kidney transplant recipients recovering from COVID-19 for 3 months and compared them with a control group. The results showed an increased prevalence of ongoing respiratory symptoms in the first 3 months post-recovery, but no significant difference in mortality.
CLINICAL KIDNEY JOURNAL
(2022)
Article
Pediatrics
Fabian J. S. van der Velden, Frederik van Delft, Stephen Owens, Judit Llevadias, Michael McKean, Lindsey Pulford, Yusri Taha, Grace Williamson, Quentin Campbell-Hewson, Sophie Hambleton, Rebecca Payne, Christopher Duncan, Catriona Johnston, Jarmila Spegarova, Marieke Emonts
Summary: In general, SARS-CoV-2 infection in children, including immunocompromised children, tends to be mild. However, a small percentage of pediatric patients may develop severe respiratory failure and require intensive care treatment.
FRONTIERS IN PEDIATRICS
(2022)
Article
Public, Environmental & Occupational Health
Louise Fawcett
Summary: This paper reviews the impact of COVID-19 on the MENA region, discusses the variable performance of states and institutions in response to the pandemic, and highlights the deficits in regional governance structures along with opportunities for collective action.
GLOBALIZATION AND HEALTH
(2021)
Review
Medicine, General & Internal
Filippo Antonacci, Matteo Petroncini, Elena Salvaterra, Pietro Bertoglio, Niccolo Daddi, Giulia Lai, Jury Brandolini, Piergiorgio Solli, Giampiero Dolci
Summary: Although the WHO has declared the end of the pandemic emergency, COVID-19 still poses a significant threat to immunocompromised patients, especially lung transplant recipients. Two compelling case studies highlight the unpredictable and detrimental course of the disease in these patients, emphasizing the urgent need for increased vigilance and tailored management strategies.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Surgery
Jonathan Miller, Grace R. Lyden, David Zaun, Bertram L. Kasiske, Ryutaro Hirose, Ajay K. Israni, Jon J. Snyder
Summary: Potential regional variations in the effects of COVID-19 on federally mandated, program-specific evaluations by the Scientific Registry of Transplant Recipients (SRTR) have been controversial. This study examined the impact of COVID-19 cases and deaths on posttransplant outcomes and found that the results were highly correlated with or without certain data exclusions. The study also concluded that the geographic impact of these data exclusions was minimal.
AMERICAN JOURNAL OF TRANSPLANTATION
(2022)
Article
Multidisciplinary Sciences
Eleanor C. Stokes, Miguel O. Roman
Summary: In response to the COVID-19 pandemic, governments around the world have implemented physical distancing measures. However, there is limited information on the population-scale shifts in activity resulting from these measures, especially outside of Europe and the US. This study uses satellite data to analyze how communities in 17 Middle Eastern countries adhered to COVID-19 measures. The findings reveal the inconsistent response to control measures both across and within countries, highlighting the challenges faced by conflict-afflicted states. The study demonstrates the utility of satellite measurements in assessing public response to physical distancing policies and the socio-cultural factors affecting their success, particularly in fragile and data-sparse regions.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Jan C. Kamp, Jan B. Hinrichs, Jan Fuge, Raphael Ewen, Jens Gottlieb
Summary: Patients after lung transplantation are at increased risk for life-threatening infections, including COVID-19. Studies on COVID-19 outcomes in this patient population are limited, but results show high mortality rates and hospitalizations. Survivors experience decline in exercise capacity and lung function, with stable anxiety, depression, and quality of life self-assessment. Charlson comorbidity index predicts mortality in these patients. Further research on long-term outcomes and impact on pre-existing CLAD are needed.
Article
Cardiac & Cardiovascular Systems
Katharina Schuetz, Jeanne Davids, Britta Petrik, Anna Zychlinsky Scharff, Julia Carlens, Albert Heim, Jawad Salman, Fabio Ius, Dmitry Bobylev, Gesine Hansen, Carsten Mueller, Nicolaus Schwerk
Summary: This study reported the clinical presentation and outcome of SARS-CoV-2 infection in 19 pediatric lung transplant recipients, indicating that children and adolescents with lung transplants are at low risk for severe COVID-19.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2023)
Article
Gastroenterology & Hepatology
Jordi Colmenero, Manuel Rodriguez-Peralvarez, Magdalena Salcedo, Ana Arias-Milla, Alejandro Munoz-Serrano, Javier Graus, Javier Nuno, Mikel Gastaca, Javier Bustamante-Schneider, Alba Cachero, Laura Llado, Aranzazu Caballero, Ainhoa Fernandez-Yunquera, Carmelo Loinaz, Inmaculada Fernandez, Constantino Fondevila, Miquel Navasa, Mercedes Inarrairaegui, Lluis Castells, Sonia Pascual, Pablo Ramirez, Carmen Vinaixa, Maria Luisa Gonzalez-Dieguez, Rocio Gonzalez-Grande, Loreto Hierro, Flor Nogueras, Alejandra Otero, Jose Maria Alamo, Gerardo Blanco-Fernandez, Emilio Fabrega, Fernando Garcia-Pajares, Jose Luis Montero, Santiago Tome, Gloria De la Rosa, Jose Antonio Pons
Summary: This study revealed that liver transplant patients have a higher risk of contracting COVID-19, but their mortality rate is lower than the general population. Baseline immunosuppression containing mycophenolate was identified as an independent predictor of severe COVID-19, especially at higher doses.
JOURNAL OF HEPATOLOGY
(2021)
Article
Virology
Gulay Yilmaz, Ozdemir Ebru, Berber Ibrahim, Cakir Ulkem
Summary: This study evaluated the general characteristics of kidney transplant recipients with COVID-19 infection, showing a significant increase in morbidity and mortality among these patients. Treatment involved withdrawing antimetabolites and increasing prednisolone, with a portion of patients requiring hospitalization.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Multidisciplinary Sciences
Asjad Naqvi
Summary: This tracker presents daily COVID-19 case data at the sub-national level for 26 European countries from January 2020 till present. It discusses the strengths and weaknesses of each country dataset and provides raw data and files for replication. The data highlights the spatial distribution of cases within and across countries for disaggregated analysis on the impacts of the pandemic and is updated monthly to expand coverage.
Article
Gastroenterology & Hepatology
Luca Saverio Belli, Christophe Duvoux, Paolo Angelo Cortesi, Rita Facchetti, Speranta Iacob, Giovanni Perricone, Sylvie Radenne, Sara Conti, Damiano Patrono, Gabriela Berlakovich, Angus Hann, Luisa Pasulo, Lluis Castells, Francois Faitot, Olivier Detry, Federica Invernizzi, Giulia Magini, Paolo De Simone, Ilias Kounis, Maria Cristina Morelli, Fernando Diaz Fontenla, Bo-Goran Ericzon, Carmelo Loinaz, Chris Johnston, Liliana Gheorghe, Mickael Lesurtel, Renato Romagnoli, Dagmar Kollmann, M. Thamara P. R. Perera, Stefano Fagiuoli, Darius Mirza, Audrey Coilly, Christian Toso, Krzysztof Zieniewicz, Laure Elkrief, Vincent Karam, Rene Adam, Caroline den Hoed, Marco Merli, Massimo Puoti, Luciano De Carlis, Gabriel C. Oniscu, Salvatore Piano, Paolo Angeli, Constantino Fondevila, Wojciech G. Polak
Summary: COVID-19 significantly impacts the mortality rate of liver transplant candidates, especially for those with high Lab-MELD scores and respiratory symptoms. Poor prognosis was observed in patients with decompensated cirrhosis, highlighting the need for strict preventive measures and urgent vaccination efficacy testing in this population. Prior symptomatic SARS-CoV-2 infection did not affect early post-transplant survival.
Editorial Material
Oncology
Shouki Bazarbashi, Ahmed Badran, Ahmed Mostafa Gad, Ali Aljubran, Ahmed Alzahrani, Aisha Alshibani, Reem Alrakaf, Tusneem Elhassan, Abdullah Alsuhaibani, Mahmoud A. Elshenawy
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Shouki Bazarbashi, Ahmed Badran, Ahmed Mostafa Gad, Ali Aljubran, Ahmed Alzahrani, Aisha Alshibani, Reem Alrakaf, Tusneem Elhassan, Abdullah Alsuhaibani, Mahmoud A. Elshenawy
Summary: The study found that prophylactic HIPEC and IORT after radical surgery for localized gastric or gastroesophageal cancer did not improve the risk of peritoneal recurrence.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Shouki Bazarbashi, Ahmed Alzahrani, Ali Aljubran, Mahmoud Elshenawy, Ahmed Mostafa Gad, Fatima Maraiki, Noura Alzannan, Tusneem Elhassan, Ahmed Badran
Summary: This study aimed to test the alternating use of sunitinib and bevacizumab for advanced clear cell renal cell carcinoma patients. The results showed that adding bevacizumab to sunitinib treatment can continuously block angiogenesis and effectively inhibit tumor growth with manageable toxicity.
Article
Medicine, General & Internal
Tusneem A. Elhassan, Mohd Shafry Mohd Rahim, Mohd Hashim Siti Zaiton, Tan Tian Swee, Taqwa Ahmed Alhaj, Abdulalem Ali, Mahmoud Aljurf
Summary: Recent advancements in AI have led to the development of a computer vision model for morphological classification of atypical white blood cells in acute myeloid leukemia. This model utilizes geometric transformation and deep convolutional autoencoder techniques to achieve accurate and efficient classification.
Article
Critical Care Medicine
Abdul Hakeem Al Hashim, Abdullah Al Reesi, Nabil M. Al Lawati, Jyoti Burad, Murtadha Al Khabori, Juhi Chandwani, Redha Al Lawati, Yahya Al Masroori, Abdul Aziz Al Balushi, Salim Al Masroori, Khalsa Al Siyabi, Fatema Al Lawati, Faroug Yousif Nimer Ahmed, Merah Al Busaidy, Aisha Al Huraizi, Mahmood Al Jufaili, Jalila Al Zaabi, Jerin Treesa Varghese, Ruqaya Al Harthi, Kingsly Prabhakaran Sebastian, Fahad Hamed Al Abri, Jamal Al Aghbari, Saif Al Mubaihsi, Adil Al Lawati, Mujahid Al Busaidi, Giuseppe Foti
Summary: This study compared the effectiveness of high-flow nasal cannula (HFNC), helmet, and face-mask noninvasive ventilation in COVID-19 patients with respiratory failure. The study found no significant difference in intubation rate and mortality among the three techniques.
CRITICAL CARE MEDICINE
(2023)
Review
Oncology
Riad El Fakih, Abdulwahab A. Albabtain, Saud Alhayli, Khawlah Farhan, Walid Rasheed, Alfadel Alshaibani, Naeem Chaudhri, Mahmoud Aljurf
Summary: This study retrospectively analyzed the safety and efficacy of using CPIs for cHL relapses post-allo-HCT in six patients. The results showed that CPIs maintained efficacy without any new safety concerns, even in patients who had failed to benefit from CPIs prior to allo-HCT.
SEMINARS IN ONCOLOGY
(2023)
Article
Endocrinology & Metabolism
Shouki Bazarbashi, Mohamed Aseafan, Tasnim Elgazzar, Maha Alkhayat, Abdulrahman Alghabban, Marwa I. I. Abdelgawad, Bader Alshamsan, Aisha Alshibany, Tusneem Elhassan, Ali Aljubran, Ahmed Alzahrani, Hindi Alhindi, Hussein Raef
Summary: This study aims to report the clinicopathological feature, treatment patterns, and survival outcomes of GEP-NET patients in the Middle East. The most common tumor location in this region was the pancreas, followed by the small bowel, stomach, rectum, colon, and appendix. Around 54.2% of the patients had metastatic disease at diagnosis. Patients who underwent surgical resection as primary management had significantly better survival outcomes.
BMC ENDOCRINE DISORDERS
(2023)
Review
Medicine, General & Internal
Amgad M. Elshoeibi, Khaled Ferih, Ahmed Adel Elsabagh, Basel Elsayed, Mohamed Elhadary, Mahmoud Marashi, Yasser Wali, Mona Al-Rasheed, Murtadha Al-Khabori, Hani Osman, Mohamed Yassin
Summary: Thrombocytopenia is a medical condition characterized by a very low blood platelet count, which can be caused by various factors including medication, sepsis, viral infections, and autoimmunity. Early detection and evaluation of thrombocytopenia are crucial for prompt and appropriate intervention. Artificial intelligence has shown great potential in the early diagnosis, prognosis assessment, and prediction of thrombocytopenia distribution by simultaneously considering multiple variables.
Review
Hematology
Riad El Fakih, Yazeed S. Bajuaifer, Amna Yousaf Shah, Reem Sulaiman, Rawan Almohamady, Ghada ELGohary, Haya S. Alothaimeen, Mahmoud Aljurf
Summary: Peripheral nervous system (PNS) manifestations of cancer, particularly in the context of classical Hodgkin lymphoma (cHL), are not well-studied. A systematic literature review was conducted, identifying 128 patients from 115 publications. Most patients had the nodular sclerosis (NS) subtype (66.4%). The most common clinical presentation of PNS was central nervous system (CNS) involvement (25.8%). The majority of patients were diagnosed with both cHL and PNS simultaneously (42.2%). The presence of PNS antibodies was reported in 35 patients (27.3%). Patients over 18 years old had a higher prevalence of PNS. The complete resolution rate of PNS was 54.7%. Relapse of lymphoma occurred in 13 patients, with PNS recurrence in 10 of them.
ANNALS OF HEMATOLOGY
(2023)
Review
Biophysics
Hanan Alkhaldi, Mohamed Kharfan-Dabaja, Riad El Fakih, Mahmoud Aljurf
Summary: The immune system is crucial in preventing infections and cancers, and impairment in immunity may contribute to the development of neoplasia. Immune evasion, including through checkpoint signaling pathways, plays a significant role in relapse after alloHCT. Checkpoint inhibitors have been approved for the treatment of relapsed cHL, PMBCL, and other solid tumors, but their use after alloHCT can lead to high rates of GVHD. The optimal timing, dosing, and patient selection for CPIs in post-alloHCT relapse remain uncertain.
BONE MARROW TRANSPLANTATION
(2023)
Letter
Biophysics
Riad El Fakih, Rayid Abdulqawi, Amer Bugnah, Tarek Ziad Arabi, Walid Rasheed, Loui Ezzat, Marwan Shaheen, Naeem Chaudhri, Fahad Almohareb, Eid A. Al-Mutairy, Mahmoud Aljurf
BONE MARROW TRANSPLANTATION
(2023)
Letter
Biophysics
Moussab Damlaj, Mohamed Tlayjeh, Ahmad Damlaj, Bader Alahmari, Husam AlSadi, Mazin Ahmed, Zied AlJubour, Ayman Alhejazi, Hend Salama, Ayman Ibrahim, Abdulrahman Al Raizah, Mohammed Bakkar, Abdulraouf Ghori, Abdullah S. Al Saleh, Ahmed Alaskar, Mohsen Alzahrani
BONE MARROW TRANSPLANTATION
(2023)
Meeting Abstract
Hematology
A. Haroon, R. El Fakih, H. Alzahrani
Meeting Abstract
Hematology
A. Haroon, R. El Fakih, H. Alzahrani
Meeting Abstract
Oncology
Reem Alasbali, Abdulrahman Nasiri, Saud Alhayli, Naeem Chaudhri, Alfadel Alshaibani, Abdulwahab Albabtain, Syed Ahmed Osman, Walid Rasheed, Riad El-Fakih, Mahmoud Aljurf, Ali Alahmari
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA
(2023)
