Fully integrated microfluidic devices for qualitative, quantitative and digital nucleic acids testing at point of care

Ultrafast Photonic PCR Based on Photothermal Nanomaterials

(2020) Minli You et al.   TRENDS IN BIOTECHNOLOGY

Sensitive detection of a bacterial pathogen using allosteric probe-initiated catalysis and CRISPR-Cas13a amplification reaction

(2020) Jinjin Shen et al.   Nature Communications

Integrated Microfluidic Sample-to-Answer System for Direct Nucleic Acid-Based Detection of Group B Streptococcus in Clinical Vaginal/Anal Swab Samples

(2020) Xin Ye et al.   ACS Sensors

Microfluidic-RT-LAMP chip for the point-of-care detection of emerging and re-emerging enteric coronaviruses in swine

(2020) Ling Zhou et al.   ANALYTICA CHIMICA ACTA

“Sample-to-Answer” Detection of Rare ctDNA Mutation from 2 mL Plasma with a Fully Integrated DNA Extraction and Digital Droplet PCR Microdevice for Liquid Biopsy

(2020) Zhi Geng et al.   ANALYTICAL CHEMISTRY

CRISPR–Cas12-based detection of SARS-CoV-2

(2020) James P. Broughton et al.   NATURE BIOTECHNOLOGY

Artificial intelligence–enabled rapid diagnosis of patients with COVID-19

(2020) Xueyan Mei et al.   NATURE MEDICINE

A fidget spinner for the point-of-care diagnosis of urinary tract infection

(2020) Issac Michael et al.   Nature Biomedical Engineering

A fully automated centrifugal microfluidic system for sample-to-answer viral nucleic acid testing

(2020) Fei Tian et al.   Science China-Chemistry

COVID-19: Disease, management, treatment, and social impact

(2020) Imran Ali et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Fabrication of a foldable all-in-one point-of-care molecular diagnostic microdevice for the facile identification of multiple pathogens

(2020) Kieu The Loan Trinh et al.   SENSORS AND ACTUATORS B-CHEMICAL

Ultrasensitive and visual detection of SARS-CoV-2 using all-in-one dual CRISPR-Cas12a assay

(2020) Xiong Ding et al.   Nature Communications

Advances in Reagents Storage and Release in Self-Contained Point-of-Care Devices

(2019) Jinqi Deng et al.   Advanced Materials Technologies

Evaluation and accurate diagnoses of pediatric diseases using artificial intelligence

(2019) Huiying Liang et al.   NATURE MEDICINE

Detection of unamplified target genes via CRISPR–Cas9 immobilized on a graphene field-effect transistor

(2019) Reza Hajian et al.   Nature Biomedical Engineering

Fully integrated and slidable paper-embedded plastic microdevice for point-of-care testing of multiple foodborne pathogens

(2019) Kieu The Loan Trinh et al.   BIOSENSORS & BIOELECTRONICS

Smartphone-Based Droplet Digital LAMP Device with Rapid Nucleic Acid Isolation for Highly Sensitive Point-of-Care Detection

(2019) Fei Hu et al.   ANALYTICAL CHEMISTRY

Semiquantitative Nucleic Acid Test with Simultaneous Isotachophoretic Extraction and Amplification

(2018) Andrew T. Bender et al.   ANALYTICAL CHEMISTRY

Nucleic acid-based electrochemical nanobiosensors

(2018) Alireza Abi et al.   BIOSENSORS & BIOELECTRONICS

Nucleic acid aptamer-based methods for diagnosis of infections

(2018) Ki Soo Park   BIOSENSORS & BIOELECTRONICS

Fully 3D printed integrated reactor array for point-of-care molecular diagnostics

(2018) Karteek Kadimisetty et al.   BIOSENSORS & BIOELECTRONICS

A microdevice for rapid, monoplex and colorimetric detection of foodborne pathogens using a centrifugal microfluidic platform

(2018) Abkar Sayad et al.   BIOSENSORS & BIOELECTRONICS

A novel exonuclease-assisted isothermal nucleic acid amplification with ultrahigh specificity mediated by full-length Bst DNA polymerase

(2018) Xin Ye et al.   CHEMICAL COMMUNICATIONS

An exploration of nucleic acid liquid biopsy using a glucose meter

(2018) Yu Gu et al.   Chemical Science

Rapid oral bacteria detection based on real-time PCR for the forensic identification of saliva

(2018) Ju Yeon Jung et al.   Scientific Reports

Ultrasensitive detection of miRNA with an antimonene-based surface plasmon resonance sensor

(2018) Tianyu Xue et al.   Nature Communications

A Sample-to-Targeted Gene Analysis Biochip for Nanofluidic Manipulation of Solid-Phase Circulating Tumor Nucleic Acid Amplification in Liquid Biopsies

(2018) Kevin M. Koo et al.   ACS Sensors

Artificial intelligence in healthcare

(2018) Kun-Hsing Yu et al.   Nature Biomedical Engineering

Fully integrated nucleic acid pretreatment, amplification, and detection on a paper chip for identifying EGFR mutations in lung cancer cells

(2018) Peng Chen et al.   SENSORS AND ACTUATORS B-CHEMICAL

A fully disposable and integrated paper-based device for nucleic acid extraction, amplification and detection

(2017) Ruihua Tang et al.   LAB ON A CHIP

Point-of-care-testing of nucleic acids by microfluidics

(2017) Lu Zhang et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Rapid and simple detection of foot-and-mouth disease virus: Evaluation of a cartridge-based molecular detection system for use in basic laboratories

(2017) K. V. Goller et al.   Transboundary and Emerging Diseases

A Paper-Based Device for Performing Loop-Mediated Isothermal Amplification with Real-Time Simultaneous Detection of Multiple DNA Targets

(2017) Youngung Seok et al.   Theranostics

A rapid molecular diagnosis of cutaneous leishmaniasis by colorimetric malachite green-loop-mediated isothermal amplification (LAMP) combined with an FTA card as a direct sampling tool

(2016) Chukwunonso O. Nzelu et al.   ACTA TROPICA

An integrated lateral flow assay for effective DNA amplification and detection at the point of care

(2016) Jane Ru Choi et al.   ANALYST

High-throughput sample-to-answer detection of DNA/RNA in crude samples within functionalized micro-pipette tips

(2016) Wenjing Lu et al.   BIOSENSORS & BIOELECTRONICS

Fully automated and colorimetric foodborne pathogen detection on an integrated centrifugal microfluidic device

(2016) Seung Jun Oh et al.   LAB ON A CHIP

Polymerase chain reaction in microfluidic devices

(2016) Christian D. Ahrberg et al.   LAB ON A CHIP

An integrated paper-based sample-to-answer biosensor for nucleic acid testing at the point of care

(2016) Jane Ru Choi et al.   LAB ON A CHIP

A rapid, instrument-free, sample-to-result nucleic acid amplification test

(2016) Lisa K. Lafleur et al.   LAB ON A CHIP

Smart cup: A minimally-instrumented, smartphone-based point-of-care molecular diagnostic device

(2016) Shih-Chuan Liao et al.   SENSORS AND ACTUATORS B-CHEMICAL

Integrated Electrochemical Microsystems for Genetic Detection of Pathogens at the Point of Care

(2015) Kuangwen Hsieh et al.   ACCOUNTS OF CHEMICAL RESEARCH

“Paper Machine” for Molecular Diagnostics

(2015) John T. Connelly et al.   ANALYTICAL CHEMISTRY

Rapid detection and typing of live bacteria from human joint fluid samples by utilizing an integrated microfluidic system

(2015) Wen-Hsin Chang et al.   BIOSENSORS & BIOELECTRONICS

Isothermal Amplification of Nucleic Acids

(2015) Yongxi Zhao et al.   CHEMICAL REVIEWS

Developmental validation of a fully integrated sample-to-profile rapid human identification system for processing single-source reference buccal samples

(2015) Stevan Jovanovich et al.   Forensic Science International-Genetics

A lab-on-a-chip system with integrated sample preparation and loop-mediated isothermal amplification for rapid and quantitative detection of Salmonella spp. in food samples

(2015) Yi Sun et al.   LAB ON A CHIP

Integrated, DC voltage-driven nucleic acid diagnostic platform for real sample analysis: Detection of oral cancer

(2015) Zdenek Slouka et al.   TALANTA