The interaction between brain and liver regulates lipid metabolism in the TBI pathology

Beyond the brain: peripheral interactions following traumatic brain injury

(2020) Jessica May Sharkey et al.   JOURNAL OF NEUROTRAUMA

Nicotinamide attenuates the decrease in dendritic spine density in hippocampal primary neurons from 5xFAD mice, an Alzheimer’s disease animal model

(2020) Hyunju Kim et al.   Molecular Brain

Lysophosphatidylcholine Induces NLRP3 Inflammasome-Mediated Foam Cell Formation and Pyroptosis in Human Monocytes and Endothelial Cells

(2020) Rafael Corrêa et al.   Frontiers in Immunology

Mitochondrial damage & lipid signaling in traumatic brain injury

(2020) Andrew M. Lamade et al.   EXPERIMENTAL NEUROLOGY

Longitudinal characterization of blood-brain barrier permeability after experimental traumatic brain injury by in vivo 2-photon microscopy

(2020) Yue Hu et al.   JOURNAL OF NEUROTRAUMA

Brain Trauma Disrupts Hepatic Lipid Metabolism: Blame it on Fructose?

(2019) Shraddha D. Rege et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Serum Amyloid A Protein as a Potential Biomarker for Severity and Acute Outcome in Traumatic Brain Injury

(2019) Evan Wicker et al.   Biomed Research International

PLA2G4A/cPLA2-mediated lysosomal membrane damage leads to inhibition of autophagy and neurodegeneration after brain trauma

(2019) Chinmoy Sarkar et al.   Autophagy

Elevated Serum Levels of Inflammation-Related Cytokines in Mild Traumatic Brain Injury Are Associated With Cognitive Performance

(2019) Yingxiang Sun et al.   Frontiers in Neurology

Inhibition of GABA A receptor improved special memory impairment in the local model of demyelination in rat hippocampus

(2018) Alireza Mousavi Majd et al.   BEHAVIOURAL BRAIN RESEARCH

Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model

(2018) Chad A Tagge et al.   BRAIN

OXIDIZED PHOSPHOLIPID SIGNALING IN TRAUMATIC BRAIN INJURY

(2018) Tamil S. Anthonymuthu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Alterations in the Plasma Levels of Specific Choline Phospholipids in Alzheimer’s Disease Mimic Accelerated Aging

(2018) Fabian Dorninger et al.   JOURNAL OF ALZHEIMERS DISEASE

Lysophosphatidylcholine and its phosphorothioate analogues potentiate insulin secretion via GPR40 (FFAR1), GPR55 and GPR119 receptors in a different manner

(2018) Anna Drzazga et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Differentiation in Response to Lysolecithin-Induced Demyelination

(2018) Changqing Lu et al.   Scientific Reports

Cognitive Changes and Brain Volume Reduction in Patients with Nonalcoholic Fatty Liver Disease

(2018) Branka Filipović et al.   Canadian Journal of Gastroenterology and Hepatology

Adipocyte-derived Lysophosphatidylcholine Activates Adipocyte and Adipose Tissue Macrophage Nod-Like Receptor Protein 3 Inflammasomes Mediating Homocysteine-Induced Insulin Resistance

(2018) Song-Yang Zhang et al.   EBioMedicine

Identification of Lysophosphatidylcholines and Sphingolipids as Potential Biomarkers for Acute Aortic Dissection via Serum Metabolomics

(2018) Xiushi Zhou et al.   EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY

Caspase-independent hepatocyte death: A result of the decrease of lysophosphatidylcholine acyltransferase 3 in non-alcoholic steatohepatitis

(2018) Keisuke Kakisaka et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Neuroprotective effect of l-serine against white matter demyelination by harnessing and modulating inflammation in mice

(2018) Guohua Wang et al.   NEUROPHARMACOLOGY

Triglycerides cross the blood–brain barrier and induce central leptin and insulin receptor resistance

(2017) W A Banks et al.   INTERNATIONAL JOURNAL OF OBESITY

NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes

(2017) Leslie Freeman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lipid Processing in the Brain: A Key Regulator of Systemic Metabolism

(2017) Kimberley D. Bruce et al.   Frontiers in Endocrinology

Hepatic alterations are accompanied by changes to bile acid transporter-expressing neurons in the hypothalamus after traumatic brain injury

(2017) Damir Nizamutdinov et al.   Scientific Reports

Blood–Brain Barrier Dysfunction as a Hallmark Pathology in Chronic Traumatic Encephalopathy

(2016) Colin P. Doherty et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The Presence of White Matter Lesions Is Associated With the Fibrosis Severity of Nonalcoholic Fatty Liver Disease

(2016) Salvatore Petta et al.   MEDICINE

Nonalcoholic fatty liver disease is associated with cognitive function in adults

(2016) Sang Won Seo et al.   NEUROLOGY

Hepatic Expression of Serum Amyloid A1 Is Induced by Traumatic Brain Injury and Modulated by Telmisartan

(2015) Sonia Villapol et al.   AMERICAN JOURNAL OF PATHOLOGY

Lipids in the nervous system: From biochemistry and molecular biology to patho-physiology

(2015) Gaia Cermenati et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration

(2015) Lucy Liu et al.   CELL

Dietary fructose aggravates the pathobiology of traumatic brain injury by influencing energy homeostasis and plasticity

(2015) Rahul Agrawal et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cerebral white matter lesions in patients with cirrhosis - causative for hepatic encephalopathy or bystanders?

(2015) Henning Pflugrad et al.   LIVER INTERNATIONAL

Delayed Increases in Microvascular Pathology after Experimental Traumatic Brain Injury Are Associated with Prolonged Inflammation, Blood–Brain Barrier Disruption, and Progressive White Matter Damage

(2014) Olena Y. Glushakova et al.   JOURNAL OF NEUROTRAUMA

Activated microglia in ischemic stroke penumbra upregulate MCP-1 and CCR2 expression in response to lysophosphatidylcholine derived from adjacent neurons and astrocytes

(2014) Yuri Inose et al.   NEUROPATHOLOGY

High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase

(2013) Takuji Ishimoto et al.   HEPATOLOGY

Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome

(2013) Miguel A. Lanaspa et al.   Nature Communications

The Role of Markers of Inflammation in Traumatic Brain Injury

(2013) Thomas Woodcock et al.   Frontiers in Neurology

Prevention of 1-palmitoyl lysophosphatidylcholine-induced inflammation by polyunsaturated acyl lysophosphatidylcholine

(2012) Nguyen Dang Hung et al.   INFLAMMATION RESEARCH

Lysophosphatidylcholine Acyltransferase 3 Knockdown-mediated Liver Lysophosphatidylcholine Accumulation Promotes Very Low Density Lipoprotein Production by Enhancing Microsomal Triglyceride Transfer Protein Expression

(2012) Zhiqiang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

‘Metabolic syndrome’ in the brain: deficiency in omega-3 fatty acid exacerbates dysfunctions in insulin receptor signalling and cognition

(2012) Rahul Agrawal et al.   JOURNAL OF PHYSIOLOGY-LONDON

Lipoprotein-Derived Lysophosphatidic Acid Promotes Atherosclerosis by Releasing CXCL1 from the Endothelium

(2011) Zhe Zhou et al.   Cell Metabolism

From brain to food: Analysis of phosphatidylcholins, lyso-phosphatidylcholins and phosphatidylcholin–plasmalogens derivates in Alzheimer's disease human post mortem brains and mice model via mass spectrometry

(2011) Marcus O.W. Grimm et al.   JOURNAL OF CHROMATOGRAPHY A

Group 1B phospholipase A2deficiency protects against diet-induced hyperlipidemia in mice

(2011) Norris I. Hollie et al.   JOURNAL OF LIPID RESEARCH

Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease

(2010) Manal F. Abdelmalek et al.   HEPATOLOGY

Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans

(2009) Kimber L. Stanhope et al.   JOURNAL OF CLINICAL INVESTIGATION

Full Accounting of Diabetes and Pre-Diabetes in the U.S. Population in 1988-1994 and 2005-2006

(2008) C. C. Cowie et al.   DIABETES CARE

Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet

(2008) Mary E. Rinella et al.   JOURNAL OF LIPID RESEARCH