Can non-cholesterol sterols indicate the presence of specific dysregulation of cholesterol metabolism in patients with colorectal cancer?

Revealing the Role of High-Density Lipoprotein in Colorectal Cancer

(2021) Aleksandra Zeljkovic et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer

(2020) Linara Gabitova-Cornell et al.   CANCER CELL

Low high-density lipoprotein and increased risk of several cancers: 2 population-based cohort studies including 116,728 individuals

(2020) Kasper Mønsted Pedersen et al.   Journal of Hematology & Oncology

The emerging concept of “individualized cholesterol-lowering therapy”: A change in paradigm

(2019) Dieter Lütjohann et al.   PHARMACOLOGY & THERAPEUTICS

Role of cholesterol homeostasis and its efflux pathways in cancer progression

(2019) Bhoomika Sharma et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Clinical relevance of cholesterol homeostasis genes in colorectal cancer

(2019) Bhoomika Sharma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Even Cancer Cells Watch Their Cholesterol!

(2019) Romain Riscal et al.   MOLECULAR CELL

The tumor-suppressor cholesterol metabolite, dendrogenin A, is a new class of LXR modulator activating lethal autophagy in cancers

(2018) Marc Poirot et al.   BIOCHEMICAL PHARMACOLOGY

Preanalytical and analytical challenges in gas chromatographic determination of cholesterol synthesis and absorption markers

(2018) Tamara Gojkovic et al.   CLINICA CHIMICA ACTA

Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages

(2018) Evan D. Muse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Effects of Cholesterol-Derived Oncometabolites on Nuclear Receptor Function in Cancer

(2018) Sandrine Silvente-Poirot et al.   CANCER RESEARCH

ABCA1 overexpression worsens colorectal cancer prognosis by facilitating tumour growth and caveolin-1-dependent invasiveness, and these effects can be ameliorated using the BET inhibitor apabetalone

(2018) Cristina Aguirre-Portolés et al.   Molecular Oncology

Aberrant lipid metabolism in cancer cells - the role of oncolipid-activated signaling

(2017) Upasana Ray et al.   FEBS Journal

Functional role of extracellular vesicles and lipoproteins in the tumour microenvironment

(2017) Julien A. Menard et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Role of Cholesterol in Cancer

(2016) Omer F. Kuzu et al.   CANCER RESEARCH

Targeting the SR-B1 Receptor as a Gateway for Cancer Therapy and Imaging

(2016) Linda K. Mooberry et al.   Frontiers in Pharmacology

Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways

(2015) Matthew A Mitsche et al.   eLife

High-density lipoprotein metabolism, composition, function, and deficiency

(2014) Ernst J. Schaefer et al.   CURRENT OPINION IN LIPIDOLOGY

Oxidation of 7-dehydrocholesterol and desmosterol by human cytochrome P450 46A1

(2014) Sandeep Goyal et al.   JOURNAL OF LIPID RESEARCH

Molecular Pathways: Sterols and Receptor Signaling in Cancer

(2013) L. Gabitova et al.   CLINICAL CANCER RESEARCH

Cholesterol precursors

(2013) Andrew J. Brown et al.   CURRENT OPINION IN LIPIDOLOGY

The role of cholesterol metabolism and cholesterol transport in carcinogenesis: a review of scientific findings, relevant to future cancer therapeutics

(2013) Pedro M. R. Cruz et al.   Frontiers in Pharmacology

Regulated Accumulation of Desmosterol Integrates Macrophage Lipid Metabolism and Inflammatory Responses

(2012) Nathanael J. Spann et al.   CELL

Cholesterol metabolism and cancer: the good, the bad and the ugly

(2012) Sandrine Silvente-Poirot et al.   CURRENT OPINION IN PHARMACOLOGY

Regulation of cholesterol homeostasis

(2012) Mariëtte Y.M. van der Wulp et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Targeting C4-Demethylating Genes in the Cholesterol Pathway Sensitizes Cancer Cells to EGF Receptor Inhibitors via Increased EGF Receptor Degradation

(2012) Anna Sukhanova et al.   Cancer Discovery

Cell cholesterol homeostasis: Mediation by active cholesterol

(2010) Theodore L. Steck et al.   TRENDS IN CELL BIOLOGY

Tamoxifen and AEBS ligands induced apoptosis and autophagy in breast cancer cells through the stimulation of sterol accumulation

(2009) Philippe de Medina et al.   Autophagy

Desmosterol can replace cholesterol in sustaining cell proliferation and regulating the SREBP pathway in a sterol-Δ24-reductase-deficient cell line

(2009) Sara Rodríguez-Acebes et al.   BIOCHEMICAL JOURNAL

Inhibition of 11β–hydroxysteroid dehydrogenase type II selectively blocks the tumor COX-2 pathway and suppresses colon carcinogenesis in mice and humans

(2009) Ming-Zhi Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Serum lipoproteins and cancer

(2008) S. Muntoni et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES