Genome-Wide Association Study and Identification of a Protective Missense Variant on Lipoprotein(a) Concentration

Role of Rare and Low-Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels

(2020) Zhe Wang et al.   Circulation-Genomic and Precision Medicine

Exome sequencing and characterization of 49,960 individuals in the UK Biobank

(2020) Cristopher V. Van Hout et al.   NATURE

Lipoprotein(a): The renaissance of an enigmatic lipoprotein

(2019) Robin P F Dullaart   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

LPAVariants are Associated with Residual Cardiovascular Risk in Patients Receiving Statins

(2018) Wei-Qi Wei et al.   CIRCULATION

PCSK9 inhibition and Lp(a) reduction: another piece of the puzzle?

(2018) Angela Pirillo et al.   EUROPEAN HEART JOURNAL

Evaluating the potential role of pleiotropy in Mendelian randomization studies

(2018) Gibran Hemani et al.   HUMAN MOLECULAR GENETICS

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

(2018) Marie Verbanck et al.   NATURE GENETICS

From genome-wide associations to candidate causal variants by statistical fine-mapping

(2018) Daniel J. Schaid et al.   NATURE REVIEWS GENETICS

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

(2018) Seyedeh M. Zekavat et al.   Nature Communications

Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians

(2018) Neil M Davies et al.   BMJ-British Medical Journal

Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians

(2018) Neil M Davies et al.   BMJ-British Medical Journal

Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies

(2018) Stephen Burgess et al.   JAMA Cardiology

An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings

(2018) Eleanor Sanderson et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program

(2018) Derek Klarin et al.   NATURE GENETICS

Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption

(2017) Fernando Pires Hartwig et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms

(2017) Salome Mack et al.   JOURNAL OF LIPID RESEARCH

A Test in Context: Lipoprotein(a)

(2017) Sotirios Tsimikas   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A framework for the investigation of pleiotropy in two-sample summary data Mendelian randomization

(2017) Jack Bowden et al.   STATISTICS IN MEDICINE

Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease: a mendelian randomisation analysis

(2017) Danish Saleheen et al.   Lancet Diabetes & Endocrinology

FINEMAP: efficient variable selection using summary data from genome-wide association studies

(2016) Christian Benner et al.   BIOINFORMATICS

Structure, function, and genetics of lipoprotein (a)

(2016) Konrad Schmidt et al.   JOURNAL OF LIPID RESEARCH

Evidence for several independent genetic variants affecting lipoprotein (a) cholesterol levels

(2015) W. Lu et al.   HUMAN MOLECULAR GENETICS

Genome- and exome-wide association study of serum lipoprotein (a) in the Jackson Heart Study

(2015) Jin Li et al.   JOURNAL OF HUMAN GENETICS

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

Efficient Bayesian mixed-model analysis increases association power in large cohorts

(2015) Po-Ru Loh et al.   NATURE GENETICS

Detecting pleiotropy in Mendelian randomisation studies with summary data and a continuous outcome

(2015) Fabiola Del Greco M et al.   STATISTICS IN MEDICINE

Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

(2015) Elisabeth M. van Leeuwen et al.   Nature Communications

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Phospholipid methylation in mammals: from biochemistry to physiological function

(2013) Dennis E. Vance   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Lipoprotein(a): resurrected by genetics

(2013) F. Kronenberg et al.   JOURNAL OF INTERNAL MEDICINE

Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts

(2011) Delilah Zabaneh et al.   ATHEROSCLEROSIS

Using multiple genetic variants as instrumental variables for modifiable risk factors

(2011) Tom M Palmer et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

Lipoprotein(a) Concentration and the Risk of Coronary Heart Disease, Stroke, and Nonvascular Mortality

(2009)   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genetic Variants Associated with Lp(a) Lipoprotein Level and Coronary Disease

(2009) Robert Clarke et al.   NEW ENGLAND JOURNAL OF MEDICINE