Loss of TIMP4 (Tissue Inhibitor of Metalloproteinase 4) Promotes Atherosclerotic Plaque Deposition in the Abdominal Aorta Despite Suppressed Plasma Cholesterol Levels

Immunity and Inflammation in Atherosclerosis

(2019) Dennis Wolf et al.   CIRCULATION RESEARCH

Smooth Muscle Cells Contribute the Majority of Foam Cells in ApoE (Apolipoprotein E)-Deficient Mouse Atherosclerosis

(2019) Ying Wang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vascular smooth muscle cells in atherosclerosis

(2019) Gemma L. Basatemur et al.   Nature Reviews Cardiology

Atherosclerosis

(2019) Peter Libby et al.   Nature Reviews Disease Primers

Extracellular matrix, regional heterogeneity of the aorta, and aortic aneurysm

(2019) Sayantan Jana et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Macrophages Shed Excess Cholesterol in Unique Extracellular Structures Containing Cholesterol MicrodomainsHighlights

(2018) Xueting Jin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cell-Specific Functions of ADAM17 Regulate the Progression of Thoracic Aortic AneurysmNovelty and Significance

(2018) Mengcheng Shen et al.   CIRCULATION RESEARCH

Differential hypertensive protease expression in the thoracic versus abdominal aorta

(2017) Jean Marie Ruddy et al.   JOURNAL OF VASCULAR SURGERY

Absence of Tissue Inhibitor of Metalloproteinase-4 (TIMP4) ameliorates high fat diet-induced obesity in mice due to defective lipid absorption

(2017) Siva S. V. P. Sakamuri et al.   Scientific Reports

Triglyceride-Rich Lipoproteins and Atherosclerotic Cardiovascular Disease

(2016) Børge G. Nordestgaard   CIRCULATION RESEARCH

Atherosclerosis

(2016) Peter Libby et al.   CIRCULATION RESEARCH

Epidemiology of Atherosclerosis and the Potential to Reduce the Global Burden of Atherothrombotic Disease

(2016) William Herrington et al.   CIRCULATION RESEARCH

Multidimensional Contribution of Matrix Metalloproteinases to Atherosclerotic Plaque Vulnerability: Multiple Mechanisms of Inhibition to Promote Stability

(2016) Jean Marie Ruddy et al.   JOURNAL OF VASCULAR RESEARCH

Divergent Roles of Matrix Metalloproteinase 2 in Pathogenesis of Thoracic Aortic AneurysmSignificance

(2015) Mengcheng Shen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Differential effects of tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 on atherosclerosis and monocyte/macrophage invasion

(2015) Karina Di Gregoli et al.   CARDIOVASCULAR RESEARCH

Protective Role for Tissue Inhibitor of Metalloproteinase-4, a Novel Peroxisome Proliferator–Activated Receptor-γ Target Gene, in Smooth Muscle in Deoxycorticosterone Acetate–Salt HypertensionNovelty and Significance

(2015) Pimonrat Ketsawatsomkron et al.   HYPERTENSION

KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis

(2015) Laura S Shankman et al.   NATURE MEDICINE

Loss of TIMP3 exacerbates atherosclerosis in ApoE null mice

(2014) Robert Stöhr et al.   ATHEROSCLEROSIS

MicroRNA-27a/b regulates cellular cholesterol efflux, influx and esterification/hydrolysis in THP-1 macrophages

(2014) Min Zhang et al.   ATHEROSCLEROSIS

Contribution of Intimal Smooth Muscle Cells to Cholesterol Accumulation and Macrophage-Like Cells in Human Atherosclerosis

(2014) Sima Allahverdian et al.   CIRCULATION

Transdifferentiation of Vascular Smooth Muscle Cells to Macrophage-Like Cells During Atherogenesis

(2014) Susanne Feil et al.   CIRCULATION RESEARCH

Macrophage Functions in Atherosclerosis

(2014) Iris Zeller et al.   CIRCULATION RESEARCH

Angiotensin-Converting Enzyme 2 Is a Critical Determinant of Angiotensin II–Induced Loss of Vascular Smooth Muscle Cells and Adverse Vascular Remodeling

(2014) Vaibhav B. Patel et al.   HYPERTENSION

Relationship of MMP-14 and TIMP-3 Expression with Macrophage Activation and Human Atherosclerotic Plaque Vulnerability

(2014) Jason L. Johnson et al.   MEDIATORS OF INFLAMMATION

Pathophysiology of Thoracic Aortic Aneurysm (TAA): Is It Not One Uniform Aorta? Role of Embryologic Origin

(2013) Jean Marie Ruddy et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Loss ofTimp3Gene Leads to Abdominal Aortic Aneurysm Formation in Response to Angiotensin II

(2012) Ratnadeep Basu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpression of Tissue Inhibitor of Metalloproteinase 3 in Macrophages Reduces Atherosclerosis in Low-Density Lipoprotein Receptor Knockout Mice

(2011) Viviana Casagrande et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Biological role of matrix metalloproteinases: a critical balance

(2010) S. Loffek et al.   EUROPEAN RESPIRATORY JOURNAL

Polymorphisms of MMP-3 and TIMP-4 genes affect angiographic coronary plaque progression in non-diabetic and type 2 diabetic patients

(2009) Qiu Jing Chen et al.   CLINICA CHIMICA ACTA

Regional heterogeneity within the aorta: Relevance to aneurysm disease

(2008) Jean Marie Ruddy et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY