Article
Oncology
Viviane A. Lin, Robin Lohse, Michael T. Madsen, Tina Fransgaard, Feza H. Remzi, Ismail Goegenur
Summary: This study found no significant differences in long-term outcomes between patients with ulcerative colitis-associated colorectal cancer and those with sporadic colorectal cancer. However, the results are limited by potential residual confounding and heterogeneity in confounding adjustment during the meta-analysis.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Article
Oncology
Keyi Yang, Daniela Doege, Melissa S. Y. Thong, Lena Koch-Gallenkamp, Linda Weisser, Heike Bertram, Andrea Eberle, Bernd Holleczek, Alice Nennecke, Annika Waldmann, Sylke Ruth Zeissig, Ron Pritzkuleit, Lina Jansen, Hermann Brenner, Volker Arndt
Summary: The prevalence of diabetes mellitus (DM) in cancer survivors is not higher than in cancer-free controls, however, cancer survivors with DM have a potentially increased risk of mortality.
Review
Oncology
Janne de Winter, Nicole P. M. Ezendam, Martijn J. L. Bours, Renate M. Winkels, Matty P. Weijenberg, Ellen Kampman, Pauline A. J. Vissers, Floortje Mols, Sandra Beijer
Summary: This study found that poor sleep quality and short sleep duration were not associated with higher BMI, WC, or diet quality among colorectal cancer survivors, which differs from findings in the general population.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Oncology
Janette L. Vardy, Gregory R. Pond, Lucette A. Cysique, Thomas M. Gates, Jim Lagopoulos, Corrinne Renton, Louise M. Waite, Ian F. Tannock, Haryana M. Dhillon
Summary: There was no difference in cognitive capacity and function between CRC survivors and controls 6-12 years after diagnosis. Differences in neuroimaging require confirmation in a larger sample.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Oncology
Giulia Turri, Gulser Caliskan, Cristian Conti, Luigi Martinelli, Ernesto De Giulio, Andrea Ruzzenente, Alfredo Guglielmi, Giuseppe Verlato, Corrado Pedrazzani
Summary: As the world population ages, more and more elderly patients will require cancer surgery. This study aimed to evaluate the impact of age and comorbidities on postoperative outcomes and long-term survival, and identify potential age-related survival differences.
FRONTIERS IN ONCOLOGY
(2022)
Article
Immunology
Hayoung Choi, Kyungdo Han, Jin-Hyung Jung, Sang Hyun Park, Sang Hyuk Kim, Hyung Koo Kang, Jang Won Sohn, Dong Wook Shin, Hyun Lee
Summary: The long-term mortality risk in this study was significantly higher in tuberculosis survivors than those in the matched controls, even after adjusting for potential confounders, including behavior habits, income level, body mass index, and comorbidities.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Immunology
Qun Zhang, Yuan Dai, Hongda Liu, Wenkui Sun, Yuming Huang, Zheng Gong, Shanlin Dai, Hui Kong, Weiping Xie
Summary: This retrospective cohort study aimed to determine the time-dependent death hazards of various causes and conditional survival of lung cancer. The study found that non-lung cancer related death risk becomes more predominant over time, and established a personalized web-based calculator to determine the critical time point for long-term survivors. The study also confirmed the survival benefit of advanced lung cancer patients in the era of immunotherapy.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Oncology
Xuan Quy Luu, Kyeongmin Lee, Jae Kwan Jun, Mina Suh, Kyu-Won Jung, Kui Son Choi
Summary: This study investigated the long-term survival effects of colorectal cancer screening based on screening history and interval time since screening. The results showed that colorectal cancer screening was positively associated with favorable prognosis, especially among individuals screened within 1 year before diagnosis.
INTERNATIONAL JOURNAL OF CANCER
(2022)
Article
Oncology
A. K. Warps, R. A. E. M. Tollenaar, P. J. Tanis, J. W. T. Dekker
Summary: Complications after colorectal cancer surgery can have a significant impact on long-term survival. Non-surgical complications have a greater effect on survival than surgical complications. The impact of surgical complications on survival is still measurable in rectal cancer patients after surviving the first year, but not in colon cancer patients.
Article
Oncology
Jason L. Oke, Sarah Jo Brown, Chris Senger, H. Gilbert Welch
Summary: The NHS Long Term Plan for cancer aims to increase early-stage diagnoses and long-term survival rates. However, the current measurement methods are flawed and do not reflect outcomes that matter to patients. Switching to unbiased population-based measures is essential for reducing late-stage incidence and mortality in cancer care.
BRITISH JOURNAL OF CANCER
(2023)
Article
Oncology
Natassia Robinson, John Casement, Marc J. Gunter, Inge Huybrechts, Antonio Agudo, Miguel Rodriguez Barranco, Fabian Eichelmann, Theron Johnson, Rudolf Kaaks, Valeria Pala, Salvatore Panico, Torkjel M. Sandanger, Matthias B. Schultze, Ruth C. Travis, Rosario Tumino, Paolo Vineis, Elisabete Weiderpass, Roderick Skinner, Linda Sharp, Jill A. McKay, Gordon Strathdee
Summary: This study identifies widespread DNA methylation changes in childhood cancer patients post-treatment, which may have long-term retention. Adult survivors also exhibit epigenetic age acceleration, independent of DMR methylation. Altered methylation at the DUSP6 DMR is significantly associated with early mortality. These findings highlight the importance of these methylation changes as potential biomarkers for assessing treatment toxicity and predicting long-term health outcomes in childhood cancer survivors.
BRITISH JOURNAL OF CANCER
(2022)
Article
Surgery
Shao-Hua Xie, Giola Santoni, Kalle Malberg, Pernilla Lagergren, Jesper Lagergren
Summary: The study developed prediction models for estimating long-term survival in patients who underwent esophageal cancer surgery, including 1-, 3-, and 5-year all-cause mortality, and 3- and 5-year disease-specific mortality. These models showed good performance and may serve as useful tools for guiding patient life planning and postoperative treatment.
Article
Oncology
Debbie Smit, Floortje Mols, Cynthia S. Bonhof, Martijn J. L. Bours, Gerard Vreugdenhil, Sandra Beijer
Summary: The study found that 64% of CRC survivors experienced CIPN several years after chemotherapy, with only SAT being associated with total, motor, and sensory CIPN. This suggests that determining chemotherapy dose based on body composition may not be the preferred method in preventing CIPN. Further research is needed to explore the associations of body composition with CIPN, a common side effect of chemotherapy.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Cardiac & Cardiovascular Systems
Zhipeng Wang, Zeyu Fan, Lei Yang, Lifang Liu, Chao Sheng, Fengju Song, Yubei Huang, Kexin Chen
Summary: This study found that cardiovascular death gradually outweighs cancer death as survival time increases for most cancer patients. Older age and local metastasis are independent risk factors for cardiovascular death, while being women, undergoing surgery, and receiving chemotherapy are associated with a decreased risk of cardiovascular death.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Oncology
Gaya Spolverato, Giulia Capelli, Jessica Battagello, Andrea Barina, Susi Nordio, Elena Finotti, Isabella Mondi, Corrado Da Lio, Emilio Morpurgo, Jose Adolfo Navarro, Fabio Ceccato, Alessandro Perin, Corrado Pedrazzani, Giulia Turri, Giacomo Zanus, Michela Campi, Marco Massani, Adriana Di Giacomo, Daniela Prando, Ferdinando Agresta, Salvatore Pucciarelli, Manuel Zorzi, Massimo Rugge
Summary: A study found that background screening for colorectal cancer significantly reduces mortality, with screen-detected tumors associating with better prognosis. Among patients undergoing surgery, those with screen-detected tumors are typically diagnosed at an earlier stage and have better long-term outcomes.
FRONTIERS IN ONCOLOGY
(2021)