A novel tau‐based rhesus monkey model of Alzheimer's pathogenesis

Cell-to-Cell Transmission of Tau and α-Synuclein

(2020) Norihito Uemura et al.   TRENDS IN MOLECULAR MEDICINE

Combining P301L and S320F tau variants produces a novel accelerated model of tauopathy

(2019) Emily J Koller et al.   HUMAN MOLECULAR GENETICS

Tau isoform expression and phosphorylation in marmoset brains

(2019) Govinda Sharma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oligomeric Aβ in the monkey brain impacts synaptic integrity and induces accelerated cortical aging

(2019) Danielle Beckman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The aged rhesus macaque manifests Braak stage III/IV Alzheimer's-like pathology

(2018) Constantinos D. Paspalas et al.   Alzheimers & Dementia

Microglia and Astrocytes in Alzheimer's Disease: Implications for Therapy

(2018) Marc Fakhoury   Current Neuropharmacology

Tau filaments in neurodegenerative diseases

(2018) Michel Goedert   FEBS LETTERS

Future directions in animal models of Alzheimer’s disease

(2018) Danielle Beckman et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The search for better animal models of Alzheimer’s disease

(2018) Anthony King   NATURE

Inflammaging: a new immune–metabolic viewpoint for age-related diseases

(2018) Claudio Franceschi et al.   Nature Reviews Endocrinology

TREM2 — a key player in microglial biology and Alzheimer disease

(2018) Tyler K. Ulland et al.   Nature Reviews Neurology

Mechanisms of Cell-to-Cell Transmission of Pathological Tau

(2018) Garrett S. Gibbons et al.   JAMA Neurology

A nonhuman primate model of early Alzheimer's disease pathologic change: Implications for disease pathogenesis

(2018) Caitlin S. Latimer et al.   Alzheimers & Dementia

Aged chimpanzees exhibit pathologic hallmarks of Alzheimer's disease

(2017) Melissa K. Edler et al.   NEUROBIOLOGY OF AGING

Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer’s Disease

(2017) Hongjun Fu et al.   NEURON

The Exceptional Vulnerability of Humans to Alzheimer’s Disease

(2017) Lary C. Walker et al.   TRENDS IN MOLECULAR MEDICINE

What is the evidence that tau pathology spreads through prion-like propagation?

(2017) Amrit Mudher et al.   Acta Neuropathologica Communications

Alzheimer’s disease: experimental models and reality

(2016) Eleanor Drummond et al.   ACTA NEUROPATHOLOGICA

Glial cell morphological and density changes through the lifespan of rhesus macaques

(2016) Katelyn N. Robillard et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuronal activity enhances tau propagation and tau pathology in vivo

(2016) Jessica W Wu et al.   NATURE NEUROSCIENCE

How neuroinflammation contributes to neurodegeneration

(2016) R. M. Ransohoff   SCIENCE

A Phosphorylation-Induced Turn Defines the Alzheimer’s Disease AT8 Antibody Epitope on the Tau Protein

(2015) Neha S. Gandhi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Estrogen Effects on Cognitive and Synaptic Health Over the Lifecourse

(2015) Yuko Hara et al.   PHYSIOLOGICAL REVIEWS

Propagation of tau pathology in Alzheimer’s disease: identification of novel therapeutic targets

(2013) Amy M Pooler et al.   Alzheimers Research & Therapy

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

(2012) Alix de Calignon et al.   NEURON

Human P301L-Mutant Tau Expression in Mouse Entorhinal-Hippocampal Network Causes Tau Aggregation and Presynaptic Pathology but No Cognitive Deficits

(2012) Julie A. Harris et al.   PLoS One

Estrogen and the aging brain: an elixir for the weary cortical network

(2010) Dani Dumitriu et al.   Annals of the New York Academy of Sciences

Tau in Alzheimer Disease and Related Tauopathies

(2010) K. Iqbal et al.   Current Alzheimer Research

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

(2010) Kaj Blennow et al.   Nature Reviews Neurology

Conformational Changes Specific for Pseudophosphorylation at Serine 262 Selectively Impair Binding of Tau to Microtubules

(2009) Daniela Fischer et al.   BIOCHEMISTRY

Alzheimer-type tau pathology in advanced aged nonhuman primate brains harboring substantial amyloid deposition

(2009) Naoto Oikawa et al.   BRAIN RESEARCH

Intrinsic connections of the macaque monkey hippocampal formation: II. CA3 connections

(2009) Hideki Kondo et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Increased Neurofibrillary Tangles in Patients With Alzheimer Disease With Comorbid Depression

(2008) Michael A. Rapp et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

New insights into brain BDNF function in normal aging and Alzheimer disease

(2008) Lucia Tapia-Arancibia et al.   BRAIN RESEARCH REVIEWS