Rapid pH-responsive self-disintegrating nanoassemblies balance tumor accumulation and penetration for enhanced anti-breast cancer therapy

Near-Infrared Laser-Triggered In Situ Dimorphic Transformation of BF2-Azadipyrromethene Nanoaggregates for Enhanced Solid Tumor Penetration

(2020) Yuanfang Chen et al.   ACS Nano

Facile strategy by hyaluronic acid functional carbon dot-doxorubicin nanoparticles for CD44 targeted drug delivery and enhanced breast cancer therapy

(2020) Jianping Li et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

pH-sensitive pluronic micelles combined with oxidative stress amplification for enhancing multidrug resistance breast cancer therapy

(2020) Xu Cheng et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Tumor Microenvironment Stimuli-Responsive Nanoparticles for Programmed Anticancer Drug Delivery

(2020) Nan Jia et al.   MOLECULAR PHARMACEUTICS

Engineering extracellular matrix to improve drug delivery for cancer therapy

(2020) Xiaocong He et al.   DRUG DISCOVERY TODAY

Tumor microenvironment-induced structure changing drug/gene delivery system for overcoming delivery-associated challenges

(2020) Min Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Dual-pH Sensitive Charge-Reversal Drug Delivery System for Highly Precise and Penetrative Chemotherapy

(2020) Weiguo Chen et al.   PHARMACEUTICAL RESEARCH

Enhancement of tumour penetration by nanomedicines through strategies based on transport processes and barriers

(2020) Huang Yang et al.   JOURNAL OF CONTROLLED RELEASE

Prevention of breast cancer by dietary polyphenols—role of cancer stem cells

(2019) Hao-Feng Gu et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Hyaluronic Acid-Based Activatable Nanomaterials for Stimuli-Responsive Imaging and Therapeutics: Beyond CD44-Mediated Drug Delivery

(2019) Ki Young Choi et al.   ADVANCED MATERIALS

Carbon Dots, Unconventional Preparation Strategies, and Applications Beyond Photoluminescence

(2019) Xue-Tao Tian et al.   Small

Tumor-Associated Fibroblast-Targeted Regulation and Deep Tumor Delivery of Chemotherapeutic Drugs with a Multifunctional Size-Switchable Nanoparticle

(2019) Xingli Cun et al.   ACS Applied Materials & Interfaces

Functional extracellular vesicles engineered with lipid-grafted hyaluronic acid effectively reverse cancer drug resistance

(2019) Jia Liu et al.   BIOMATERIALS

Emerging nanomedicines for anti-stromal therapy against desmoplastic tumors

(2019) Xuexiang Han et al.   BIOMATERIALS

Carboxylated branched poly(β-amino ester) nanoparticles enable robust cytosolic protein delivery and CRISPR-Cas9 gene editing

(2019) Yuan Rui et al.   Science Advances

Targeting tumor hypoxia with stimulus-responsive nanocarriers in overcoming drug resistance and monitoring anticancer efficacy

(2018) Zhiqi Xie et al.   Acta Biomaterialia

Overcoming obstacles in the tumor microenvironment: Recent advancements in nanoparticle delivery for cancer theranostics

(2018) Marta Overchuk et al.   BIOMATERIALS

Strategies to improve tumor penetration of nanomedicines through nanoparticle design

(2018) Ya-Ru Zhang et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

A size switchable nanoplatform for targeting the tumor microenvironment and deep tumor penetration

(2018) Xingli Cun et al.   Nanoscale

A size-shrinkable nanoparticle-based combined anti-tumor and anti-inflammatory strategy for enhanced cancer therapy

(2018) Zhengze Lu et al.   Nanoscale

pH-Sensitive Poly(β-amino ester)s Nanocarriers Facilitate the Inhibition of Drug Resistance in Breast Cancer Cells

(2018) Mengxue Zhou et al.   Nanomaterials

Carbon Dots Embedded Magnetic Nanoparticles @Chitosan @Metal Organic Framework as a Nanoprobe for pH Sensitive Targeted Anticancer Drug Delivery

(2016) Angshuman Ray Chowdhuri et al.   ACS Applied Materials & Interfaces

Ki-67 is a prognostic marker for hormone receptor positive tumors

(2016) M. E. Pérez-López et al.   Clinical & Translational Oncology

Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy

(2016) Hong-Jun Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polymers with tertiary amine groups for drug delivery and bioimaging

(2016) Yu-Juan Gao et al.   Science China-Chemistry

Carbon-Quantum-Dots-Loaded Mesoporous Silica Nanocarriers with pH-Switchable Zwitterionic Surface and Enzyme-Responsive Pore-Cap for Targeted Imaging and Drug Delivery to Tumor

(2016) Zhongning Liu et al.   Advanced Healthcare Materials

Multistage Nanovehicle Delivery System Based on Stepwise Size Reduction and Charge Reversal for Programmed Nuclear Targeting of Systemically Administered Anticancer Drugs

(2015) Lian Li et al.   ADVANCED FUNCTIONAL MATERIALS

A pH-responsive cell-penetrating peptide-modified liposomes with active recognizing of integrin α v β 3 for the treatment of melanoma

(2015) Kairong Shi et al.   JOURNAL OF CONTROLLED RELEASE

Hyaluronic acid–PEI–cyclodextrin polyplexes: implications for in vitro and in vivo transfection efficiency and toxicity

(2015) S. Jain et al.   RSC Advances

Efficient targeted gene delivery by a novel PAMAM/DNA dendriplex coated with hyaluronic acid

(2014) Koldo Urbiola et al.   Nanomedicine

One-pot synthesis of pH-sensitive poly(RGD-co-β-amino ester)s for targeted intracellular drug delivery

(2013) Zeng-Ying Qiao et al.   Polymer Chemistry

Polymer Micelle with pH-Triggered Hydrophobic–Hydrophilic Transition and De-Cross-Linking Process in the Core and Its Application for Targeted Anticancer Drug Delivery

(2012) Jianquan Fan et al.   BIOMACROMOLECULES

Tailor-Made Dual pH-Sensitive Polymer–Doxorubicin Nanoparticles for Efficient Anticancer Drug Delivery

(2011) Jin-Zhi Du et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

(2011) H. Cabral et al.   Nature Nanotechnology

pH-sensitive and bioadhesive poly(β-amino ester)–poly(ethylene glycol)–poly(β-amino ester) triblock copolymer hydrogels with potential for drug delivery in oral mucosal surfaces

(2009) Minh Khanh Nguyen et al.   POLYMER

Di-tert-butyl dicarbonate: a versatile carboxylating reagent

(2008) John Kallikat Augustine et al.   TETRAHEDRON