The role of Piezo1 in conventional aqueous humor outflow dynamics

Measurement of Ocular Compliance Using iPerfusion

(2019) Joseph M. Sherwood et al.   Frontiers in Bioengineering and Biotechnology

Simplifying “target” intraocular pressure for different stages of primary open-angle glaucoma and primary angle-closure glaucoma

(2018) Ramanjit Sihota et al.   INDIAN JOURNAL OF OPHTHALMOLOGY

TREK-1 channels regulate pressure sensitivity and calcium signaling in trabecular meshwork cells

(2018) Oleg Yarishkin et al.   JOURNAL OF GENERAL PHYSIOLOGY

A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression

(2018) Xin Chen et al.   NEURON

Autophagy and mechanotransduction in outflow pathway cells

(2017) Joshua Hirt et al.   EXPERIMENTAL EYE RESEARCH

The role of integrins in glaucoma

(2017) Mark S. Filla et al.   EXPERIMENTAL EYE RESEARCH

Piezo channels and GsMTx4: Two milestones in our understanding of excitatory mechanosensitive channels and their role in pathology

(2017) Thomas M. Suchyna   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Interaction of cochlin and mechanosensitive channel TREK-1 in trabecular meshwork cells influences the regulation of intraocular pressure

(2017) Teresia A. Carreon et al.   Scientific Reports

Piezo2 senses airway stretch and mediates lung inflation-induced apnoea

(2016) Keiko Nonomura et al.   NATURE

Mechanosensing is critical for axon growth in the developing brain

(2016) David E Koser et al.   NATURE NEUROSCIENCE

Piezo1-dependent regulation of urinary osmolarity

(2016) Joana Raquel Martins et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Measurement of Outflow Facility Using iPerfusion

(2016) Joseph M. Sherwood et al.   PLoS One

Caveolin-1 modulates intraocular pressure: implications for caveolae mechanoprotection in glaucoma

(2016) Michael H. Elliott et al.   Scientific Reports

TRPV4 regulates calcium homeostasis, cytoskeletal remodeling, conventional outflow and intraocular pressure in the mammalian eye

(2016) Daniel A. Ryskamp et al.   Scientific Reports

Piezo2 is the principal mechanotransduction channel for proprioception

(2015) Seung-Hyun Woo et al.   NATURE NEUROSCIENCE

Mechanically Activated Ion Channels

(2015) Sanjeev S. Ranade et al.   NEURON

Biomechanics of Schlemm's canal endothelium and intraocular pressure reduction

(2015) W. Daniel Stamer et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia

(2015) Viktor Lukacs et al.   Nature Communications

TMC1 and TMC2 Localize at the Site of Mechanotransduction in Mammalian Inner Ear Hair Cell Stereocilia

(2015) Kiyoto Kurima et al.   Cell Reports

Piezo1 in Smooth Muscle Cells Is Involved in Hypertension-Dependent Arterial Remodeling

(2015) Kevin Retailleau et al.   Cell Reports

Chemical activation of the mechanotransduction channel Piezo1

(2015) Ruhma Syeda et al.   eLife

Piezo1 links mechanical forces to red blood cell volume

(2015) Stuart M Cahalan et al.   eLife

Merkel Cells Transduce and Encode Tactile Stimuli to Drive Aβ-Afferent Impulses

(2014) Ryo Ikeda et al.   CELL

The Pathophysiology and Treatment of Glaucoma

(2014) Robert N. Weinreb et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Piezo2 is the major transducer of mechanical forces for touch sensation in mice

(2014) Sanjeev S. Ranade et al.   NATURE

Piezo2 is required for Merkel-cell mechanotransduction

(2014) Seung-Hyun Woo et al.   NATURE

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells

(2014) Medha M. Pathak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage

(2014) Whasil Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanotransduction Channels of the Trabecular Meshwork

(2013) Vu T. Tran et al.   CURRENT EYE RESEARCH

Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis

(2013) B. Coste et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for Piezo2 in EPAC1-dependent mechanical allodynia

(2013) N Eijkelkamp et al.   Nature Communications

Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia

(2012) George T. Eisenhoffer et al.   NATURE

Mechano-regulation of the beating heart at the cellular level – Mechanosensitive channels in normal and diseased heart

(2012) Oliver Friedrich et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

The Mechanosensitive Ion Channel Piezo1 Is Inhibited by the Peptide GsMTx4

(2011) Chilman Bae et al.   BIOCHEMISTRY

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Stress Response of the Trabecular Meshwork

(2009) Paloma B. Liton et al.   JOURNAL OF GLAUCOMA

Mechanosensitive TRP channels in cardiovascular pathophysiology

(2009) Ryuji Inoue et al.   PHARMACOLOGY & THERAPEUTICS

Mechanobiology of trabecular meshwork cells

(2008) Darrell WuDunn   EXPERIMENTAL EYE RESEARCH

Progressive Ganglion Cell Degeneration Precedes Neuronal Loss in a Mouse Model of Glaucoma

(2008) B. P. Buckingham et al.   JOURNAL OF NEUROSCIENCE