Reversing cold tumors to hot: An immunoadjuvant-functionalized metal-organic framework for multimodal imaging-guided synergistic photo-immunotherapy

Rationally Designed Polymer Conjugate for Tumor-Specific Amplification of Oxidative Stress and Boosting Antitumor Immunity

(2020) Sheng Ma et al.   NANO LETTERS

Equipping Natural Killer Cells with Specific Targeting and Checkpoint Blocking Aptamers for Enhanced Adoptive Immunotherapy in Solid Tumors

(2020) Da Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Antifouling Strategies for Selective In Vitro and In Vivo Sensing

(2020) Cheng Jiang et al.   CHEMICAL REVIEWS

Tumor microenvironment-activated self-recognizing nanodrug through directly tailored assembly of small-molecules for targeted synergistic chemotherapy

(2020) Yang Li et al.   JOURNAL OF CONTROLLED RELEASE

Nanoscale Metal–Organic Framework Co-delivers TLR-7 Agonists and Anti-CD47 Antibodies to Modulate Macrophages and Orchestrate Cancer Immunotherapy

(2020) Kaiyuan Ni et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Converting Immune Cold into Hot by Biosynthetic Functional Vesicles to Boost Systematic Antitumor Immunity

(2020) Ming Wu et al.   iScience

High-affinity mutant Interleukin-13 targeted CAR T cells enhance delivery of clickable biodegradable fluorescent nanoparticles to glioblastoma

(2020) Gloria B. Kim et al.   Bioactive Materials

Ultrathin Tellurium Oxide/Ammonium Tungsten Bronze Nanoribbon for Multimodality Imaging and Second Near-Infrared Region Photothermal Therapy

(2019) Yaru Cheng et al.   NANO LETTERS

Nanoparticle‐Based Nanomedicines to Promote Cancer Immunotherapy: Recent Advances and Future Directions

(2019) Jianping Liu et al.   Small

A Mn(III)-Sealed Metal-Organic Framework Nanosystem for Redox-Unlocked Tumor Theranostics

(2019) Shuang-Shuang Wan et al.   ACS Nano

A Mesoporous Nanoenzyme Derived from Metal–Organic Frameworks with Endogenous Oxygen Generation to Alleviate Tumor Hypoxia for Significantly Enhanced Photodynamic Therapy

(2019) Dongdong Wang et al.   ADVANCED MATERIALS

Synergistic Amplification of Oxidative Stress–Mediated Antitumor Activity via Liposomal Dichloroacetic Acid and MOF‐Fe 2+

(2019) Lei Sun et al.   Small

Cancer nanomedicine for combination cancer immunotherapy

(2019) Jutaek Nam et al.   Nature Reviews Materials

Cancer-Cell-Activated Photodynamic Therapy Assisted by Cu(II)-Based Metal–Organic Framework

(2019) Yuanbo Wang et al.   ACS Nano

Targeting photodynamic and photothermal therapy to the endoplasmic reticulum enhances immunogenic cancer cell death

(2019) Wei Li et al.   Nature Communications

Exploiting Single Atom Iron Centers in a Porphyrin-like MOF for Efficient Cancer Phototherapy

(2019) Li Wang et al.   ACS Applied Materials & Interfaces

NK-Cell-Encapsulated Porous Microspheres via Microfluidic Electrospray for Tumor Immunotherapy

(2019) Dan Wu et al.   ACS Applied Materials & Interfaces

Nanoscale Coordination Polymer Based Nanovaccine for Tumor Immunotherapy

(2019) He Zhao et al.   ACS Nano

Tumor Microenvironment Responsive Shape-Reversal Self-Targeting Virus-Inspired Nanodrug for Imaging-Guided Near-Infrared-II Photothermal Chemotherapy

(2019) Yang Li et al.   ACS Nano

NIR/ROS‐Responsive Black Phosphorus QD Vesicles as Immunoadjuvant Carrier for Specific Cancer Photodynamic Immunotherapy

(2019) Zhi Li et al.   ADVANCED FUNCTIONAL MATERIALS

Tumor‐Targeted Drug and CpG Delivery System for Phototherapy and Docetaxel‐Enhanced Immunotherapy with Polarization toward M1‐Type Macrophages on Triple Negative Breast Cancers

(2019) Lv Chen et al.   ADVANCED MATERIALS

A Nanoscale Metal-Organic Framework to Mediate Photodynamic Therapy and Deliver CpG Oligodeoxynucleotides to Enhance Antigen Presentation and Cancer Immunotherapy

(2019) Kaiyuan Ni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanoscale metal-organic frameworks and coordination polymers as theranostic platforms for cancer treatment

(2019) Wenjun Zhu et al.   COORDINATION CHEMISTRY REVIEWS

Hybrid Protein Nano‐Reactors Enable Simultaneous Increments of Tumor Oxygenation and Iodine‐131 Delivery for Enhanced Radionuclide Therapy

(2019) Jiawen Chen et al.   Small

Functionalized DNA Enables Programming Exosomes/Vesicles for Tumor Imaging and Therapy

(2019) Zhijin Fan et al.   Small

Targeting and Specific Activation of Antigen‐Presenting Cells by Endogenous Antigen‐Loaded Nanoparticles Elicits Tumor‐Specific Immunity

(2019) Hao‐Cai Chang et al.   Advanced Science

Radiosensitive core/satellite ternary heteronanostructure for multimodal imaging-guided synergistic cancer radiotherapy

(2019) Hongxing Liu et al.   BIOMATERIALS

In Vivo Monocyte/Macrophage-Hitchhiked Intratumoral Accumulation of Nanomedicines for Enhanced Tumor Therapy

(2019) Liyan Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reduction-Responsive Codelivery System Based on a Metal–Organic Framework for Eliciting Potent Cellular Immune Response

(2018) Yong Yang et al.   ACS Applied Materials & Interfaces

Photothermal-Activatable Fe3O4 Superparticle Nanodrug Carriers with PD-L1 Immune Checkpoint Blockade for Anti-metastatic Cancer Immunotherapy

(2018) Rui Ge et al.   ACS Applied Materials & Interfaces

Nanoscale Metal-Organic Frameworks for Therapeutic, Imaging, and Sensing Applications

(2018) Kuangda Lu et al.   ADVANCED MATERIALS

Active droplet-array (ADA) microfluidics enables multiplexed complex bioassays for point of care testing

(2018) Bowen Shu et al.   CHEMICAL COMMUNICATIONS

Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges

(2018) Dai Fukumura et al.   Nature Reviews Clinical Oncology

M1 Macrophage-Derived Nanovesicles Potentiate the Anticancer Efficacy of Immune Checkpoint Inhibitors

(2018) Yeon Woong Choo et al.   ACS Nano

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

NKG2A Blockade Potentiates CD8 T Cell Immunity Induced by Cancer Vaccines

(2018) Nadine van Montfoort et al.   CELL

Building a better lymphoma vaccine

(2018) Claire Ainsworth   NATURE

A framework for the development of effective anti-metastatic agents

(2018) Robin L. Anderson et al.   Nature Reviews Clinical Oncology

Multivariate Metal–Organic Frameworks for Dialing-in the Binding and Programming the Release of Drug Molecules

(2017) Zhiyue Dong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cancer immunotherapy

(2017) Eric Bender   NATURE

Chimeric Antigen Receptor-Engineered NK-92 Cells: An Off-the-Shelf Cellular Therapeutic for Targeted Elimination of Cancer Cells and Induction of Protective Antitumor Immunity

(2017) Congcong Zhang et al.   Frontiers in Immunology

Microwave pumped high-efficient thermoacoustic tumor therapy with single wall carbon nanotubes

(2016) Liewei Wen et al.   BIOMATERIALS

Cancer treatment and survivorship statistics, 2016

(2016) Kimberly D. Miller et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade

(2016) Joseph L. Benci et al.   CELL

Photo-enhancement of macrophage phagocytic activity via Rac1-mediated signaling pathway: Implications for bacterial infection

(2016) Cuixia Lu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Acid-Activatable Versatile Micelleplexes for PD-L1 Blockade-Enhanced Cancer Photodynamic Immunotherapy

(2016) Dangge Wang et al.   NANO LETTERS

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

(2016) N. McGranahan et al.   SCIENCE

Macrophage engulfment of a cell or nanoparticle is regulated by unavoidable opsonization, a species-specific ‘Marker of Self’ CD47, and target physical properties

(2015) Nisha G Sosale et al.   CURRENT OPINION IN IMMUNOLOGY

Chemo/Photoacoustic Dual Therapy with mRNA-Triggered DOX Release and Photoinduced Shockwave Based on a DNA-Gold Nanoplatform

(2015) Yundong Zang et al.   Small

Characterization of Lipid-Rich Aortic Plaques by Intravascular Photoacoustic Tomography

(2014) Jian Zhang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

(2013) Cosimo Commisso et al.   NATURE

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE

Postsynthetic Modifications of Iron-Carboxylate Nanoscale Metal−Organic Frameworks for Imaging and Drug Delivery

(2009) Kathryn M. L. Taylor-Pashow et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High-Throughput Assisted Rationalization of the Formation of Metal Organic Frameworks in the Iron(III) Aminoterephthalate Solvothermal System

(2008) Sebastian Bauer et al.   INORGANIC CHEMISTRY