NADPH and Mito-Apocynin Treatment Protects Against KA-Induced Excitotoxic Injury Through Autophagy Pathway

NADPH protects against kainic acid-induced excitotoxicity via autophagy-lysosome pathway in rat striatum and primary cortical neurons

(2020) Zi-Qi Liu et al.   TOXICOLOGY

Cytoplasmic and Mitochondrial NADPH-Coupled Redox Systems in the Regulation of Aging

(2019) Patrick Bradshaw   Nutrients

STIM Proteins and Glutamate Receptors in Neurons: Role in Neuronal Physiology and Neurodegenerative Diseases

(2019) Karolina Serwach et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of NADPH oxidase-2 in the progression of the inflammatory response secondary to striatum excitotoxic damage

(2019) Diego Rolando Hernández-Espinosa et al.   Journal of Neuroinflammation

TIGAR alleviates ischemia/reperfusion-induced autophagy and ischemic brain injury

(2019) Ding-Mei Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

The interplay between redox signalling and proteostasis in neurodegeneration: In vivo effects of a mitochondria-targeted antioxidant in Huntington's disease mice

(2019) Brígida R. Pinho et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sensory representations in the striatum provide a temporal reference for learning and executing motor habits

(2019) Ana E. Hidalgo-Balbuena et al.   Nature Communications

NADPH metabolism: a survey of its theoretical characteristics and manipulation strategies in amino acid biosynthesis

(2018) Jian-Zhong Xu et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Glutamatergic Signaling in the Central Nervous System: Ionotropic and Metabotropic Receptors in Concert

(2018) Andreas Reiner et al.   NEURON

The diverse role of TIGAR in cellular homeostasis and cancer

(2018) Ji Geng et al.   FREE RADICAL RESEARCH

Combined NADPH and the NOX inhibitor apocynin provides greater anti-inflammatory and neuroprotective effects in a mouse model of stroke

(2017) Yuan-Yuan Qin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death

(2017) Ajit S. Divakaruni et al.   JOURNAL OF CELL BIOLOGY

Combination of NAD+ and NADPH Offers Greater Neuroprotection in Ischemic Stroke Models by Relieving Metabolic Stress

(2017) Qiao Huang et al.   MOLECULAR NEUROBIOLOGY

NADPH oxidase in brain injury and neurodegenerative disorders

(2017) Merry W. Ma et al.   Molecular Neurodegeneration

Neuronal protection against oxidative insult by polyanhydride nanoparticle-based mitochondria-targeted antioxidant therapy

(2017) Timothy M. Brenza et al.   Nanomedicine-Nanotechnology Biology and Medicine

Transcriptional Regulation by Nrf2

(2017) Claudia Tonelli et al.   ANTIOXIDANTS & REDOX SIGNALING

Glutamate excitotoxicity and Ca 2+ -regulation of respiration: Role of the Ca 2+ activated mitochondrial transporters (CaMCs)

(2016) Carlos B. Rueda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitoapocynin Treatment Protects Against Neuroinflammation and Dopaminergic Neurodegeneration in a Preclinical Animal Model of Parkinson’s Disease

(2016) Anamitra Ghosh et al.   Journal of Neuroimmune Pharmacology

PINK1 in the limelight: multiple functions of an eclectic protein in human health and disease

(2016) Giuseppe Arena et al.   JOURNAL OF PATHOLOGY

Intake of antioxidant vitamins and risk of Parkinson's disease

(2016) Katherine C. Hughes et al.   MOVEMENT DISORDERS

ROS and Autophagy: Interactions and Molecular Regulatory Mechanisms

(2015) Lulu Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

The emerging role of Nrf2 in mitochondrial function

(2015) Albena T. Dinkova-Kostova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reduced Nicotinamide Adenine Dinucleotide Phosphate, a Pentose Phosphate Pathway Product, Might Be a Novel Drug Candidate for Ischemic Stroke

(2015) Mei Li et al.   STROKE

Glutamatergic Mechanisms Associated with Seizures and Epilepsy

(2015) Melissa Barker-Haliski et al.   Cold Spring Harbor Perspectives in Medicine

Reactive oxygen species and mitochondria: A nexus of cellular homeostasis

(2015) Joe Dan Dunn et al.   Redox Biology

An autophagic mechanism is involved in apoptotic death of rat striatal neurons induced by the non-N-methyl-D-aspartate receptor agonist kainic acid

(2014) Yan Wang et al.   Autophagy

Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells

(2014) Caroline A. Lewis et al.   MOLECULAR CELL

A novel mitochondrially-targeted apocynin derivative prevents hyposmia and loss of motor function in the leucine-rich repeat kinase 2 (LRRK2R1441G) transgenic mouse model of Parkinson's disease

(2014) Brian P. Dranka et al.   NEUROSCIENCE LETTERS

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

(2013) Ted Weita Lai et al.   PROGRESS IN NEUROBIOLOGY

Molecular and cellular mechanisms of excitotoxic neuronal death

(2010) Yan Wang et al.   APOPTOSIS

Regulation of autophagy by ROS: physiology and pathology

(2010) Ruth Scherz-Shouval et al.   TRENDS IN BIOCHEMICAL SCIENCES

Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases

(2009) Xiao-xia Dong et al.   ACTA PHARMACOLOGICA SINICA

p53 mediates mitochondria dysfunction-triggered autophagy activation and cell death in rat striatum

(2009) Xing-Ding Zhang et al.   Autophagy

p53 induction contributes to excitotoxic neuronal death in rat striatum through apoptotic and autophagic mechanisms

(2009) Yan Wang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

NAD+/NADH and NADP+/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences

(2007) Weihai Ying   ANTIOXIDANTS & REDOX SIGNALING