GIP mediates the incretin effect and glucose tolerance by dual actions on α cells and β cells

Alanine, arginine, cysteine, and proline but not glutamine are substrates for and acute mediators of the liver-alpha cell axis in female mice

(2020) Katrine D. Galsgaard et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Discordance between GLP-1R gene and protein expression in mouse pancreatic islet cells

(2020) Sarah M Gray et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Repositioning the Alpha Cell in Postprandial Metabolism

(2020) Kimberley El et al.   ENDOCRINOLOGY

Separate and Combined Gluco-Metabolic Effects of Endogenous Glucose-Dependent Insulinotropic Polypeptide and Glucagon-Like Peptide-1 in Healthy Individuals

(2019) Lærke S. Gasbjerg et al.   DIABETES

The incretin system in healthy humans: The role of GIP and GLP-1

(2019) Jens Juul Holst   METABOLISM-CLINICAL AND EXPERIMENTAL

Gut-Proglucagon-Derived Peptides Are Essential for Regulating Glucose Homeostasis in Mice

(2019) Youngmi Song et al.   Cell Metabolism

The role of GIP in α-cells and glucagon secretion

(2019) Kimberley El et al.   PEPTIDES

Advances in oral peptide therapeutics

(2019) Daniel J. Drucker   NATURE REVIEWS DRUG DISCOVERY

Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point

(2018) Rayner Rodriguez-Diaz et al.   Cell Metabolism

Interrogating the Spatiotemporal Landscape of Neuromodulatory GPCR Signaling by Real-Time Imaging of cAMP in Intact Neurons and Circuits

(2018) Brian S. Muntean et al.   Cell Reports

Insulin Secretion Depends on Intra-islet Glucagon Signaling

(2018) Berit Svendsen et al.   Cell Reports

High-fidelity Glucagon-CreER mouse line generated by CRISPR-Cas9 assisted gene targeting

(2017) Amanda M. Ackermann et al.   Molecular Metabolism

Is GLP-1 a hormone: Whether and When?

(2016) David D'Alessio   Journal of Diabetes Investigation

The incretin effect in healthy individuals and those with type 2 diabetes: physiology, pathophysiology, and response to therapeutic interventions

(2016) Michael A Nauck et al.   Lancet Diabetes & Endocrinology

Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets

(2016) Michael R. DiGruccio et al.   Molecular Metabolism

TCF1 links GIPR signaling to the control of beta cell function and survival

(2015) Jonathan E Campbell et al.   NATURE MEDICINE

Transgenic Mice for Intersectional Targeting of Neural Sensors and Effectors with High Specificity and Performance

(2015) Linda Madisen et al.   NEURON

The Role of β Cell Glucagon-like Peptide-1 Signaling in Glucose Regulation and Response to Diabetes Drugs

(2014) Eric P. Smith et al.   Cell Metabolism

GIP Contributes to Islet Trihormonal Abnormalities in Type 2 Diabetes

(2014) Chee W. Chia et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Pharmacology, Physiology, and Mechanisms of Incretin Hormone Action

(2013) Jonathan E. Campbell et al.   Cell Metabolism

Liver-Specific Disruption of the Murine Glucagon Receptor Produces  -Cell Hyperplasia: Evidence for a Circulating  -Cell Growth Factor

(2012) C. Longuet et al.   DIABETES

The separate and combined impact of the intestinal hormones, GIP, GLP-1, and GLP-2, on glucagon secretion in type 2 diabetes

(2011) Asger Lund et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Glucose-Dependent Insulinotropic Polypeptide: A Bifunctional Glucose-Dependent Regulator of Glucagon and Insulin Secretion in Humans

(2011) M. Christensen et al.   DIABETES

S961, an insulin receptor antagonist causes hyperinsulinemia, insulin-resistance and depletion of energy stores in rats

(2010) Ajit Vikram et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Exogenous Glucose-Dependent Insulinotropic Polypeptide Worsens Post prandial Hyperglycemia in T ype 2 Diabetes

(2009) C. W. Chia et al.   DIABETES