Longitudinal antibody repertoire in “mild” versus “severe” COVID-19 patients reveals immune markers associated with disease severity and resolution

Longitudinal Human Antibody Repertoire against Complete Viral Proteome from Ebola Virus Survivor Reveals Protective Sites for Vaccine Design

(2020) Surender Khurana et al.   Cell Host & Microbe

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies

(2020) Daniel Wrapp et al.   CELL

A Sequence Homology and Bioinformatic Approach Can Predict Candidate Targets for Immune Responses to SARS-CoV-2

(2020) Alba Grifoni et al.   Cell Host & Microbe

Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure

(2020) Evangelos J. Giamarellos-Bourboulis et al.   Cell Host & Microbe

Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

(2020) Shuai Xia et al.   CELL RESEARCH

Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019

(2020) Juanjuan Zhao et al.   CLINICAL INFECTIOUS DISEASES

Immunology of COVID-19: current state of the science

(2020) Nicolas Vabret et al.   IMMUNITY

Convalescent Plasma to Treat COVID-19

(2020) John D. Roback et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study

(2020) Kelvin Kai-Wang To et al.   LANCET INFECTIOUS DISEASES

Viral and host factors related to the clinical outcome of COVID-19

(2020) Xiaonan Zhang et al.   NATURE

The race for coronavirus vaccines: a graphical guide

(2020) Ewen Callaway   NATURE

Virological assessment of hospitalized patients with COVID-2019

(2020) Roman Wölfel et al.   NATURE

Rapid COVID-19 vaccine development

(2020) Barney S. Graham   SCIENCE

Serology for SARS-CoV-2: Apprehensions, opportunities, and the path forward

(2020) Juliet E. Bryant et al.   Science Immunology

Neutralizing Antibody Responses to Severe Acute Respiratory Syndrome Coronavirus 2 in Coronavirus Disease 2019 Inpatients and Convalescent Patients

(2020) Xiaoli Wang et al.   CLINICAL INFECTIOUS DISEASES

Development of Genetic Diagnostic Methods for Detection for Novel Coronavirus 2019(nCoV-2019) in Japan

(2020) Kazuya Shirato et al.   JAPANESE JOURNAL OF INFECTIOUS DISEASES

An mRNA Vaccine against SARS-CoV-2 — Preliminary Report

(2020) Lisa A. Jackson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

(2020) Divij Mathew et al.   SCIENCE

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

(2020) Philip J. M. Brouwer et al.   SCIENCE

Antibody signature induced by SARS-CoV-2 spike protein immunogens in rabbits

(2020) Supriya Ravichandran et al.   Science Translational Medicine

Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19

(2020) Naoki Kaneko et al.   CELL

Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients

(2020) Christoph Kreer et al.   CELL

SARS-CoV-2 viral load and antibody responses: the case for convalescent plasma therapy

(2020) Arturo Casadevall et al.   JOURNAL OF CLINICAL INVESTIGATION

SARS-CoV-2 Neutralizing Antibody LY-CoV555 in Outpatients with Covid-19

(2020) Peter Chen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Differential human antibody repertoires following Zika infection and the implications for serodiagnostics and disease outcome

(2019) Supriya Ravichandran et al.   Nature Communications

Repeat vaccination reduces antibody affinity maturation across different influenza vaccine platforms in humans

(2019) Surender Khurana et al.   Nature Communications

Anti-influenza hyperimmune intravenous immunoglobulin for adults with influenza A or B infection (FLU-IVIG): a double-blind, randomised, placebo-controlled trial

(2019) Richard T Davey et al.   Lancet Respiratory Medicine

Human antibody repertoire after VSV-Ebola vaccination identifies novel targets and virus-neutralizing IgM antibodies

(2016) Surender Khurana et al.   NATURE MEDICINE

Antigenic Fingerprinting following Primary RSV Infection in Young Children Identifies Novel Antigenic Sites and Reveals Unlinked Evolution of Human Antibody Repertoires to Fusion and Attachment Glycoproteins

(2016) Sandra Fuentes et al.   PLoS Pathogens

H5 N-terminal β sheet promotes oligomerization of H7-HA1 that induces better antibody affinity maturation and enhanced protection against H7N7 and H7N9 viruses compared to inactivated influenza vaccine

(2014) Surender Khurana et al.   VACCINE

H5N1-SeroDetect EIA and Rapid Test: a Novel Differential Diagnostic Assay for Serodiagnosis of H5N1 Infections and Surveillance

(2011) S. Khurana et al.   JOURNAL OF VIROLOGY

MF59 Adjuvant Enhances Diversity and Affinity of Antibody-Mediated Immune Response to Pandemic Influenza Vaccines

(2011) S. Khurana et al.   Science Translational Medicine

Vaccines with MF59 Adjuvant Expand the Antibody Repertoire to Target Protective Sites of Pandemic Avian H5N1 Influenza Virus

(2010) S. Khurana et al.   Science Translational Medicine

Antigenic Fingerprinting of H5N1 Avian Influenza Using Convalescent Sera and Monoclonal Antibodies Reveals Potential Vaccine and Diagnostic Targets

(2009) Surender Khurana et al.   PLOS MEDICINE