Insulin signaling in AgRP neurons regulates meal size to limit glucose excursions and insulin resistance

NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons

(2020) Linda Engström Ruud et al.   Nature Communications

Leptin Signaling in the Arcuate Nucleus Reduces Insulin’s Capacity to Suppress Hepatic Glucose Production in Obese Mice

(2019) Eglantine Balland et al.   Cell Reports

Sustained NPY signaling enables AgRP neurons to drive feeding

(2019) Yiming Chen et al.   eLife

Natural and Drug Rewards Engage Distinct Pathways that Converge on Coordinated Hypothalamic and Reward Circuits

(2019) Amber L. Alhadeff et al.   NEURON

Intranasal Targeting of Hypothalamic PTP1B and TCPTP Reinstates Leptin and Insulin Sensitivity and Promotes Weight Loss in Obesity

(2019) Garron T. Dodd et al.   Cell Reports

Hypothalamic neuronal circuits regulating hunger-induced taste modification

(2019) Ou Fu et al.   Nature Communications

TCPTP Regulates Insulin Signaling in AgRP Neurons to Coordinate Glucose Metabolism With Feeding

(2018) Garron T. Dodd et al.   DIABETES

Leptin and the maintenance of elevated body weight

(2018) Warren W. Pan et al.   NATURE REVIEWS NEUROSCIENCE

Genetic identification of leptin neural circuits in energy and glucose homeostases

(2018) Jie Xu et al.   NATURE

Insulin regulates POMC neuronal plasticity to control glucose metabolism

(2018) Garron T Dodd et al.   eLife

Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC

(2018) Marcus Grohmann et al.   CELL

AgRP Neurons Can Increase Food Intake during Conditions of Appetite Suppression and Inhibit Anorexigenic Parabrachial Neurons

(2017) Rachel A. Essner et al.   JOURNAL OF NEUROSCIENCE

Food Seeking in a Risky Environment: A Method for Evaluating Risk and Reward Value in Food Seeking and Consumption in Mice

(2017) Sarah H. Lockie et al.   Frontiers in Neuroscience

AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue

(2016) Sophie M. Steculorum et al.   CELL

An Emerging Technology Framework for the Neurobiology of Appetite

(2016) Scott M. Sternson et al.   Cell Metabolism

Parabrachial CGRP Neurons Control Meal Termination

(2016) Carlos A. Campos et al.   Cell Metabolism

Hypothalamic Agrp Neurons Drive Stereotypic Behaviors beyond Feeding

(2015) Marcelo O. Dietrich et al.   CELL

Leptin and Insulin Act on POMC Neurons to Promote the Browning of White Fat

(2015) Garron T. Dodd et al.   CELL

Palatability Can Drive Feeding Independent of AgRP Neurons

(2015) Raphaël G.P. Denis et al.   Cell Metabolism

Neurons for hunger and thirst transmit a negative-valence teaching signal

(2015) J. Nicholas Betley et al.   NATURE

Whole-brain mapping of the direct inputs and axonal projections of POMC and AgRP neurons

(2015) Daqing Wang et al.   Frontiers in Neuroanatomy

Ablation of AgRP neurons impairs adaption to restricted feeding

(2014) Keith Tan et al.   Molecular Metabolism

Parallel, Redundant Circuit Organization for Homeostatic Control of Feeding Behavior

(2013) J. Nicholas Betley et al.   CELL

Rapid versus Delayed Stimulation of Feeding by the Endogenously Released AgRP Neuron Mediators GABA, NPY, and AgRP

(2013) Michael J. Krashes et al.   Cell Metabolism

Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding

(2013) N. Turner et al.   DIABETOLOGIA

Postprandial Administration of Intranasal Insulin Intensifies Satiety and Reduces Intake of Palatable Snacks in Women

(2012) M. Hallschmid et al.   DIABETES

Deconstruction of a neural circuit for hunger

(2012) Deniz Atasoy et al.   NATURE

AgRP neurons regulate development of dopamine neuronal plasticity and nonfood-associated behaviors

(2012) Marcelo O Dietrich et al.   NATURE NEUROSCIENCE

Rapid, reversible activation of AgRP neurons drives feeding behavior in mice

(2011) Michael J. Krashes et al.   JOURNAL OF CLINICAL INVESTIGATION

AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training

(2011) Yexica Aponte et al.   NATURE NEUROSCIENCE

Direct Insulin and Leptin Action on Pro-opiomelanocortin Neurons Is Required for Normal Glucose Homeostasis and Fertility

(2010) Jennifer W. Hill et al.   Cell Metabolism

Segregation of Acute Leptin and Insulin Effects in Distinct Populations of Arcuate Proopiomelanocortin Neurons

(2010) K. W. Williams et al.   JOURNAL OF NEUROSCIENCE

Evaluation of the lack of anorectic effect of intracerebroventricular insulin in rats

(2009) Lene Jessen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Glucose Metabolism In Vivo in Four Commonly Used Inbred Mouse Strains

(2008) E. D. Berglund et al.   DIABETES

Differential Sensitivity of Men and Women to Anorexigenic and Memory-Improving Effects of Intranasal Insulin

(2008) Christian Benedict et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Collective and Individual Functions of Leptin Receptor Modulated Neurons Controlling Metabolism and Ingestion

(2007) Esther van de Wall et al.   ENDOCRINOLOGY

Specific Physiological Roles for Signal Transducer and Activator of Transcription 3 in Leptin Receptor-Expressing Neurons

(2007) Merisa L. Piper et al.   MOLECULAR ENDOCRINOLOGY