4.7 Article

Threshold conditions for global stability of disease free state of COVID-19

期刊

RESULTS IN PHYSICS
卷 21, 期 -, 页码 -

出版社

ELSEVIER
DOI: 10.1016/j.rinp.2020.103784

关键词

Mathematical model; Basic reproduction number; Next generation matrix; Sensitivity analysis; Global stability; Threshold condition

资金

  1. ICRIOS Bocconi University
  2. Decisions LAB - University Mediterranea of Reggio Calabria, Italy [2/2020]

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This article focuses on the elimination and control of infections caused by COVID-19, formulating mathematical models of the disease and identifying the most sensitive parameters for transmission through sensitivity analysis of the reproduction number. Strategies for controlling the infection are proposed based on these findings, and the threshold condition for global stability of the disease-free state is investigated. Numerical simulations using Matlab validate the theoretical results presented in the study.
This article focus the elimination and control of the infection caused by COVID-19. Mathematical model of the disease is formulated. With help of sensitivity analysis of the reproduction number the most sensitive parameters regarding transmission of infection are found. Consequently strategies for the control of infection are proposed. Threshold condition for global stability of the disease free state is investigated. Finally, using Matlab numerical simulations are produced for validation of theocratical results.

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