Base-modified aptamers obtained by cell-internalization SELEX facilitate cellular uptake of an antisense oligonucleotide

Imaging small molecule-induced endosomal escape of siRNA

(2020) Hampus Du Rietz et al.   Nature Communications

An in Vitro Selection Strategy Identifying Naked DNA That Localizes to Cell Nuclei

(2019) John Smestad et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Golgi-endosome transport mediated by M6PR facilitates release of antisense oligonucleotides from endosomes

(2019) Xue-hai Liang et al.   NUCLEIC ACIDS RESEARCH

The Discovery of RNA Aptamers that Selectively Bind Glioblastoma Stem Cells

(2019) Alessandra Affinito et al.   Molecular Therapy-Nucleic Acids

Development of a Novel DNA Oligonucleotide Targeting Low-Density Lipoprotein Receptor

(2019) Tao Wang et al.   Molecular Therapy-Nucleic Acids

Crystal structures of thrombin in complex with chemically modified thrombin DNA aptamers reveal the origins of enhanced affinity

(2018) Rafal Dolot et al.   NUCLEIC ACIDS RESEARCH

Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines

(2018) David Porciani et al.   Nature Communications

AptaSUITE: A Full-Featured Bioinformatics Framework for the Comprehensive Analysis of Aptamers from HT-SELEX Experiments

(2018) Jan Hoinka et al.   Molecular Therapy-Nucleic Acids

COPII vesicles can affect the activity of antisense oligonucleotides by facilitating the release of oligonucleotides from endocytic pathways

(2018) Xue-hai Liang et al.   NUCLEIC ACIDS RESEARCH

Targeted delivery of antisense oligonucleotides to pancreatic β-cells

(2018) C. Ämmälä et al.   Science Advances

Genetic Alphabet Expansion Provides Versatile Specificities and Activities of Unnatural-Base DNA Aptamers Targeting Cancer Cells

(2018) Kazunobu Futami et al.   Molecular Therapy-Nucleic Acids

Chemical Modifications of Nucleic Acid Aptamers for Therapeutic Purposes

(2017) Shuaijian Ni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cellular uptake and trafficking of antisense oligonucleotides

(2017) Stanley T Crooke et al.   NATURE BIOTECHNOLOGY

Structural basis for IL-1α recognition by a modified DNA aptamer that specifically inhibits IL-1α signaling

(2017) Xiaoming Ren et al.   Nature Communications

Building a chimera of aptamer–antisense oligonucleotide for silencing galectin-1 gene

(2016) Shanni Hong et al.   RSC Advances

Aptamer–Drug Conjugates

(2015) Guizhi Zhu et al.   BIOCONJUGATE CHEMISTRY

Evolution of Functional Six-Nucleotide DNA

(2015) Liqin Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

FASTAptamer: A Bioinformatic Toolkit for High-throughput Sequence Analysis of Combinatorial Selections

(2015) Khalid K Alam et al.   Molecular Therapy-Nucleic Acids

Antibody-Drug Conjugates: An Emerging Concept in Cancer Therapy

(2014) Ravi V. J. Chari et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Development of lipid nanoparticle formulations of siRNA for hepatocyte gene silencing following subcutaneous administration

(2014) Sam Chen et al.   JOURNAL OF CONTROLLED RELEASE

Multifunctional Aptamer-miRNA Conjugates for Targeted Cancer Therapy

(2014) Carla L Esposito et al.   MOLECULAR THERAPY

Targeted delivery of antisense oligonucleotides to hepatocytes using triantennaryN-acetyl galactosamine improves potency 10-fold in mice

(2014) Thazha P. Prakash et al.   NUCLEIC ACIDS RESEARCH

In vitro selection with artificial expanded genetic information systems

(2013) K. Sefah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Liposomal drug delivery systems: From concept to clinical applications

(2012) Theresa M. Allen et al.   ADVANCED DRUG DELIVERY REVIEWS

Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers

(2012) Kristina W. Thiel et al.   NUCLEIC ACIDS RESEARCH

Rapid Identification of Cell-Specific, Internalizing RNA Aptamers with Bioinformatics Analyses of a Cell-Based Aptamer Selection

(2012) William H. Thiel et al.   PLoS One

Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery

(2011) Larry Gold et al.   PLoS One

Targeted Delivery of siRNA to Hepatocytes and Hepatic Stellate Cells by Bioconjugation

(2010) Lin Zhu et al.   BIOCONJUGATE CHEMISTRY

Endosomal escape pathways for delivery of biologicals

(2010) Amir K. Varkouhi et al.   JOURNAL OF CONTROLLED RELEASE

Expanding the Chemistry of DNA for in Vitro Selection

(2010) Jonathan D. Vaught et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY