Repeat-Driven Generation of Antigenic Diversity in a Major Human Pathogen, Trypanosoma cruzi

Mechanisms of DNA repair in Trypanosoma cruzi: What do we know so far?

(2020) Ester Rose et al.   DNA REPAIR

Meiotic sex in Chagas disease parasite Trypanosoma cruzi

(2019) Philipp Schwabl et al.   Nature Communications

Genomic assemblies of newly sequenced Trypanosoma cruzi strains reveal new genomic expansion and greater complexity

(2018) Francisco Callejas-Hernández et al.   Scientific Reports

Whole genome sequencing of Trypanosoma cruzi field isolates reveals extensive genomic variability and complex aneuploidy patterns within TcII DTU

(2018) João Luís Reis-Cunha et al.   BMC GENOMICS

Recombination-driven generation of the largest pathogen repository of antigen variants in the protozoan Trypanosoma cruzi

(2016) D. Brent Weatherly et al.   BMC GENOMICS

Transposons passively and actively contribute to evolution of the two-speed genome of a fungal pathogen

(2016) Luigi Faino et al.   GENOME RESEARCH

Indels, structural variation, and recombination drive genomic diversity inPlasmodium falciparum

(2016) Alistair Miles et al.   GENOME RESEARCH

Companion: a web server for annotation and analysis of parasite genomes

(2016) Sascha Steinbiss et al.   NUCLEIC ACIDS RESEARCH

Retrotransposons as regulators of gene expression

(2016) R. A. Elbarbary et al.   SCIENCE

The BENEFIT Trial: Where Do We Go from Here?

(2016) Bernard Pecoul et al.   PLoS Neglected Tropical Diseases

Evidence and importance of genetic exchange among field populations of Trypanosoma cruzi

(2015) Louisa A. Messenger et al.   ACTA TROPICA

The population genetics of Trypanosoma cruzi revisited in the light of the predominant clonal evolution model

(2015) Michel Tibayrenc et al.   ACTA TROPICA

Unbalanced translocations arise from diverse mutational mechanisms including chromothripsis

(2015) Brooke Weckselblatt et al.   GENOME RESEARCH

Global, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2015)   LANCET

Assembling large genomes with single-molecule sequencing and locality-sensitive hashing

(2015) Konstantin Berlin et al.   NATURE BIOTECHNOLOGY

Randomized Trial of Benznidazole for Chronic Chagas’ Cardiomyopathy

(2015) Carlos A. Morillo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chagas’ Disease

(2015) Caryn Bern   NEW ENGLAND JOURNAL OF MEDICINE

Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

(2015) Agnel Sfeir et al.   TRENDS IN BIOCHEMICAL SCIENCES

Detecting non-allelic homologous recombination from high-throughput sequencing data

(2015) Matthew M Parks et al.   GENOME BIOLOGY

Neglected Parasitic Infections in the United States: Chagas Disease

(2014) Susan P. Montgomery et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Mobile DNA elements in the generation of diversity and complexity in the brain

(2014) Jennifer A. Erwin et al.   NATURE REVIEWS NEUROSCIENCE

Generation of Antigenic Diversity in Plasmodium falciparum by Structured Rearrangement of Var Genes During Mitosis

(2014) Antoine Claessens et al.   PLoS Genetics

Genome of the Avirulent Human-Infective Trypanosome—Trypanosoma rangeli

(2014) Patrícia Hermes Stoco et al.   PLoS Neglected Tropical Diseases

Extensive chromosomal reshuffling drives evolution of virulence in an asexual pathogen

(2013) R. de Jonge et al.   GENOME RESEARCH

Genome rearrangements caused by interstitial telomeric sequences in yeast

(2013) A. Y. Aksenova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mosaic Copy Number Variation in Human Neurons

(2013) M. J. McConnell et al.   SCIENCE

Mosaic VSGs and the Scale of Trypanosoma brucei Antigenic Variation

(2013) James P. J. Hall et al.   PLoS Pathogens

Comparative genomic analysis of human infective Trypanosoma cruzi lineages with the bat-restricted subspecies T. cruzi marinkellei

(2012) Oscar Franzén et al.   BMC GENOMICS

Virulence factors of Trypanosoma cruzi: who is who?

(2012) Luis Osorio et al.   MICROBES AND INFECTION

Trypanosoma cruzi I diversity: Towards the need of genetic subdivision?

(2011) Felipe Guhl et al.   ACTA TROPICA

Widespread, focal copy number variations (CNV) and whole chromosome aneuploidies in Trypanosoma cruzi strains revealed by array comparative genomic hybridization

(2011) Todd A Minning et al.   BMC GENOMICS

Trypanosoma cruzi and Chagas' Disease in the United States

(2011) C. Bern et al.   CLINICAL MICROBIOLOGY REVIEWS

The revised Trypanosoma cruzi subspecific nomenclature: Rationale, epidemiological relevance and research applications

(2011) Bianca Zingales et al.   INFECTION GENETICS AND EVOLUTION

The Trypanosoma cruzi genome; conserved core genes and extremely variable surface molecule families

(2011) Björn Andersson   RESEARCH IN MICROBIOLOGY

Shotgun Sequencing Analysis of Trypanosoma cruzi I Sylvio X10/1 and Comparison with T. cruzi VI CL Brener

(2011) Oscar Franzén et al.   PLoS Neglected Tropical Diseases

Chagas disease

(2010) Anis Rassi et al.   LANCET

Chagas Cardiomyopathy Manifestations and Trypanosoma cruzi Genotypes Circulating in Chronic Chagasic Patients

(2010) Juan David Ramírez et al.   PLoS Neglected Tropical Diseases

Chromosome level assembly of the hybrid Trypanosoma cruzi genome

(2009) D Brent Weatherly et al.   BMC GENOMICS

Genome-Scale Multilocus Microsatellite Typing of Trypanosoma cruzi Discrete Typing Unit I Reveals Phylogeographic Structure and Specific Genotypes Linked to Human Infection

(2009) Martin S. Llewellyn et al.   PLoS Pathogens