Article
Multidisciplinary Sciences
Carmina Micelli, Yunfei Dai, Nicole Raustad, Ralph R. Isberg, Christopher G. Dowson, Adrian J. Lloyd, Edward Geisinger, Allister Crow, David I. Roper
Summary: Acinetobacter baumannii is a gram-negative bacterial pathogen that causes challenging nosocomial infections. The study reveals the molecular details of cell wall elongation inhibition upon zinc starvation in A. baumannii. The findings offer a perspective for dual inhibition of zinc-dependent peptidoglycan synthases and metallo-beta-lactamases by metal-chelating agents.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Chemistry, Applied
Monika Topa-Skwarczynska, Patryk Szymaszek, Pawel Fiedor, Anna Chachaj-Brekiesz, Mariusz Galek, Wiktor Kasprzyk, Paulina Koczurkiewicz-Adamczyk, Filip Petko, Elzbieta Pekala, Malgorzata Tyszka-Czochara, Dariusz Bogdal, Tomasz Swiergosz, Roman Popielarz, Joanna Ortyl
Summary: A series of APC derivatives were synthesized and evaluated as fluorescent molecular sensors for chemical and biochemical applications. Some derivatives showed high sensitivity to specific ions and could be applied for ion concentration determination in various media. Moreover, these derivatives were found suitable for imaging living lung cancer cells and were not significantly affected by temperature changes.
Article
Chemistry, Analytical
Hongliang Wang, Dan Song, Yue Zhou, Jiayuan Liu, Anna Zhu, Feng Long
Summary: The significant fluorescence enhancement of CdSe/ZnS quantum dots induced by Hg2+ was observed for the first time using a CdSe/ZnS QD-modified fiber nanoprobe. The fluorescence enhancement mechanism was attributed to Zn-to-Hg cation exchange in the ZnS shell, forming a HgxZn1-xS/CdSe heterojunction. The maximum fluorescence intensity increased over eight times and the characteristic time was linearly dependent on Hg2+ concentration.
Article
Multidisciplinary Sciences
Kelsey L. Anbuhl, Justin D. Yao, Robert A. Hotz, Todd M. Mowery, Dan H. Sanes
Summary: Elevated neural plasticity during development contributes to improvements in perceptual, motor, and cognitive skills. However, malleable neural circuits are vulnerable to environmental influences that may disrupt behavioral maturation. This study found that transient hearing loss during adolescence can cause long-lasting perceptual deficits that originate from degraded auditory cortex processing. Additionally, the study revealed synaptic deficits in the auditory cortex of adolescent animals that are distinct from those typically observed after critical period deprivation.
NATURE COMMUNICATIONS
(2022)
Article
Multidisciplinary Sciences
Helena Farese, Melissa Noack, Pierre Miossec
Summary: The study found that PVNS synoviocytes show resistance to Cd-induced cell death and decreased inflammation, suggesting that Cd could be a potential therapeutic tool in treating PVNS.
SCIENTIFIC REPORTS
(2022)
Article
Cell Biology
Timothy M. Caradonna, Larance Ronsard, Ashraf S. Yousif, Ian W. Windsor, Rachel Hecht, Thalia Bracamonte-Moreno, Anne A. Roffler, Max J. Maron, Daniel P. Maurer, Jared Feldman, Elisa Marchiori, Ralston M. Barnes, Daniel Rohrer, Nils Lonberg, Thomas H. Oguin, Gregory D. Sempowski, Thomas B. Kepler, Masayuki Kuraoka, Daniel Lingwood, Aaron G. Schmidt
Summary: Pathogens can evade host immune responses by accumulating mutations in surface antigens. A study has shown that an epitope-enriched immunogen can enhance B cell responses to conserved epitopes, leading to a specific immune response against influenza viruses.
Article
Materials Science, Multidisciplinary
Qingsong Fan, Yu Lu, Shiyou Xu, Guofeng Xu, Zepeng Cai, Ji Feng, Chaolumen Wu, Tatiana V. Brinzari, Long Pan, Yadong Yin
Summary: This study reports a green, cost-effective, and scalable method for synthesizing colloidal hybrid nanospheres capable of releasing zinc ions in a highly controllable manner. The release rate of zinc ions can be conveniently tuned by changing the shell thickness and cross-linking degree of the silica layer, solvent composition, and surrounding temperature. A novel film capable of recording time-sensitive color information is designed using direct laser writing and further demonstrated its application in steganography by integrating the temperature-sensitive release behavior, color shift associated with the complexation of zinc ions, and photothermal conversion property of gold nanoparticles.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Chemistry, Multidisciplinary
Yongqi Deng, Hongfei Wang, Minghui Fan, Boxiang Zhan, Lu-Jie Zuo, Cheng Chen, Lifeng Yan
Summary: A novel nanomicellar electrolyte using methylurea (Mu) has been developed to guide the homogeneous deposition of Zn2+ / Mn2+ and inhibit water-splitting-derived side reactions. The modified electrolyte also enhances the reversibility of the Mn2+ / MnO2 conversion reaction by regulating interfacial wettability and improving nucleation kinetics. These improvements result in extended cyclic stability, suppressed dendrites growth, exceptional capacity retention, and a high energy density in Zn-Mn batteries.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Haowei Huang, Jiwu Zhao, Bo Weng, Feili Lai, Menglong Zhang, Johan Hofkens, Maarten B. J. Roeffaers, Julian A. Steele, Jinlin Long
Summary: In this study, a new case of materials-gene engineering is demonstrated, which allows for the precise design of photocatalysts with specific properties by regulating CO2 conversion pathways on Au nanoparticles. Twinning Au nanoparticles are found to enhance the activity of the catalyst and achieve near unity CO selectivity, compared to bare TiO2.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Inorganic & Nuclear
Jia-Ning Cui, Hui Zhu, Guang-Hua Cui
Summary: The water-stable luminescent coordination polymer synthesized in this study possesses a stable 3D framework and can be used as a luminescent probe for detecting acetylacetone and Fe3+ ions.
INORGANIC CHEMISTRY COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Mengjie Liu, Hoje Chun, Tsung-Cheng Yang, Sung Jun Hong, Chia-Min Yang, Byungchan Han, Lawrence Yoon Suk Lee
Summary: By modulating the d-orbital energy level, we successfully synthesized N-doped carbon materials with paired metal sites. Compared with other counterparts, the Ru-Co diatomic catalyst exhibited higher oxygen electroreduction activity and better catalytic performance. Moreover, in a gas diffusion Zn-air battery, the Ru-Co diatomic catalyst showed bifunctional activity that outperformed commercial catalysts.
Article
Chemistry, Multidisciplinary
Tim Pasch, Alexander Schroeder, Sabrina Kattelmann, Miriam Eisenstein, Shmuel Pietrokovski, Daniel Kuemmel, Henning D. Mootz
Summary: This article reports a new cysteine-independent split intein that plays an important role in protein splicing. By rational engineering, a higher-yielding split intein mutant was obtained, and a histidine residue critical for splicing was identified. These findings advance the toolbox, as well as the structural and mechanistic understanding of cysteine-less inteins.
Article
Engineering, Environmental
Jianhong Shi, Baoyi Lv, Binghan Wang, Bing Xie
Summary: Microplastic (MP) biofilms in landfill environment are hotspots of antibiotic resistance genes (ARGs), which are influenced by heavy metals and metallic nanoparticles (NPs) known as selective agents of ARGs. This study comparatively analyzed the effects of zinc oxide (ZnO) NPs and zinc ion (Zn2+) pressures on ARG abundances in MP biofilms and corresponding leachate. The presence of ZnO NPs and Zn2+ enhanced the enrichment of ARGs in MP biofilms, with ZnO NPs having a more pronounced effect. ZnO NPs and Zn2+ mainly decreased the abundances of ARGs in leachate.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Chemistry, Applied
Barun Mondal, Shankha Banerjee, Santu Kumar Samanta, Sanjib Senapati, Tridib Tripathy
Summary: A highly sensitive and selective electrochemical sensor for detecting Zn2+ ions in water with detection limit of 0.53 nM was developed using Tricholoma mushroom polysaccharide-based silver composite nanoparticles. The sensor showed excellent performance in detecting Zn2+ ions without interference from other metal ions, and demonstrated stability and reproducibility properties. The practical application of the sensor in river water sample testing also yielded excellent results.
APPLIED ORGANOMETALLIC CHEMISTRY
(2021)
Article
Biotechnology & Applied Microbiology
Youdong Hu, Hualan Zhou, Tingting Liu, Minhui Yang, Qiuyang Zhang, Changjiang Pan, Jiafeng Lin
Summary: Zinc ions have broad physiological functions and their continuous and controllable release from biomaterials can enhance biocompatibility and antibacterial activity. This study developed a biomimetic dopamine-zinc ion coating to improve the biocompatibility of titanium, which exhibited excellent hydrophilicity and demonstrated enhanced hemocompatibility, endothelial cell adhesion, and antibacterial activity.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Reproductive Biology
Jie Sheng, Yange Yang, Wei Liu, Honglei Ji, Anmin Lei, Suzhu Qing
Article
Agriculture, Dairy & Animal Science
Y. Yin, J. Sheng, R. Hu, Y. Yang, S. Qing
REPRODUCTION IN DOMESTIC ANIMALS
(2014)
Article
Biochemistry & Molecular Biology
Jie Sheng, Nick K. Olrichs, Willie J. Geerts, Xueyi Li, Ashfaq Ur Rehman, Barend M. Gadella, Dora V. Kaloyanova, J. Bernd Helms
BIOSCIENCE REPORTS
(2019)
Article
Multidisciplinary Sciences
Jie Sheng, Nick K. Olrichs, Willie J. Geerts, Dora V. Kaloyanova, J. Bernd Helms
SCIENTIFIC REPORTS
(2019)
Review
Biochemistry & Molecular Biology
Jie Sheng, Nick K. Olrichs, Bart M. Gadella, Dora Kaloyanova, J. Bernd Helms
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)