Review
Biochemical Research Methods
Soumyabrata Banik, Sindhoora Kaniyala Melanthota, Arbaaz, Joel Markus Vaz, Vishak Madhwaraj Kadambalithaya, Iftak Hussain, Sibasish Dutta, Nirmal Mazumder
Summary: Smartphone-based imaging devices have a wide range of biomedical applications, including histopathological examination, detection of bacteria and viruses, food technology, and routine diagnosis. The optical arrangement of these devices can be adjusted based on specific requirements, enhancing their versatility and applicability in various settings. These devices are also enhanced with deep learning methods to improve efficiency.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Materials Science, Multidisciplinary
Jiang Ouyang, Zhongyang Zhang, Bo Deng, Jinggong Liu, Liqiang Wang, Haijun Liu, Seyoung Koo, Shuying Chen, Yongjiang Li, Alexey V. Yaremenko, Xiangang Huang, Wei Chen, Yuhan Lee, Wei Tao
Summary: Oral administration is widely used for drug delivery due to its non-invasiveness and simplicity. However, conventional delivery methods may result in low drug bioavailability, particularly for biologics. To overcome this, various carriers have been developed to protect and enhance drug absorption in the gastrointestinal tract. This review summarizes different drug molecules used for oral administration, discusses physiological barriers and targeting regions in the GI tract, reviews recent oral drug delivery platforms, and presents future perspectives and challenges.
Review
Materials Science, Multidisciplinary
Jiwei Li, Yujie Feng, Weichao Chen, Shaohua Zhang, Jianwei Ma, Shaojuan Chen, Shangpeng Liu, Chengbo Cao, Yuankai Zhang
Summary: This review focuses on the structural design and antibacterial mechanisms of electroactive materials, including electrochemical materials, conductive materials, piezoelectric materials, and micro-batteries/galvanic couples. It also describes the biomedical applications of electroactive antibacterial materials in various areas such as bone tissue engineering, wound healing, medical catheters, oral healthcare, and wearable devices. The future challenges and perspectives associated with electroactive antibacterial materials are discussed. In summary, electroactive materials offer a promising platform for fighting bacterial infections and play a crucial role in the field of biomedicine.
PROGRESS IN MATERIALS SCIENCE
(2023)
Review
Biochemistry & Molecular Biology
Tejal V. Patil, Dinesh K. Patel, Sayan Deb Dutta, Keya Ganguly, Ki-Taek Lim
Summary: Graphene, a two-dimensional sp(2) hybridized carbon material, has garnered significant attention for its excellent properties in stimuli-responsive applications. Stimuli-responsive materials in the biomedical field are of particular interest for their potential to change behavior under different conditions, with graphene-based materials showing superior biocompatibility and various applications.
Review
Chemistry, Applied
Wenbin Hu, Sanying Wang, Chenyi Jiang, Minbin Zheng, Zhi Bai, Devyani Srivastava, Abhinav Kumar, Jianqiang Liu
Summary: Sonodynamic therapy (SDT) is a new treatment method that combines low-intensity ultrasound with sonosensitizers. Metal-organic frameworks (MOFs) have shown potential as efficient carriers for sono-sensitizers in SDT. This review discusses the use of different types of MOFs as carriers for sono-sensitizers and the latest research progress in enhancing SDT.
Article
Computer Science, Hardware & Architecture
Filippo Cugini, Davide Scano, Alessio Giorgetti, Andrea Sgambelluri, Lorenzo De Marinis, Piero Castoldi, Francesco Paolucci
Summary: This paper presents the potentials and challenges of programmable packet-optical nodes in the context of optical metro networks, and introduces two innovative applications of P4-based data plane programmability.
JOURNAL OF OPTICAL COMMUNICATIONS AND NETWORKING
(2023)
Review
Chemistry, Analytical
Baptiste Moeglen Paget, Keertana Vinod Ram, Shuyan Zhang, Jayakumar Perumal, Sylvain Vedraine, Georges Humbert, Malini Olivo, U. S. Dinish
Summary: Photonic crystal fibers (PCFs) have unique light-guiding properties and have been widely studied for biomedical applications. PCF-based fluorescence sensors offer highly sensitive detection of biomolecules at low sample volumes. This review discusses recent advancements in fluorescence detection using different PCF configurations and compares them with conventional fluorescence methods. Prospective applications of PCF-based fluorescence sensing and their potential use as optofluidic biopsy needles for clinically relevant biomarker detection are also discussed.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Review
Optics
Vinoth Balasubramani, Arkadiusz Kus, Han-Yen Tu, Chau-Jern Cheng, Maria Baczewska, Wojciech Krauze, Malgorzata Kujawinska
Summary: Holographic tomography is an advanced label-free optical microscopic imaging method used for biological studies, allowing for the recording and reconstruction of a sample's refractive index distribution. The refractive index values are crucial parameters for bio-examination, correlating with metabolic activities and spatial distribution of biophysical parameters of cells and biological objects.
Review
Chemistry, Applied
Hamid Hamedi, Sara Moradi, Samuel M. Hudson, Alan E. Tonelli, Martin W. King
Summary: This paper discusses the importance and potential of chitosan in biomedical engineering applications. Different types of chitosan-based bioadhesives and their external stimulus responsive structures are discussed. The potential applications of chitosan bioadhesives in drug delivery systems, surgery, wound dressing, and hemostatic are also presented.
CARBOHYDRATE POLYMERS
(2022)
Article
Engineering, Environmental
Zhixiang Lu, Shuang Bai, Yesi Shi, Dazhuang Xu, Chengchao Chu, Gang Liu
Summary: This review summarizes the unique properties and common topological types of nanocages with great potential in biomedical applications. It focuses on reviewing recent progress and emerging multi-functional bioengineering for effective drug delivery, imaging, diagnosis, and treatment. The remaining challenges and suggestions for the rational design of next-generation nanocages are also discussed.
CHEMICAL ENGINEERING JOURNAL
(2021)
Review
Chemistry, Analytical
Lingyu Shen, Chuanxin Teng, Zhuo Wang, Hongyi Bai, Santosh Kumar, Rui Min
Summary: This article presents an overview of integrated sensors and transmitters in multimaterial optical fibers, discussing their fabrication and postprocessing techniques. It also explores the applications of semiconductor optical fibers in biomedical fields.
Review
Materials Science, Multidisciplinary
Shichao Ding, Nan Zhang, Zhaoyuan Lyu, Wenlei Zhu, Yu-Chung Chang, Xiaoling Hu, Dan Du, Yuehe Lin
Summary: Protein-based nanomaterials and nanosystems (PNNS) have captured significant scientific interest in recent years due to their potential in bio-applications, with a focus on designing multi-functional PNNS based on different protein characteristics. The latest developments in unique synthesis strategies and detailed classifications of PNNS have been reviewed, highlighting the functions of proteins in biomedical applications such as targeting, carriers, enzymes, and fluorescent indicators. Challenges and future prospects in PNNS research have also been discussed.
Review
Chemistry, Multidisciplinary
Bo Chen, Hongyan Sun, Jiaying Zhang, Junjie Xu, Zeyu Song, Guangdong Zhan, Xue Bai, Lin Feng
Summary: Micro/nano-robots are powerful tools for biomedical applications and can be used for disease diagnosis, tumor imaging, drug delivery, and targeted therapy. Cell-based micro-robots have unique properties due to their different cell sources, and when combined with various actuation methods, particularly externally propelled methods, they have enormous potential in biomedicine. This review provides an overview of recent progress and applications of cell-based micro/nano-robots, including different actuation methods and cell templates, as well as the combination of these robots with precise control using external fields. Potential challenges, future prospects, and clinical translations are also discussed.
Review
Chemistry, Multidisciplinary
Cezar Tipa, Maria T. Cidade, Joao P. Borges, Luis C. Costa, Jorge C. Silva, Paula I. P. Soares
Summary: In recent decades, there has been a significant interest in the development of new materials, particularly three-dimensional scaffolds, that can meet the diverse needs of the expanding biomedical field. Hydrogels, due to their biocompatibility and ability to mimic the extracellular matrix, have been extensively studied in biomedical applications. However, their poor mechanical integrity and limited cell interaction have limited their broad applicability. To overcome these limitations, researchers have focused on incorporating nanoparticles into polymeric gels to form nanocomposites with tailored functionality and improved properties. This review specifically emphasizes the unique contributions of clay nanoparticles in clay-based nanocomposite hydrogels and their biomedical applications.
Article
Optics
Emil Pitula, Marcin Koba, Mateusz Smietana
Summary: This work discusses the application of over 60 various smartphones as low-cost spectrometers and analyzes the influence of hardware and software components and settings on the obtained spectrum. Optical fiber sensors based on lossy-mode resonance effect were tested using commercial and selected smartphone-based spectrometers, with limitations of smartphone-based solution for refractive index sensing discussed.
OPTICS AND LASER TECHNOLOGY
(2021)
Article
Chemistry, Analytical
Iftak Hussain, Kamal Uddin Ahamad, Pabitra Nath
ANALYTICAL CHEMISTRY
(2017)
Article
Chemistry, Analytical
Iftak Hussain, Munmun Das, Kamal Uddin Ahamad, Pabitra Nath
SENSORS AND ACTUATORS B-CHEMICAL
(2017)
Article
Engineering, Electrical & Electronic
Iftak Hussain, Anup Jyoti Bora, Dhrubanka Sarma, Kamal Uddin Ahamad, Pabitra Nath
IEEE SENSORS JOURNAL
(2018)
Article
Instruments & Instrumentation
I. Hussain, P. Nath
REVIEW OF SCIENTIFIC INSTRUMENTS
(2018)
Review
Biochemical Research Methods
Soumyabrata Banik, Sindhoora Kaniyala Melanthota, Arbaaz, Joel Markus Vaz, Vishak Madhwaraj Kadambalithaya, Iftak Hussain, Sibasish Dutta, Nirmal Mazumder
Summary: Smartphone-based imaging devices have a wide range of biomedical applications, including histopathological examination, detection of bacteria and viruses, food technology, and routine diagnosis. The optical arrangement of these devices can be adjusted based on specific requirements, enhancing their versatility and applicability in various settings. These devices are also enhanced with deep learning methods to improve efficiency.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Multidisciplinary Sciences
Emily Kight, Iftak Hussain, Audrey K. Bowden
Summary: Dipstick urinalysis provides quick and affordable estimations of multiple physiological conditions, but requires good technique and training. Automating key steps can eliminate error sources, allowing for self-testing at home. Customizable device and mobile app provide simple and efficient analysis.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
(2021)
Article
Multidisciplinary Sciences
Emily C. Kight, Iftak Hussain, Audrey K. Bowden, Frederick R. Haselton
Summary: A paper-based device has been developed to quantitatively measure the HE4/CRE ratio in the urine of ovarian cancer patients. The tool performed well when measured by either a cell phone or scanner, showing potential for future application.
SCIENTIFIC REPORTS
(2021)
Article
Biochemical Research Methods
Joseph D. Malone, Iftak Hussain, Audrey K. Bowden
Summary: Smartphone devices have undergone significant technical advancements in computational power and optical imaging capabilities, making them highly valuable tools in scientific imaging applications. The compact size and widespread use of smartphones have led to the development of smartphone-integrated imaging systems for various applications. The study demonstrates smartOCT, a smartphone-integrated OCT system that utilizes the built-in components of a smartphone for OCT data detection, processing, and display. The system employs a broadband visible-light source and line-field OCT design, enabling quick 2D cross-sectional imaging. Methods for processing smartphone data in a RAW format are described, improving the quality of OCT images for scientific applications. The results highlight the potential of smartphone-integrated OCT systems in low-resource environments.
BIOMEDICAL OPTICS EXPRESS
(2023)
Article
Chemistry, Analytical
Iftak Hussain, Andrea Locke, Emily Kight, Joseph D. Malone, Frederick Haselton, Audrey K. Bowden
Summary: Primary healthcare centers serve as the first point of contact for people in low-resource settings, and laboratory services are crucial for early disease diagnosis. Smartphone-based spectroscopic systems have been developed to improve accessibility by bringing lab-confined healthcare applications into point-of-care environments. This study introduces a smartphone-based spectroscopic system using line-beam illumination to achieve high-throughput sensing within a 3D-printed microfluidic device. The system allows simultaneous detection in 15 channels and can be operated with limited manpower and infrastructure, enabling rapid and efficient testing of multiple samples.
Proceedings Paper
Remote Sensing
T. Das, D. Hatiboruah, N. Chamuah, I Hussain, U. Bora, P. Nath
OPTICAL SENSING AND DETECTION V
(2018)
Article
Optics
Iftak Hussain, Pabitra Nath
Article
Physics, Multidisciplinary
P. Nath, I. Hussain, S. Dutta, A. Choudhury
INDIAN JOURNAL OF PHYSICS
(2014)
Article
Multidisciplinary Sciences
Pabitra Nath, Iftak Hussain, Rajib Biswas
Article
Chemistry, Multidisciplinary
I. Hussain, K. Ahamad, P. Nath
