Amyloid-β oligomer targeted theranostic probes for in vivo NIR imaging and inhibition of self-aggregation and amyloid-β induced ROS generation

A hemicyanine derivative for near-infrared imaging of β-amyloid plaques in Alzheimer's disease

(2019) Hua-Li Yang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Development of novel theranostic agents for in vivo amyloid imaging and protective effects on human neuroblastoma cells

(2019) Yongliang Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Toward a Rational Design to Regulate β-Amyloid Fibrillation for Alzheimer’s Disease Treatment

(2018) Xu Han et al.   ACS Chemical Neuroscience

Fluoro-substituted cyanine for reliable in vivo labelling of amyloid-β oligomers and neuroprotection against amyloid-β induced toxicity

(2017) Yinhui Li et al.   Chemical Science

Near-infrared fluorophores for biomedical imaging

(2017) Guosong Hong et al.   Nature Biomedical Engineering

Alzheimer's Disease and the Amyloid-β Peptide

(2017) M. Paul Murphy et al.   JOURNAL OF ALZHEIMERS DISEASE

A theranostic agent for in vivo near-infrared imaging of β-amyloid species and inhibition of β-amyloid aggregation

(2016) Yinhui Li et al.   BIOMATERIALS

A spiropyran-based fluorescent probe for the specific detection of β-amyloid peptide oligomers in Alzheimer's disease

(2016) Guanglei Lv et al.   CHEMICAL COMMUNICATIONS

Structure of aggregates revealed

(2016) Robert Tycko   NATURE

Imaging of β-amyloid plaques by near infrared fluorescent tracers: a new frontier for chemical neuroscience

(2015) Matteo Staderini et al.   CHEMICAL SOCIETY REVIEWS

Synthesis and structure-activity relationship study of benzofuran-based chalconoids bearing benzylpyridinium moiety as potent acetylcholinesterase inhibitors

(2015) Manizheh Mostofi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Molecular Design for Dual Modulation Effect of Amyloid Protein Aggregation

(2015) Lijuan Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemical Fluorescent Probe for Detection of Aβ Oligomers

(2015) Chai Lean Teoh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PET/SPECT imaging agents for neurodegenerative diseases

(2014) Lin Zhu et al.   CHEMICAL SOCIETY REVIEWS

Current status of PET-imaging probes of β-amyloid plaques

(2013) JaeHyung Koo et al.   ARCHIVES OF PHARMACAL RESEARCH

99mTc-labeled dibenzylideneacetone derivatives as potential SPECT probes for in vivo imaging of β-amyloid plaque

(2013) Yanping Yang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Far-red to near infrared analyte-responsive fluorescent probes based on organic fluorophore platforms for fluorescence imaging

(2012) Lin Yuan et al.   CHEMICAL SOCIETY REVIEWS

Technetium-99m Labeled Pyridyl Benzofuran Derivatives as Single Photon Emission Computed Tomography Imaging Probes for β-Amyloid Plaques in Alzheimer’s Brains

(2012) Yan Cheng et al.   JOURNAL OF MEDICINAL CHEMISTRY

In Situ Measurements of the Formation and Morphology of Intracellular β-Amyloid Fibrils by Super-Resolution Fluorescence Imaging

(2011) Gabriele S. Kaminski Schierle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Detection of Aβ Plaques by a Novel Specific MRI Probe Precursor CR-BSA-(Gd-DTPA)n in APP/PS1 Transgenic Mice

(2010) Shuping Li et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Design, Synthesis, and Testing of Difluoroboron-Derivatized Curcumins as Near-Infrared Probes for in Vivo Detection of Amyloid-β Deposits

(2009) Chongzhao Ran et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PET radiotracers: crossing the blood–brain barrier and surviving metabolism

(2009) Victor W. Pike   TRENDS IN PHARMACOLOGICAL SCIENCES

Synthesis, radiolabeling and baboon SPECT imaging of 2β-carbomethoxy-3β-(3′-[123I]iodophenyl)tropane ([123I]YP256) as a serotonin transporter radiotracer

(2007) Frederic Bois et al.   NUCLEAR MEDICINE AND BIOLOGY