Extracellular vesicles deposit PCNA to rejuvenate aged bone marrow–derived mesenchymal stem cells and slow age-related degeneration
出版年份 2021 全文链接
标题
Extracellular vesicles deposit PCNA to rejuvenate aged bone marrow–derived mesenchymal stem cells and slow age-related degeneration
作者
关键词
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出版物
Science Translational Medicine
Volume 13, Issue 578, Pages eaaz8697
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2021-01-28
DOI
10.1126/scitranslmed.aaz8697
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Lentivirus expressing shRNAs inhibit the replication of contagious ecthyma virus by targeting DNA polymerase gene
- (2020) Leila Asadi Samani et al. BMC BIOTECHNOLOGY
- FOXO3-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration
- (2019) Pengze Yan et al. Cell Stem Cell
- Maintenance of Nucleolar Homeostasis by CBX4 Alleviates Senescence and Osteoarthritis
- (2019) Xiaoqing Ren et al. Cell Reports
- Highly Purified Human Extracellular Vesicles Produced by Stem Cells Alleviate Aging Cellular Phenotypes of Senescent Human Cells
- (2019) Senquan Liu et al. STEM CELLS
- Reassessment of Exosome Composition
- (2019) Dennis K. Jeppesen et al. CELL
- Nicotinamide mononucleotide promotes osteogenesis and reduces adipogenesis by regulating mesenchymal stromal cells via the SIRT1 pathway in aged bone marrow
- (2019) Jie Song et al. Cell Death & Disease
- Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice
- (2019) Mitsukuni Yoshida et al. Cell Metabolism
- Human umbilical cord mesenchymal stem cell-derived extracellular vesicles: A novel therapeutic paradigm
- (2019) Hossein Abbaszadeh et al. JOURNAL OF CELLULAR PHYSIOLOGY
- From discoveries in ageing research to therapeutics for healthy ageing
- (2019) Judith Campisi et al. NATURE
- Lactobacillus acidophilus DDS-1 Modulates Intestinal-Specific Microbiota, Short-Chain Fatty Acid and Immunological Profiles in Aging Mice
- (2019) Ravichandra Vemuri et al. Nutrients
- Intranasal Delivery of Mesenchymal Stem Cell Derived Exosomes Loaded with Phosphatase and Tensin Homolog siRNA Repairs Complete Spinal Cord Injury
- (2019) Shaowei Guo et al. ACS Nano
- Therapeutic effects of human umbilical cord mesenchymal stem cell-derived microvesicles on premature ovarian insufficiency in mice
- (2019) Ziling Yang et al. Stem Cell Research & Therapy
- Extracellular vesicles circulating in young organisms promote healthy longevity
- (2019) Francesco Prattichizzo et al. Journal of Extracellular Vesicles
- Bone marrow mesenchymal stem cells: Aging and tissue engineering applications to enhance bone healing
- (2018) Hang Lin et al. BIOMATERIALS
- Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities
- (2018) Jacques Galipeau et al. Cell Stem Cell
- Anti-Aging Effect of Chitosan Oligosaccharide on d-Galactose-Induced Subacute Aging in Mice
- (2018) Song-Zhi Kong et al. Marine Drugs
- The Fas/Fap-1/Cav-1 complex regulates IL-1RA secretion in mesenchymal stem cells to accelerate wound healing
- (2018) Xiaoxing Kou et al. Science Translational Medicine
- Hypoxia induces senescence of bone marrow mesenchymal stem cells via altered gut microbiota
- (2018) Junyue Xing et al. Nature Communications
- Thy-1 (CD90) promotes bone formation and protects against obesity
- (2018) Ann-Kristin Picke et al. Science Translational Medicine
- Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication
- (2018) Mathilde Mathieu et al. NATURE CELL BIOLOGY
- EVmiRNA: a database of miRNA profiling in extracellular vesicles
- (2018) Teng Liu et al. NUCLEIC ACIDS RESEARCH
- Safety, Tolerability, and Feasibility of Young Plasma Infusion in the Plasma for Alzheimer Symptom Amelioration Study
- (2018) Sharon J. Sha et al. JAMA Neurology
- Cardiac and systemic rejuvenation after cardiosphere-derived cell therapy in senescent rats
- (2017) Lilian Grigorian-Shamagian et al. EUROPEAN HEART JOURNAL
- Macrophage-derived apoptotic bodies promote the proliferation of the recipient cells via shuttling microRNA-221/222
- (2017) Ziwen Zhu et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Functional Delivery of Lipid-Conjugated siRNA by Extracellular Vesicles
- (2017) Aisling J. O’Loughlin et al. MOLECULAR THERAPY
- Human umbilical cord plasma proteins revitalize hippocampal function in aged mice
- (2017) Joseph M. Castellano et al. NATURE
- Hypothalamic stem cells control ageing speed partly through exosomal miRNAs
- (2017) Yalin Zhang et al. NATURE
- Targeting cellular senescence prevents age-related bone loss in mice
- (2017) Joshua N Farr et al. NATURE MEDICINE
- Intercellular Transfer of Microvesicles from Young Mesenchymal Stromal Cells Rejuvenates Aged Murine Hematopoietic Stem Cells
- (2017) Rohan Kulkarni et al. STEM CELLS
- Extracellular Vesicle-functionalized Decalcified Bone Matrix Scaffolds with Enhanced Pro-angiogenic and Pro-bone Regeneration Activities
- (2017) Hui Xie et al. Scientific Reports
- Microvesicles as Potential Biomarkers for the Identification of Senescence in Human Mesenchymal Stem Cells
- (2017) Qian Lei et al. Theranostics
- Exosome-Transmitted lncARSR Promotes Sunitinib Resistance in Renal Cancer by Acting as a Competing Endogenous RNA
- (2016) Le Qu et al. CANCER CELL
- miR-146b-5p within BCR-ABL1-Positive Microvesicles Promotes Leukemic Transformation of Hematopoietic Cells
- (2016) H.-M. Zhang et al. CANCER RESEARCH
- In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming
- (2016) Alejandro Ocampo et al. CELL
- Repression of the Antioxidant NRF2 Pathway in Premature Aging
- (2016) Nard Kubben et al. CELL
- Clinical Trials with Mesenchymal Stem Cells: An Update
- (2016) Tiziana Squillaro et al. CELL TRANSPLANTATION
- Secretome of Human Fetal Mesenchymal Stem Cell Ameliorates Replicative Senescence
- (2016) Bin Wang et al. STEM CELLS AND DEVELOPMENT
- Role of VEGF-A in angiogenesis promoted by umbilical cord-derived mesenchymal stromal/stem cells: in vitro study
- (2016) Irina Arutyunyan et al. Stem Cell Research & Therapy
- Melatonin Treatment Improves Mesenchymal Stem Cells Therapy by Preserving Stemness during Long-term In Vitro Expansion
- (2016) Yi Shuai et al. Theranostics
- Development of an angiogenesis-promoting microvesicle-alginate-polycaprolactone composite graft for bone tissue engineering applications
- (2016) Hui Xie et al. PeerJ
- Mesenchymal stem cell aging: Mechanisms and influences on skeletal and non-skeletal tissues
- (2015) Huijuan Liu et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Exosomes/microvesicles from induced pluripotent stem cells deliver cardioprotective miRNAs and prevent cardiomyocyte apoptosis in the ischemic myocardium
- (2015) Yingjie Wang et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Beclin 1 regulates neuronal transforming growth factor-β signaling by mediating recycling of the type I receptor ALK5
- (2015) Caitlin E. O’Brien et al. Molecular Neurodegeneration
- Influence of erythropoietin on microvesicles derived from mesenchymal stem cells protecting renal function of chronic kidney disease
- (2015) Yan Wang et al. Stem Cell Research & Therapy
- Accelerated Regeneration of Skin Injury by Co-transplantation of Mesenchymal Stem Cells from Wharton’s Jelly of the Human Umbilical Cord Mixed with Microparticles
- (2014) Shengjun Shi et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA
- (2014) Marco Demaria et al. DEVELOPMENTAL CELL
- Hypomorphic PCNA mutation underlies a human DNA repair disorder
- (2014) Emma L. Baple et al. JOURNAL OF CLINICAL INVESTIGATION
- BCR-ABL1–positive microvesicles transform normal hematopoietic transplants through genomic instability: implications for donor cell leukemia
- (2014) X Zhu et al. LEUKEMIA
- Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice
- (2014) Saul A Villeda et al. NATURE MEDICINE
- Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors
- (2014) L. Katsimpardi et al. SCIENCE
- Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle
- (2014) M. Sinha et al. SCIENCE
- A Systematic Review of Preclinical Studies on the Therapeutic Potential of Mesenchymal Stromal Cell-Derived Microvesicles
- (2014) Celine Akyurekli et al. Stem Cell Reviews and Reports
- SIRT1 Directly Regulates SOX2 to Maintain Self-Renewal and Multipotency in Bone Marrow-Derived Mesenchymal Stem Cells
- (2014) Dong Suk Yoon et al. STEM CELLS
- PCNA: a silent housekeeper or a potential therapeutic target?
- (2014) Shao-Chun Wang TRENDS IN PHARMACOLOGICAL SCIENCES
- Aging disrupts cell subpopulation dynamics and diminishes the function of mesenchymal stem cells
- (2014) Dominik Duscher et al. Scientific Reports
- Serum deprivation elevates the levels of microvesicles with different size distributions and selectively enriched proteins in human myeloma cells in vitro
- (2013) Li Sun et al. ACTA PHARMACOLOGICA SINICA
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy
- (2013) Francesco S. Loffredo et al. CELL
- Microvesicles Derived from Human Umbilical Cord Wharton’s Jelly Mesenchymal Stem Cells Attenuate Bladder Tumor Cell Growth In Vitro and In Vivo
- (2013) Shuai Wu et al. PLoS One
- RTEL1 Is a Replisome-Associated Helicase That Promotes Telomere and Genome-Wide Replication
- (2013) J.-B. Vannier et al. SCIENCE
- Human Mesenchymal Stem Cell Microvesicles for Treatment ofEscherichia coliEndotoxin-Induced Acute Lung Injury in Mice
- (2013) Ying-gang Zhu et al. STEM CELLS
- Aging, Cellular Senescence, and Cancer
- (2012) Judith Campisi Annual Review of Physiology
- Rejuvenation of Regeneration in the Aging Central Nervous System
- (2012) Julia M. Ruckh et al. Cell Stem Cell
- Role of Exosomes/Microvesicles in the Nervous System and Use in Emerging Therapies
- (2012) Charles Pin-Kuang Lai et al. Frontiers in Physiology
- Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury
- (2011) S. Gatti et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Lipophilic Dye Staining ofCryptococcus neoformansExtracellular Vesicles and Capsule
- (2009) André Moraes Nicola et al. EUKARYOTIC CELL
- Age-related intrinsic changes in human bone-marrow-derived mesenchymal stem cells and their differentiation to osteoblasts
- (2008) Shuanhu Zhou et al. AGING CELL
- The aging kidney
- (2008) Xin J. Zhou et al. KIDNEY INTERNATIONAL
- Replicative Senescence of Mesenchymal Stem Cells: A Continuous and Organized Process
- (2008) Wolfgang Wagner et al. PLoS One
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