Dual role of endothelial Myct1 in tumor angiogenesis and tumor immunity

Identification of gene signature for treatment response to guide precision oncology in clear-cell renal cell carcinoma

(2020) Ninadh M. D’Costa et al.   Scientific Reports

Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer

(2019) Ivy X. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Normalizing Function of Tumor Vessels: Progress, Opportunities, and Challenges

(2019) John D. Martin et al.   Annual Review of Physiology

GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis

(2019) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy

(2019) Vikash P. Chauhan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Vascular regulation of antitumor immunity

(2019) Lance L. Munn et al.   SCIENCE

Regulatory T cells: a potential target in cancer immunotherapy

(2018) Kohei Shitara et al.   Annals of the New York Academy of Sciences

Single-Cell Transcriptome Analyses Reveal Endothelial Cell Heterogeneity in Tumors and Changes following Antiangiogenic Treatment

(2018) Qi Zhao et al.   CANCER RESEARCH

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges

(2018) Dai Fukumura et al.   Nature Reviews Clinical Oncology

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

(2018) et al.   NATURE

ETV2/ER71 regulates hematopoietic regeneration by promoting hematopoietic stem cell proliferation

(2017) Can-Xin Xu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming

(2017) Lin Tian et al.   NATURE

SCENIC: single-cell regulatory network inference and clustering

(2017) Sara Aibar et al.   NATURE METHODS

Dual angiopoietin-2 and VEGFA inhibition elicits antitumor immunity that is enhanced by PD-1 checkpoint blockade

(2017) Martina Schmittnaegel et al.   Science Translational Medicine

Combined antiangiogenic and anti–PD-L1 therapy stimulates tumor immunity through HEV formation

(2017) Elizabeth Allen et al.   Science Translational Medicine

Temporally Distinct PD-L1 Expression by Tumor and Host Cells Contributes to Immune Escape

(2017) Takuro Noguchi et al.   Cancer Immunology Research

Fibulin-4 is essential for maintaining arterial wall integrity in conduit but not muscular arteries

(2017) Carmen M. Halabi et al.   Science Advances

Antagonizing Integrin  3 Increases Immunosuppression in Cancer

(2016) X. Su et al.   CANCER RESEARCH

The Complexity of Translating Anti-angiogenesis Therapy from Basic Science to the Clinic

(2016) Weilan Ye   DEVELOPMENTAL CELL

Bioinformatic analysis of c-Myc target from laryngeal cancer cell gene of laryngeal cancer

(2016) Wei-Dong Zhang et al.   Journal of Cancer Research and Therapeutics

Ten years of anti-vascular endothelial growth factor therapy

(2016) Napoleone Ferrara et al.   NATURE REVIEWS DRUG DISCOVERY

Injury-Mediated Vascular Regeneration Requires Endothelial ER71/ETV2Significance

(2015) Changwon Park et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

M2 Macrophage Polarization Mediates Anti-inflammatory Effects of Endothelial Nitric Oxide Signaling

(2015) Woo Je Lee et al.   DIABETES

Induction of hematopoietic and endothelial cell program orchestrated by ETS transcription factor ER71/ETV2

(2015) F. Liu et al.   EMBO REPORTS

ZO-1 controls endothelial adherens junctions, cell–cell tension, angiogenesis, and barrier formation

(2015) Olga Tornavaca et al.   JOURNAL OF CELL BIOLOGY

Transmembrane domain is crucial to the subcellular localization and function of Myc target 1

(2015) Shuai Wu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

VEGF-A modulates expression of inhibitory checkpoints on CD8+T cells in tumors

(2015) Thibault Voron et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Myeloid cell-derived inducible nitric oxide synthase suppresses M1 macrophage polarization

(2015) Geming Lu et al.   Nature Communications

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Nitric Oxide Prevents Aortic Neointimal Hyperplasia by Controlling Macrophage Polarization

(2014) Begoña Lavin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors

(2014) Gregory T Motz et al.   NATURE MEDICINE

Melittin derived peptides for nanoparticle based siRNA transfection

(2013) Kirk K. Hou et al.   BIOMATERIALS

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

A Core Human Primary Tumor Angiogenesis Signature Identifies the Endothelial Orphan Receptor ELTD1 as a Key Regulator of Angiogenesis

(2013) Massimo Masiero et al.   CANCER CELL

Anti-VEGF- and anti-VEGF receptor-induced vascular alteration in mouse healthy tissues

(2013) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VEGFA-VEGFR Pathway Blockade Inhibits Tumor-Induced Regulatory T-cell Proliferation in Colorectal Cancer

(2012) M. Terme et al.   CANCER RESEARCH

Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy

(2012) Y. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developmental and Pathological Angiogenesis

(2011) Alicia S. Chung et al.   Annual Review of Cell and Developmental Biology

Human Solid Tumors Contain High Endothelial Venules: Association with T- and B-Lymphocyte Infiltration and Favorable Prognosis in Breast Cancer

(2011) L. Martinet et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The 'invisible hand': regulation of RHO GTPases by RHOGDIs

(2011) Rafael Garcia-Mata et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SEURAT: Visual analytics for the integrated analysis of microarray data

(2010) Alexander Gribov et al.   BMC Medical Genomics

Dynamics of endothelial cell behavior in sprouting angiogenesis

(2010) Hanna M Eilken et al.   CURRENT OPINION IN CELL BIOLOGY

ER71 Acts Downstream of BMP, Notch, and Wnt Signaling in Blood and Vessel Progenitor Specification

(2008) Dongjun Lee et al.   Cell Stem Cell

The Immunological Genome Project: networks of gene expression in immune cells

(2008) Tracy S P Heng et al.   NATURE IMMUNOLOGY