Article
Environmental Sciences
Erika Noren, Christian Lindh, Anders Glynn, Lars Rylander, Daniela Pineda, Christel Nielsen
Summary: The study assessed temporal trends of PFAAs concentrations in serum of Swedish adolescents and found that some compounds decreased annually, while others increased up to 2009 and decreased thereafter. Sensitivity analysis showed consistent trends. Furthermore, the results indicated that PFAAs remain stable in serum samples after long-term storage.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Chemistry, Physical
Marcin Czapla, Piotr Skurski
Summary: The conversion of perfluorinated carboxylic acids and perfluorinated sulfonic acids into perfluoroalkenes in aqueous solutions is studied using electronic structure methods. It is shown that aluminum trifluoride can enable these conversions at room temperature within a short time. The mechanism involves the extraction of F- from either the carboxylic or sulfonic acid anions by AlF3, resulting in the formation of a stable AlF4- anion and perfluoroalkene compounds accompanied by CO2 or SO3 loss.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Article
Engineering, Environmental
Ki Yong Kim, Mlamuli Ndabambi, Sol Choi, Jeong-Eun Oh
Summary: The study determined the concentrations of 28 novel and legacy PFASs in wastewater from 77 industrial plants in Korea's largest industrial complex. Only 19 and nine target PFASs were detected in untreated industrial wastewater and river water, respectively. Efforts to reduce the use of Perfluorooctane sulfonate (PFOS) have resulted in its replacement by PFASs with fewer than seven carbon atoms in both industrial wastewater and river water.
Article
Environmental Sciences
Krystyna Makowska, Julia Martin, Andrzej Rychlik, Irene Aparicio, Juan Luis Santos, Esteban Alonso, Slawomir Gonkowski
Summary: This study evaluated the exposure of 30 dogs to six selected PFASs through the analysis of fur samples, with all PFASs detected in the canine fur samples. No statistically significant differences were found based on gender, age, and body weight of the animals. The study confirmed the suitability of fur samples for biomonitoring of PFASs exposure in domestic animals.
ENVIRONMENTAL POLLUTION
(2021)
Article
Chemistry, Analytical
John MacInnis, Amila O. De Silva, Igor Lehnherr, Derek C. G. Muir, Kyra A. St Pierre, Vincent L. St Louis, Christine Spencer
Summary: The study found that melting snow and ice increased PFAS concentrations in Lake Hazen, while river water from non-glacial freshwater continuum was identified as a major source of contamination. Additionally, the distribution of PFAS in vegetation and soil changed as water flowed downstream.
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
(2022)
Article
Engineering, Environmental
Yunqiao Zhou, Bin Shi, Ran Bi, Xiaoping Wang, Lu Yang, Tieyu Wang, Jing Meng
Summary: Increased anthropogenic activities have caused contamination of PFASs in lakes worldwide. This study conducted research in Baiyangdian Lake, China, and found that the average concentrations of PFASs have increased significantly. The water phase is the primary transport path for PFASs, and the exchange flux between water and sediment is high.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Environmental Sciences
Melvin S. Samuel, Mingwei Shang, Junjie Niu
Summary: The developed f-TMO hybrid photocatalyst shows efficient removal of various PFAS contaminants in water with high adsorption capacity and defluorination rate, making it promising for applications in residential and industrial water systems.
Article
Biochemical Research Methods
Thierry Delatour, Xanthippe Theurillat, Bjorn Eriksen, Claudia Mujahid, Pascal Mottier
Summary: Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is widely used for the quantitative determination of per- and polyfluoroalkyl substances (PFAS) in foodstuff. This article highlights the diversity in LOQ definitions used in LC-MS/MS methods and raises concerns about the reliability of some of these methods in generating data requested by the European regulation. The importance of using PFAS-free samples spiked with the analyte(s) of interest and applying identification criteria according to official documents for accurate LOQ measurement is emphasized.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY
(2023)
Article
Environmental Sciences
Kuan-Yu Kuo, Yu Chen, Yi Chuang, Pinpin Lin, Yi-Jun Lin
Summary: This study investigated the health risks of perfluoroalkyl substances (PFASs) on pregnant women, infants, and children, with a focus on the mixture risks of the four main PFASs. The findings revealed that PFOS was the most dominant PFAS in the serum of pregnant women and children globally, with potential immune effects exceeding 1. The cumulative hazard quotients (HQs) for developmental and immune effects in infants could also be greater than 1, suggesting concerns for infant development and immunity. The national and global serum database and risk assessment provide additional insights into PFAS exposure and mixture risks in vulnerable populations, serving as a reference for evaluating regulatory mitigation measures.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Engineering, Environmental
Carrie A. McDonough, Wenting Li, Heather N. Bischel, Amila O. De Silva, Jamie C. DeWitt
Summary: Assessing the health risks associated with PFASs is a complex problem that requires collaboration among scientists, risk assessors, and regulators. One pressing question is the significance of pre-PFAAs, which degrade to persistent perfluoroalkyl acids, in human exposure and health risk assessment. This article provides an overview of recent progress and recommendations to broaden the understanding of PFAS exposure by considering the pre-PFAA subclass.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Chemistry, Analytical
Bailey B. B. Bowers, Zimo Lou, Jiang Xu, Amila O. O. De Silva, Xinhua Xu, Gregory V. V. Lowry, Ryan C. C. Sullivan
Summary: Per- and polyfluoroalkyl substances (PFAS) are widely used in consumer applications and are found in drinking water, posing a threat to human health. Reduction via the hydrated electron is a promising technology for PFAS remediation, but previous studies often lack fluorine atom balances and rely on suspect screening. In this study, non-target analysis was performed on PFAS solutions treated with UV/sulfite, revealing unexpected transformation products and the need for further investigation.
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS
(2023)
Article
Environmental Sciences
Lies Teunen, Lieven Bervoets, Claude Belpaire, Maarten De Jonge, Thimo Groffen
Summary: Despite specific restrictions, PFAS are still present in aquatic ecosystems in Flanders, Belgium. Biomonitoring studies found different PFAS concentrations and profiles in indigenous fish and translocated mussels, showing biomagnification of some PFAS in the food chain and biodilution of others. Human health risk was identified for eels, while ecological risk of PFOS exceeded standards at around half of the sampling locations.
ENVIRONMENTAL SCIENCES EUROPE
(2021)
Article
Environmental Sciences
Yu-Hsuan Shih, Annelise J. Blomberg, Louise Helskov Jorgensen, Pal Weihe, Philippe Grandjean
Summary: This study found significant associations between PFAS concentrations at 18 months, 5 years, and 9 years, and levels of leptin, leptin receptor, and resistin in children at age 9. There was limited evidence of a modification effect of sex on serum PFAS concentrations. The Bayesian kernel machine regression results consistently suggested significant effects of PFAS mixtures at 18 months, 5 years, and 9 years on adipokine concentrations at 9 years.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Hong T. M. Nguyen, Sandra Nilsson, Ava A. R. Mueller, Leisa-Maree Toms, Carl Kennedy, Daman Langguth, Peter Hobson, Jochen F. Mueller
Summary: Human biomonitoring programs have been conducted worldwide to assess the exposure and health risks of per- and polyfluoroalkyl substances (PFAS). This study provided the first evidence of PFAS exposure in the population of Papua New Guinea, a unique region both socioeconomically and geographically. The detected PFAS concentrations were lower than those in serum pools obtained from Australia, but the presence of 9Cl-F53B in all pools suggests exposure from local industrial sources.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Review
Environmental Sciences
Sipra Nayak, Gunanidhi Sahoo, Ipsita Iswari Das, Aman Kumar Mohanty, Rajesh Kumar, Lakshman Sahoo, Jitendra Kumar Sundaray
Summary: Poly- and perfluoroalkyl substances (PFASs) are anthropogenic chemicals with a fluorinated carbon chain and have gained global attention due to their durability, bioaccumulation potential, and negative impacts on living organisms. The negative impacts of PFASs on aquatic ecosystems are concerning due to their widespread use and constant leakage into the water environment. PFASs can alter the bioaccumulation and toxicity of certain substances, causing a variety of negative consequences in aquatic organisms. PFAS bioaccumulation affects the composition of the intestinal microbiota, which is related to the well-being of the host. PFASs act as endocrine disruptors and can result in dysbiosis of gut microbes and other health repercussions.
Article
Environmental Sciences
Samira Salihovic, Jordan Stubleski, Anna Karrman, Anders Larsson, Tove Fall, Lars Lind, P. Monica Lind
ENVIRONMENT INTERNATIONAL
(2018)
Article
Environmental Sciences
P. Monica Lind, Samira Salihovic, Lars Lind
ENVIRONMENT INTERNATIONAL
(2018)
Article
Environmental Sciences
Ingrid Mobacke, Lars Lind, Linda Dunder, Samira Salihovic, P. Monica Lind
ENVIRONMENT INTERNATIONAL
(2018)
Article
Environmental Sciences
P. Monica Lind, Samira Salihovic, Jordan Stubleski, Anna Karrman, Lars Lind
ENVIRONMENTAL HEALTH
(2018)
Article
Environmental Sciences
M. A. La Merrill, P. M. Lind, S. Salihovic, B. van Bavel, L. Lind
ENVIRONMENTAL RESEARCH
(2018)
Article
Environmental Sciences
Samira Salihovic, Tove Fall, Andrea Ganna, Corey D. Broeckling, Jessica E. Prenni, Tuulia Hyotylainen, Anna Karrman, P. Monica Lind, Erik Ingelsson, Lars Lind
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
(2019)
Editorial Material
Environmental Sciences
Saroj Jayasinghe, Lars Lind, Samira Salihovic, Anders Larsson, P. Monica Lind
SCIENCE OF THE TOTAL ENVIRONMENT
(2019)
Article
Environmental Sciences
S. Salihovic, L. Lind, A. Larsson, P. M. Lind
ENVIRONMENT INTERNATIONAL
(2020)
Article
Cardiac & Cardiovascular Systems
Lars Lind, Samira Salihovic, Johan Sundstrom, Corey D. Broeckling, Patrik K. Magnusson, Jessica Prenni, Tove Fall, Johan Arnlov
Summary: Using plasma metabolomics, a novel biomarker for atrial fibrillation, 9-decenoylcarnitine, was identified. However, it is likely not causally related to atrial fibrillation.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Environmental Sciences
P. Monica Lind, Lars Lind, Samira Salihovic, Hakan Ahlstrom, Karl Michaelsson, Joel Kullberg, Robin Strand
Summary: According to this study, some PFAS are inversely related to fat mass, but not all PFAS show this relationship, and it mainly occurs in women.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Linda Dunder, P. Monica Lind, Samira Salihovic, Jordan Stubleski, Anna Karrman, Lars Lind
Summary: This study investigated the associations between multiple PFAS and blood lipids in a longitudinal manner. The results showed that changes in six out of the eight investigated PFAS were positively associated with changes in plasma lipids, providing further evidence for the role of PFAS exposure in human lipid metabolism.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Marianne Haug, Linda Dunder, P. Monica Lind, Lars Lind, Samira Salihovic
Summary: This study found associations between plasma PFAS concentrations and cholesterol, lipoproteins, and fatty acids, suggesting a potential role of PFAS in lipid metabolism.
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
(2023)
Article
Environmental Sciences
Linda Dunder, Samira Salihovic, Georgios Varotsis, Monica Lind, Solve Elmstahl, Lars Lind
Summary: This study conducted in Sweden using data from two population-based cohort studies found that moderately elevated levels of PFAS do not increase the risk of cardiovascular disease. The meta-analysis results indicated a modest inverse association between PFOA levels and incident CVD, further supporting that increasing PFAS levels are not linked to an increased risk of CVD.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Medicine, General & Internal
P. Monica Lind, Samira Salihovic, Jordan Stubleski, Anna Karrman, Lars Lind