Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site
出版年份 2021 全文链接
标题
Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site
作者
关键词
-
出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 118, Issue 9, Pages e2021847118
出版商
Proceedings of the National Academy of Sciences
发表日期
2021-02-23
DOI
10.1073/pnas.2021847118
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Dolastatin 15 from a Marine Cyanobacterium Suppresses HIF‐1α Mediated Cancer Cell Viability and Vascularization
- (2020) Ranjala Ratnayake et al. CHEMBIOCHEM
- Microtubule-targeting agents and their impact on cancer treatment
- (2020) Vladimír Čermák et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Marine Cyanobacteria: A Source of Lead Compounds and their Clinically-Relevant Molecular Targets
- (2020) Lik Tong Tan et al. MOLECULES
- Structural Basis of Noscapine Activation for Tubulin Binding
- (2020) María A. Oliva et al. JOURNAL OF MEDICINAL CHEMISTRY
- A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin
- (2018) Grégory Menchon et al. Nature Communications
- An Emerging Role for Tubulin Isotypes in Modulating Cancer Biology and Chemotherapy Resistance
- (2017) Amelia L. Parker et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons
- (2017) Tobias Weinert et al. Nature Communications
- Multidimensional Screening Platform for Simultaneously Targeting Oncogenic KRAS and Hypoxia-Inducible Factors Pathways in Colorectal Cancer
- (2016) Michelle S. Bousquet et al. ACS Chemical Biology
- Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes
- (2016) Harinath Doodhi et al. CURRENT BIOLOGY
- Pironetin Binds Covalently to αCys316 and Perturbs a Major Loop and Helix of α-Tubulin to Inhibit Microtubule Formation
- (2016) Andrea E. Prota et al. JOURNAL OF MOLECULAR BIOLOGY
- Diverted Total Synthesis of Promysalin Analogs Demonstrates That an Iron-Binding Motif Is Responsible for Its Narrow-Spectrum Antibacterial Activity
- (2016) Andrew D. Steele et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery
- (2015) Yuxi Wang et al. FEBS Journal
- Targeted Natural Products Discovery from Marine Cyanobacteria Using Combined Phylogenetic and Mass Spectrometric Evaluation
- (2015) Lilibeth A. Salvador-Reyes et al. JOURNAL OF NATURAL PRODUCTS
- Evaluation of class I HDAC isoform selectivity of largazole analogues
- (2014) Bumki Kim et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs
- (2014) A. E. Prota et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis of tubulin tyrosination by tubulin tyrosine ligase
- (2013) Andrea E. Prota et al. JOURNAL OF CELL BIOLOGY
- Hydroxamate, a Key Pharmacophore Exhibiting a Wide Range of Biological Activities
- (2013) Samuel Bertrand et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Total synthesis of (+)-A83586C, (+)-kettapeptin and (+)-azinothricin: powerful new inhibitors of β-catenin/TCF4- and E2F-mediated gene transcription
- (2010) Karl J. Hale et al. CHEMICAL COMMUNICATIONS
- The Legumain Protease-Activated Auristatin Prodrugs Suppress Tumor Growth and Metastasis without Toxicity
- (2010) Krishna Mohan Bajjuri et al. ChemMedChem
- Fluorous TaggedN-Hydroxy Phthalimide for the Parallel Synthesis ofO-Aryloxyamines
- (2010) Florence S. Gaucher-Wieczorek et al. JOURNAL OF COMBINATORIAL CHEMISTRY
- Intramolecular Modulation of Serine Protease Inhibitor Activity in a Marine Cyanobacterium with Antifeedant Properties
- (2010) Susan Matthew et al. Marine Drugs
- Design, Synthesis, and Biological Evaluation of EF- and ABEF- Analogues of (+)-Spongistatin 1
- (2010) Amos B. Smith et al. ORGANIC LETTERS
- Phylogenetic and Chemical Diversity of Three Chemotypes of Bloom-Forming Lyngbya Species (Cyanobacteria: Oscillatoriales) from Reefs of Southeastern Florida
- (2009) K. Sharp et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Antivascular Actions of Microtubule-Binding Drugs
- (2009) E. L. Schwartz CLINICAL CANCER RESEARCH
- Total Synthesis of (+)-Azinothricin and (+)-Kettapeptin
- (2009) Karl J. Hale et al. ORGANIC LETTERS
- Tiglicamides A–C, cyclodepsipeptides from the marine cyanobacterium Lyngbya confervoides
- (2009) Susan Matthew et al. PHYTOCHEMISTRY
- Largamides A–C, Tiglic Acid-Containing Cyclodepsipeptides with Elastase-Inhibitory Activity from the Marine CyanobacteriumLyngbya confervoides
- (2009) Susan Matthew et al. PLANTA MEDICA
- The Taccalonolides: Microtubule Stabilizers That Circumvent Clinically Relevant Taxane Resistance Mechanisms
- (2008) April L. Risinger et al. CANCER RESEARCH
- Pompanopeptins A and B, new cyclic peptides from the marine cyanobacterium Lyngbya confervoides
- (2008) Susan Matthew et al. TETRAHEDRON
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now