Article
Environmental Sciences
Andrea L. Deierlein, Haotian Wu, Allan C. Just, Allison J. Kupsco, Joseph M. Braun, Emily Oken, Diana C. Soria-Contreras, Alejandra Cantoral, Ma Luisa Pizano, Nia McRae, Martha M. Tellez-Rojo, Robert O. Wright, Andrea A. Baccarelli
Summary: The study found that prenatal exposure to phthalates was negatively associated with gestational weight gain and positively associated with long-term changes in maternal weight. Further investigation is needed to understand how phthalates influence body composition and whether they contribute to the development of obesity and other cardiometabolic diseases in women.
ENVIRONMENTAL RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Andrea Maugeri, Roberta Magnano San Lio, Maria Clara La Rosa, Giuliana Giunta, Marco Panella, Antonio Cianci, Maria Anna Teresa Caruso, Antonella Agodi, Martina Barchitta
Summary: Inadequate gestational weight gain could affect fetal health and is associated with DNA telomere length.
Article
Environmental Sciences
Helen Zukin, Brenda Eskenazi, Nina Holland, Kim G. Harley
Summary: In a study of 415 pregnant Latina women, prenatal phthalate levels were not associated with hyperglycemia, impaired glucose tolerance, or gestational diabetes. However, there was an increased risk of excessive gestational weight gain.
ENVIRONMENTAL RESEARCH
(2021)
Article
Environmental Sciences
Diana C. Pacyga, Marisa A. Patti, George D. Papandonatos, Diana K. Haggerty, Antonia M. Calafat, Joseph C. Gardiner, Joseph M. Braun, Susan L. Schantz, Rita S. Strakovsky
Summary: This study investigated the associations of individual and cumulative phthalate/replacement biomarkers with gestational weight gain (GWG). The results showed that biomarkers of phthalates/replacements were fetal sex-specifically associated with GWGz. This study suggests the need for additional research on the plasticizer replacement in pregnant women.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Medicine, General & Internal
Kamini Dangat, Sanjay Gupte, Girija Wagh, Sanjay Lalwani, Karuna Randhir, Shweta Madiwale, Hemlata Pisal, Vrushali Kadam, Shridevi Gundu, Nomita Chandhiok, Bharati Kulkarni, Sadhana Joshi, Caroline Fall, Harshpal Singh Sachdev
Summary: This study aimed to evaluate the trimester specific gestational weight gain (GWG) in Indian pregnant women and compare it with international and Indian reference data. The study found that Indian women had lower GWG compared to international standards, but higher GWG compared to Indian reference data. Maternal BMI, age, parity, hemoglobin concentrations, and height were found to be associated with GWG.
FRONTIERS IN MEDICINE
(2022)
Article
Endocrinology & Metabolism
Xiaoli Gong, Jiaxin Li, Yuanhui Jiang, Pengbo Yuan, Lian Chen, Yike Yang, You Li, Mengxing Sun, Yangyu Zhao, Huifeng Shi, Yuan Wei
Summary: This study aimed to evaluate the impact of gestational weight gain (GWG) on the risk of preeclampsia among women with different prepregnancy body mass index (BMI). The findings showed that high prepregnancy BMI and excessive GWG were associated with an increased risk of preeclampsia.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Medical Laboratory Technology
Wenlin Bai, Hui Wang, Ruiling Fang, Mengwen Lin, Yao Qin, Hongjuan Han, Jing Cui, Rong Zhang, Yifei Ma, Durong Chen, Wenping Zhang, Li Wang, Hongmei Yu
Summary: The effect of abnormal OGTT0h+1h+2h on macrosomia was significantly greater than other OGTT characteristics, especially for those with pre-pregnancy BMI >= 24 kg/m2.
CLINICA CHIMICA ACTA
(2023)
Review
Nutrition & Dietetics
Reyna Samano, Hugo Martinez-Rojano, Luis Ortiz-Hernandez, Oralia Najera-Medina, Gabriela Chico-Barba, Ricardo Gamboa, Maria Eugenia Mendoza-Flores
Summary: About 56% to 84% of pregnant adolescents experience inappropriate gestational weight gain. This scoping review aimed to synthesize the available scientific evidence on the association of individual, family, and social factors with gestational weight gain in pregnant adolescents. The evidencesuggests that pre-pregnancy body mass index (pBMI) is positively associated with gestational weight gain, but insufficient evidence exists for other factors.
Article
Nutrition & Dietetics
Xuemei Hao, Jingru Lu, Shuangqin Yan, Fangbiao Tao, Kun Huang
Summary: Maternal pre-pregnancy overweight and excessive gestational weight gain are associated with decreased cognitive development in children, particularly in terms of intelligence and verbal comprehension. Adequate gestational weight gain in mothers with pre-pregnancy underweight is beneficial for children's cognition, while excessive weight gain is linked to a decrease in children's full-scale intelligence quotient.
Article
Medicine, General & Internal
Stefanie N. Hinkle, Sunni L. Mumford, Katherine L. Grantz, Pauline Mendola, James L. Mills, Edwina H. Yeung, Anna Z. Pollack, Sonia M. Grandi, Rajeshwari Sundaram, Yan Qiao, Enrique F. Schisterman, Cuilin Zhang
Summary: Gestational weight change is associated with mortality over 50 years later, with sustained excessive or reduced weight being associated with increased risk of cardiovascular and diabetes-related deaths.
Article
Obstetrics & Gynecology
P. M. Y. Lee, L. A. Tse, K. D. Laszlo, D. Wei, Y. Yu, J. Li
Summary: The study found an association between maternal gestational weight gain and offspring's intellectual developmental disorders, which may be modified by maternal early-pregnancy BMI.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Article
Nutrition & Dietetics
Momoka Ito, Hyo Kyozuka, Tomoko Yamaguchi, Misa Sugeno, Tsuyoshi Murata, Tsuyoshi Hiraiwa, Fumihiro Ito, Daisuke Suzuki, Toma Fukuda, Shun Yasuda, Keiya Fujimori, Yasuhisa Nomura
Summary: The relationship between weight gain during pregnancy and hypertensive disorders of pregnancy in women with pre-pregnancy obesity is unclear. This study found that weight gain during pregnancy has an effect on hypertensive disorders of pregnancy among women with a pre-pregnancy BMI of 25.0 kg/m(2). The results suggest that controlling weight gain during pregnancy can help reduce the risk of hypertensive disorders of pregnancy in obese women.
Article
Environmental Sciences
Tamarra James-Todd, Marta Ponzano, Andrea Bellavia, Paige L. Williams, David E. Cantonwine, Antonia M. Calafat, Russ Hauser, Marlee R. Quinn, Ellen W. Seely, Thomas F. McElrath
Summary: The study demonstrates a link between phthalate exposures during pregnancy and gestational diabetes mellitus. The metabolites of these chemicals were found to be associated with maternal glucose intolerance, suggesting both long-term and short-term health implications.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Nutrition & Dietetics
Ellen Aagaard Nohr, Sanne Wolff, Helene Kirkegaard, Chunsen Wu, Anne-Marie Nybo Andersen, Jorn Olsen, Bodil Hammer Bech
Summary: Maternal obesity is associated with an increased risk of stillbirth and neonatal death, particularly due to causes related to vascular and metabolic disturbances. Additionally, low early gestational weight gain in women of normal weight may also contribute to unexplained intrauterine death.
Article
Endocrinology & Metabolism
Marie Parfaite Uwimana Muhuza, Lixia Zhang, Qi Wu, Lu Qi, Danqing Chen, Zhaoxia Liang
Summary: This study investigated the association between HbA1c levels and adverse outcomes in women with gestational diabetes mellitus (GDM), considering maternal age, pre-pregnancy BMI, and gestational weight gain (GWG). The results showed that HbA1c was significantly associated with macrosomia, pregnancy-induced hypertension (PIH), preterm birth, and primary Cesarean section. The associations varied with maternal age, pre-pregnancy BMI, and GWG.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Environmental Sciences
Stefanie A. Busgang, Syam S. Andra, Paul Curtin, Elena Colicino, Matthew J. Mazzella, Moira Bixby, Alison P. Sanders, John D. Meeker, Marissa Hauptman, Shirisha Yelamanchili, Wanda Phipatanakul, Chris Gennings
Summary: Environmental research often relies on urinary biomarkers which require dilution correction to accurately measure exposures. Specific gravity (SG) and creatinine (UCr) are commonly measured urinary dilution factors. Epidemiologic studies may assess only one of these measures, making it difficult to pool studies that may otherwise be able to be combined.
ENVIRONMENTAL RESEARCH
(2023)
Article
Geochemistry & Geophysics
Tian-Yi Huang, Fang-Zhen Teng, Ze-Zhou Wang, Yong-Sheng He, Zhi-Chao Liu, Fu-Yuan Wu
Summary: To understand the behavior of K isotopes during granitic magmatic differentiation, high-precision K isotope data for bulk granitoids and their K-bearing minerals from the Dabie and Himalayan orogens in China were analyzed. The study found significant variations in K isotopic compositions among different minerals, indicating compositional control on isotope fractionations. The research suggests that K isotopes can be a potential tool for studying the differentiation of felsic magmas.
GEOCHIMICA ET COSMOCHIMICA ACTA
(2023)
Article
Clinical Neurology
Magdalena Zebrowska, Susanne Strohmaier, Carri Westgarth, Curtis Huttenhower, Astrid C. Erber, Shahab Haghayegh, A. Heather Eliassen, Tianyi Huang, Francine Laden, Jaime E. Hart, Bernard Rosner, Ichiro Kawachi, Jorge E. Chavarro, Olivia I. Okereke, Eva S. Schernhammer
Summary: In this longitudinal study, no association was found between pet ownership and adolescent depression overall. However, subgroup analyses suggest that some individuals may benefit from having a pet in terms of their mental health.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Oncology
Farnoosh Abbas-Aghababazadeh, Naoko Sasamoto, Mary K. Townsend, Tianyi Huang, Kathryn L. Terry, Allison F. Vitonis, Kevin M. Elias, Elizabeth M. Poole, Jonathan L. Hecht, Shelley S. Tworoger, Brooke L. Fridley
Summary: A prediction model for optimal debulking in ovarian cancer was developed based on pre-diagnosis epidemiologic factors and tumor markers. Results showed that current aspirin use was associated with lower odds of optimal debulking, while ADRB2 and FAP markers were associated with increased odds of optimal debulking.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Daniel W. Cramer, Allison F. Vitonis, Tianyi Huang, Amy L. Shafrir, A. Heather Eliassen, Robert L. Barbieri, Susan E. Hankinson
Summary: This study found that longer lifetime ovulatory years (LOY) are associated with higher testosterone levels and higher estradiol levels, which may explain why longer LOY increases the risk for breast, endometrial, and ovarian cancer.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2023)
Article
Environmental Sciences
P. A. Bommarito, D. R. Stevens, B. M. Welch, D. Weller, J. D. Meeker, D. E. Cantonwine, T. F. McElrath, K. K. Ferguson
Summary: This study analyzed data from 900 singleton pregnancies in the LIFECODES Fetal Growth Study and found that exposure to phthalate replacements and bisphenol S increased, while exposure to phthalates and most phenols decreased. The study also found that the levels of chemical exposures varied with sociodemographic characteristics, with higher concentrations observed in non-Hispanic Black or Hispanic participants.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Endocrinology & Metabolism
Sina Kianersi, Susan Redline, Morgana Mongraw-Chaffin, Tianyi Huang
Summary: In this study, it was found through cross-sectional and prospective analyses that a higher proportion and longer duration of N3 sleep were associated with a reduced risk of type 2 diabetes.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Psychology, Clinical
Shanlin Ke, Anne-Josee Guimond, Shelley S. Tworoger, Tianyi Huang, Andrew T. T. Chan, Yang-Yu Liu, Laura D. D. Kubzansky
Summary: This study found that emotions and emotion regulation strategies are associated with the gut microbiome composition and functional pathways. Positive emotions were linked with certain bacterial populations, while negative emotions were correlated with the abundance of the same species. Moreover, negative emotions were also inversely related to specific metabolic pathways. These findings underscore the importance of considering the gut microbiome in understanding the role of emotions in physical health.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Reproductive Biology
Theresa M. Boyer, Paige A. Bommarito, Barrett M. Welch, John D. Meeker, Tamarra James-Todd, David E. Cantonwine, Thomas F. McElrath, Kelly K. Ferguson
Summary: Excessive gestational weight gain can lead to adverse maternal and neonatal outcomes. This study explores the association between maternal exposure to phthalates and altered gestational weight gain. The findings suggest that phthalates may be related to higher gestational weight gain, especially among individuals with pre-pregnancy obesity. Further research should investigate the sensitivity to phthalate exposures in pregnant people with obesity.
REPRODUCTIVE TOXICOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Kelsie M. M. Full, Tianyi Huang, Neomi A. A. Shah, Matthew A. A. Allison, Erin D. D. Michos, Daniel A. A. Duprez, Susan Redline, Pamela L. L. Lutsey
Summary: This study examined the association between sleep regularity and subclinical atherosclerosis. The results showed that irregular sleep duration and sleep timing were associated with early-stage atherosclerosis. Participants with greater sleep duration irregularity and irregular sleep timing were more likely to have high coronary artery calcium burden and abnormal ankle-brachial index.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Medicine, General & Internal
Sina Kianersi, Yue Liu, Marta Guasch-Ferre, Susan Redline, Eva Schernhammer, Qi Sun, Tianyi Huang
Summary: Evening chronotype is associated with unhealthy lifestyle and increased risk of diabetes, but adjustment for factors like BMI, physical activity, and diet quality can attenuate some of this risk.
ANNALS OF INTERNAL MEDICINE
(2023)
Article
Environmental Sciences
Astrid N. Zamora, Erica C. Jansen, Jaclyn M. Goodrich, Martha M. Tellez-Rojo, Peter X. K. Song, John D. Meeker, Dana C. Dolinoy, Libni A. Torres-Olascoaga, Alejandra Cantoral, Karen E. Peterson
Summary: This study examines the relationship between endocrine-disrupting chemicals (EDCs) and metabolic syndrome (MetS) risk in adolescents. The findings from the analysis of data from 344 Mexican youths indicate that exposure to EDCs is associated with an increased risk of MetS and lipid abnormalities in adolescents, especially among males.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Ram C. Siwakoti, Amber Cathey, Kelly K. Ferguson, Wei Hao, David E. Cantonwine, Bhramar Mukherjee, Thomas F. McElrath, John D. Meeker
Summary: This study found that prenatal exposure to PFAS may have an impact on pregnancy outcomes, including preterm birth and large-for-gestational age (LGA). However, the effects of PFAS on these outcomes depend on the fetal sex. Specifically, certain PFAS were associated with placental preterm birth, with stronger associations observed in male fetuses. For LGA, different PFAS had different effects in females and males.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Amber Cathey, Marcela Tamayo-Ortiz, Juan Tamayo-Orozco, John D. Meeker, Karen E. Peterson, Belem Trejo-Valdivia, Martha Maria Tellez-Rojo, Deborah J. Watkins
Summary: Phthalates exposure during pregnancy is associated with perinatal bone health, particularly affecting bone remodeling. The study highlights the importance of considering calcium supplementation and body mass index as effect modifiers in understanding the effects of environmental exposures on bone health.
ENVIRONMENTAL RESEARCH
(2023)
Article
Clinical Neurology
Joon Chung, Matthew Goodman, Tianyi Huang, Meredith L. Wallace, Pamela L. Lutsey, Jarvis T. Chen, Cecilia Castro-Diehl, Suzanne Bertisch, Susan Redline
Summary: This study found that better sleep characteristics were associated with a lower risk of mortality. The results suggest that addressing multiple dimensions of sleep may offer novel approaches for improving health.