Plasma trimethylamine N-oxide and its metabolic precursors and risk of mortality, cardiovascular and renal disease in individuals with type 2-diabetes and albuminuria

Utility of Plasma Concentration of Trimethylamine N-Oxide in Predicting Cardiovascular and Renal Complications in Individuals With Type 1 Diabetes

(2019) Signe A. Winther et al.   DIABETES CARE

Elevation of Trimethylamine-N-Oxide in Chronic Kidney Disease: Contribution of Decreased Glomerular Filtration Rate

(2019) Caroline C. Pelletier et al.   Toxins

Trimethylamine N-oxide and incident atherosclerotic events in high-risk individuals with diabetes: an ACCORD trial post hoc analysis

(2019) Andrea Cardona et al.   BMJ Open Diabetes Research & Care

Urinary tubular biomarkers as predictors of kidney function decline, cardiovascular events and mortality in microalbuminuric type 2 diabetic patients

(2018) Viktor Rotbain Curovic et al.   ACTA DIABETOLOGICA

The Association between Plasma Levels of Trimethylamine N-Oxide and the Risk of Coronary Heart Disease in Chinese Patients with or without Type 2 Diabetes Mellitus

(2018) Zengxiang Dong et al.   DISEASE MARKERS

Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential

(2018) Adam B. Roberts et al.   NATURE MEDICINE

Impact of chronic dietary red meat, white meat, or non-meat protein on trimethylamine N-oxide metabolism and renal excretion in healthy men and women

(2018) Zeneng Wang et al.   EUROPEAN HEART JOURNAL

Gut microbe-generated metabolite trimethylamine-N-oxide as cardiovascular risk biomarker: a systematic review and dose-response meta-analysis

(2017) Gabriele Giacomo Schiattarella et al.   EUROPEAN HEART JOURNAL

Intensified multifactorial intervention in type 2 diabetics with microalbuminuria leads to long-term renal benefits

(2017) Jens Oellgaard et al.   KIDNEY INTERNATIONAL

Dietary Choline and Betaine and Risk of CVD: A Systematic Review and Meta-Analysis of Prospective Studies

(2017) Katie Meyer et al.   Nutrients

Plasma Metabolites From Choline Pathway and Risk of Cardiovascular Disease in the PREDIMED (Prevention With Mediterranean Diet) Study

(2017) Marta Guasch‐Ferré et al.   Journal of the American Heart Association

Gut Microbiota Metabolites and Risk of Major Adverse Cardiovascular Disease Events and Death: A Systematic Review and Meta‐Analysis of Prospective Studies

(2017) Yoriko Heianza et al.   Journal of the American Heart Association

Dietary phosphatidylcholine and risk of all-cause and cardiovascular-specific mortality among US women and men

(2016) Yan Zheng et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

(2016) Weifei Zhu et al.   CELL

Increased Trimethylamine N- Oxide Portends High Mortality Risk Independent of Glycemic Control in Patients with Type 2 Diabetes Mellitus

(2016) W. H. Wilson Tang et al.   CLINICAL CHEMISTRY

Years of life gained by multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria: 21 years follow-up on the Steno-2 randomised trial

(2016) Peter Gæde et al.   DIABETOLOGIA

Trimethylamine N‐Oxide Promotes Vascular Inflammation Through Signaling of Mitogen‐Activated Protein Kinase and Nuclear Factor‐κB

(2016) Marcus M. Seldin et al.   Journal of the American Heart Association

Serum Trimethylamine-N-Oxide Is Strongly Related to Renal Function and Predicts Outcome in Chronic Kidney Disease

(2016) Catharina Missailidis et al.   PLoS One

Plasma levels of trimethylamine-N-oxide are confounded by impaired kidney function and poor metabolic control

(2015) Daniel M. Mueller et al.   ATHEROSCLEROSIS

Additive prognostic value of plasma N-terminal pro-brain natriuretic peptide and coronary artery calcification for cardiovascular events and mortality in asymptomatic patients with type 2 diabetes

(2015) Bernt Johan von Scholten et al.   Cardiovascular Diabetology

Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis

(2015) Zeneng Wang et al.   CELL

Measurement of trimethylamine-N-oxide by stable isotope dilution liquid chromatography tandem mass spectrometry

(2014) Zeneng Wang et al.   ANALYTICAL BIOCHEMISTRY

Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide

(2014) Z. Wang et al.   EUROPEAN HEART JOURNAL

Decline in Estimated Glomerular Filtration Rate and Subsequent Risk of End-Stage Renal Disease and Mortality

(2014) Josef Coresh et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Changes in Diabetes-Related Complications in the United States, 1990–2010

(2014) Edward W. Gregg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Betaine and Trimethylamine-N-Oxide as Predictors of Cardiovascular Outcomes Show Different Patterns in Diabetes Mellitus: An Observational Study

(2014) Michael Lever et al.   PLoS One

A New Equation to Estimate Glomerular Filtration Rate

(2013) Andrew S. Levey et al.   ANNALS OF INTERNAL MEDICINE

A Combined Epidemiologic and Metabolomic Approach Improves CKD Prediction

(2013) E. P. Rhee et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

Cystatin C versus Creatinine in Determining Risk Based on Kidney Function

(2013) Michael G. Shlipak et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Elevated NT-proBNP and coronary calcium score in relation to coronary artery disease in asymptomatic type 2 diabetic patients with elevated urinary albumin excretion rate

(2011) H. Reinhard et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION