4.4 Article

EQ-5D-Y Value Set for Slovenia

期刊

PHARMACOECONOMICS
卷 39, 期 4, 页码 463-471

出版社

ADIS INT LTD
DOI: 10.1007/s40273-020-00994-4

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资金

  1. European Union [779312]
  2. EuroQol Group (EQ) [20180510]

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This study aimed to obtain adult preferences towards EQ-5D-Y health states in Slovenia, following the international valuation protocol EQ-5D-Y-3L. The study provided the first EQ-5D-Y value set in the world, addressing an important research gap.
Background A value set for the EuroQoL 5-Dimensions (EQ-5D)-Y in Slovenia is not yet available, making the calculation of quality-adjusted life-years (QALYs) for children and adolescents using this generic instrument impossible. Objective The main objective of our study was to obtain adult preferences towards EQ-5D-Y health states in Slovenia, following the EQ-5D-Y-3L international valuation protocol. The adults were asked to take the perspective of a hypothetical 10-year-old child. Method A sample of 1074 adults in Slovenia completed an online discrete-choice experiment (DCE) survey on EQ-5D-Y health states. The latent scale issue was addressed by obtaining the value of the anchor (33333) with 200 composite time trade-off (cTTO) interviews. A mixed (random coefficients) logit model was used to estimate the value set. Results All the estimated coefficients of the mixed logit model were statistically significant at the 1% level and had an expected negative sign. The most important health dimension in EQ-5D-Y is pain/discomfort, followed by anxiety/depression, usual activities, and mobility, with self-care being the least important health dimension. Conclusions The study addresses an important research gap and presents the EQ-5D-Y value set for Slovenia. At the time of writing, no published value sets are available for the EQ-5D-Y-3L appropriate for use in QALY calculations, making this value set the first EQ-5D-Y value set in the world.

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