Cancer-associated fibroblast secretion of PDGFC promotes gastrointestinal stromal tumor growth and metastasis
出版年份 2021 全文链接
标题
Cancer-associated fibroblast secretion of PDGFC promotes gastrointestinal stromal tumor growth and metastasis
作者
关键词
-
出版物
ONCOGENE
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-02-20
DOI
10.1038/s41388-021-01685-w
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Avapritinib: First Approval
- (2020) Sohita Dhillon DRUGS
- Ripretinib: First Approval
- (2020) Sohita Dhillon DRUGS
- Avapritinib in advanced PDGFRA D842V-mutant gastrointestinal stromal tumour (NAVIGATOR): a multicentre, open-label, phase 1 trial
- (2020) Michael C Heinrich et al. LANCET ONCOLOGY
- Switch Control Inhibition of KIT and PDGFRA in Patients With Advanced Gastrointestinal Stromal Tumor: A Phase I Study of Ripretinib
- (2020) Filip Janku et al. JOURNAL OF CLINICAL ONCOLOGY
- Resistance to avapritinib in PDGFRA-driven GIST is caused by secondary mutations in the PDGFRA kinase domain
- (2020) Susanne Grunewald et al. Cancer Discovery
- Differential immune profiles distinguish the mutational subtypes of gastrointestinal stromal tumor
- (2019) Gerardo A. Vitiello et al. JOURNAL OF CLINICAL INVESTIGATION
- GPR68, a proton-sensing GPCR, mediates interaction of cancer-associated fibroblasts and cancer cells
- (2018) Shu Z. Wiley et al. FASEB JOURNAL
- Stromal protein βig-h3 reprogrammes tumour microenvironment in pancreatic cancer
- (2018) Delphine Goehrig et al. GUT
- Fibroblast drug scavenging increases intratumoural gemcitabine accumulation in murine pancreas cancer
- (2017) E Hessmann et al. GUT
- Platelet-derived growth factor-C promotes human melanoma aggressiveness through activation of neuropilin-1
- (2017) Federica Ruffini et al. Oncotarget
- Platelet Derived Growth Factor Alpha (PDGFRα) Induces the Activation of Cardiac Fibroblasts by Activating c-Kit
- (2017) Lexun Wang et al. MEDICAL SCIENCE MONITOR
- EMT: 2016
- (2016) M. Angela Nieto et al. CELL
- Combination of Imatinib Mesylate and AKT Inhibitor Provides Synergistic Effects in Preclinical Study of Gastrointestinal Stromal Tumor
- (2016) Phillip Zook et al. CLINICAL CANCER RESEARCH
- FGFR1 and NTRK3 actionable alterations in “Wild-Type” gastrointestinal stromal tumors
- (2016) Eileen Shi et al. Journal of Translational Medicine
- Platelet derived growth factor receptor alpha mediates nodal metastases in papillary thyroid cancer by driving the epithelial-mesenchymal transition
- (2016) Esther Ekpe-Adewuyi et al. Oncotarget
- Molecular Subtypes ofKIT/PDGFRAWild-Type Gastrointestinal Stromal Tumors
- (2016) Sosipatros A. Boikos et al. JAMA Oncology
- Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1
- (2015) Yujiro Hayashi et al. GASTROENTEROLOGY
- KITandPDGFRAMutations and the Risk of GI Stromal Tumor Recurrence
- (2015) Heikki Joensuu et al. JOURNAL OF CLINICAL ONCOLOGY
- Phosphoinositide 3-Kinase Inhibitors Combined with Imatinib in Patient-Derived Xenograft Models of Gastrointestinal Stromal Tumors: Rationale and Efficacy
- (2014) T. Van Looy et al. CLINICAL CANCER RESEARCH
- Fibroblast heterogeneity in the cancer wound
- (2014) Daniel Öhlund et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Optimizing Surgical and Imatinib Therapy for the Treatment of Gastrointestinal Stromal Tumors
- (2013) Jason K. Sicklick et al. JOURNAL OF GASTROINTESTINAL SURGERY
- Anti-KIT monoclonal antibody inhibits imatinib-resistant gastrointestinal stromal tumor growth
- (2013) Badreddin Edris et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Potent Combination of the Novel PI3K Inhibitor, GDC-0941, with Imatinib in Gastrointestinal Stromal Tumor Xenografts: Long-Lasting Responses after Treatment Withdrawal
- (2012) G. Floris et al. CLINICAL CANCER RESEARCH
- Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial
- (2012) George D Demetri et al. LANCET
- Twist1-Induced Invadopodia Formation Promotes Tumor Metastasis
- (2011) Mark A. Eckert et al. CANCER CELL
- A phase I-II study of everolimus (RAD001) in combination with imatinib in patients with imatinib-resistant gastrointestinal stromal tumors
- (2010) P. Schoffski et al. ANNALS OF ONCOLOGY
- Ligand-Dependent Platelet-Derived Growth Factor Receptor (PDGFR)- Activation Sensitizes Rare Lung Cancer and Sarcoma Cells to PDGFR Kinase Inhibitors
- (2009) U. McDermott et al. CANCER RESEARCH
- Molecular Pathobiology of Gastrointestinal Stromal Sarcomas
- (2008) Christopher L. Corless et al. Annual Review of Pathology-Mechanisms of Disease
- Carcinoma-Associated Fibroblast-Like Differentiation of Human Mesenchymal Stem Cells
- (2008) P. J. Mishra et al. CANCER RESEARCH
- Paracrine Signaling by Platelet-Derived Growth Factor-CC Promotes Tumor Growth by Recruitment of Cancer-Associated Fibroblasts
- (2008) C. Anderberg et al. CANCER RESEARCH
- Phase III Randomized, Intergroup Trial Assessing Imatinib Mesylate At Two Dose Levels in Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Expressing the Kit Receptor Tyrosine Kinase: S0033
- (2008) Charles D. Blanke et al. JOURNAL OF CLINICAL ONCOLOGY
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