Article
Psychology, Biological
Lachlan Hall, Amy Dawel, Lisa-Marie Greenwood, Conal Monaghan, Kevin Berryman, Bradley N. Jack
Summary: This study investigated the statistical power of ERP studies based on N1, Tb, and P2 components using Monte Carlo simulations. The results showed that increasing the number of trials, number of participants, and effect magnitude can enhance the statistical power. It was also found that within-subject designs require fewer trials and participants to achieve the same statistical power than between-subject designs.
Article
Psychiatry
Prune Mazer, Ines Macedo, Tiago O. Paiva, Fernando Ferreira-Santos, Rita Pasion, Fernando Barbosa, Pedro Almeida, Celeste Silveira, Cassilda Cunha-Reis, Joao Marques-Teixeira
Summary: The study used a roving paradigm to assess the modulation and habituation of N1 and P2 to simple and complex sounds in first-episode schizophrenia patients and healthy participants. The results showed that patients exhibited abnormal habituation to bird songs, while showing preserved auditory processing of human voices.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Anatomy & Morphology
Maryam Ziaei, Lena Oestreich, David C. Reutens, Natalie C. Ebner
Summary: Empathy changes across adulthood with cognitive components declining with age, while affective empathy findings are mixed. Older adults show more involvement of salience network regions in cognitive empathy to negative emotions, while both younger and older adults recruit a similar brain network for affective empathy to positive emotions. Structural microstructure of the posterior cingulum bundle is related to activation of default mode regions during affective empathy for positive emotions in both age groups.
BRAIN STRUCTURE & FUNCTION
(2021)
Article
Psychology, Biological
Thijs van Laarhoven, Jeroen J. Stekelenburg, Jean Vroomen
Summary: This study investigated the impact of temporal and identity predictability on the suppression of auditory N1 by visual anticipatory motion. The results showed that N1 suppression was largest when the video reliably predicted both the timing and identity of the sound, indicating that both timing and identity predictions are essential elements for predictive coding in audition.
Article
Neurosciences
Shruti Dave, Trevor Brothers, Liv J. Hoversten, Matthew J. Traxler, Tamara Y. Swaab
Summary: This study examined the flexibility of prediction in young and older adults regarding global contextual cues. Young adults were able to adapt local predictive processes based on cues provided by the global communicative environment, while older adults did not show the same flexibility. Cognitive control played a crucial role in mediating age-related reductions in sensitivity to global contextual cues.
Article
Clinical Neurology
Bowen Xiu, Christopher Andanty, Nasia Dai, Clement C. Zai, Ariel Graff, Heather McNeely, Zafiris J. Daskalakis, Vincenzo De Luca
Summary: The study found that neuroticism is associated with the visual N100 and P200 event-related potentials components related to attention, with high neuroticism subjects showing increased P200 amplitude and latency in the frontal and parietal regions.
CLINICAL EEG AND NEUROSCIENCE
(2022)
Article
Psychology, Biological
Haoran Dou, Yuqian Dai, Yiwen Qiu, Yi Lei
Summary: The study found that attachment voices have an impact on the expectancy of unconditioned stimuli and EEG responses during fear conditioning, especially in the case of safety signals. Responses to CS+ and CS- differed more when participants heard their partner's voice, even as pure vowel sounds, enhancing the acquisition of conditioned safety signals.
Article
Audiology & Speech-Language Pathology
Melissa A. Papesh, Alyssa A. Stefl, Frederick J. Gallun, Curtis J. Billings
Summary: The study aimed to investigate auditory performance and cognitive responses in blast-exposed Veterans, revealing that they reported more auditory difficulties but did not necessarily perform worse in behavioral tests. The use of complex stimuli and challenging signal contrasts did not improve the detection ability of these differences.
Article
Multidisciplinary Sciences
Elizabeth R. Paitel, Kristy A. Nielson
Summary: The study used event-related potentials (ERPs) to investigate the functional lateralization of conflict monitoring (N200) and inhibitory evaluation (P300) in young and older adults during successful inhibition, revealing differences in activation patterns between the two age groups.
Article
Substance Abuse
Roberto U. Cofresi, Casey B. Kohen, Courtney A. Motschman, Reinout W. Wiers, Thomas M. Piasecki, Bruce D. Bartholow
Summary: The study found that low sensitivity to alcohol is associated with a tendency to attribute bottom-up incentive value to naturally conditioned alcohol cues.
Article
Neurosciences
Lauren Kupis, Zachary T. Goodman, Salome Kornfeld, Stephanie Hoang, Celia Romero, Bryce Dirks, Joseph Dehoney, Catie Chang, R. Nathan Spreng, Jason S. Nomi, Lucina Q. Uddin
Summary: This study examined the intrinsic brain dynamics across the lifespan using resting-state fMRI data. It found that children and older adults were more likely to exhibit brain dynamic patterns associated with poorer cognitive flexibility, highlighting the importance of targeting these networks with cognitive flexibility training.
Article
Psychology, Biological
Elkan G. Akyurek, Gulsen Balta
Summary: This study investigated visual temporal integration, specifically how multiple stimuli appearing in rapid succession are perceived as a single event. The results showed that both intrinsic and extrinsic factors have an interactive effect on integration performance, with distinct effects on the event-related potential components. This study provides important insights into the neural mechanisms underlying temporal integration and its impact on perception of longer episodic events.
Article
Clinical Neurology
Bernd Feige, Chiara Baglioni, Philipp Boehm, Anna Heinrich, Samuel Trumm, Fee Benz, Christoph Nissen, Katharina Domschke, Lukas Frase, Dieter Riemann
Summary: The study found a reduced P2 amplitude in insomnia patients during phasic REM sleep, which was correlated with sleep misperception. Independent component analysis showed that frontal negativity played a key role in this group difference.
Article
Psychology, Biological
Iulia Banica, Grace Allison, Sarah E. Racine, Dan Foti, Anna Weinberg
Summary: Reward processing is crucial for learning and survival, and the Reward Positivity (RewP) can reflect this process. This study examined how internal and external factors modulate neural responses to rewards and whether these responses motivate reward-seeking behavior. The results showed that hunger level and snack liking influenced the magnitude of RewP, and the size of RewP was associated with motivated behavior.
Article
Clinical Neurology
Luisina Gregoret, Anna M. Zamorano, Thomas Graven-Nielsen
Summary: This study investigates the effects of multifocal transcranial direct current stimulation (tDCS) on cortical plasticity in different brain regions. It demonstrates that by targeting the resting-state motor network, multifocal tDCS can reverse attenuated N2-P2 cortical responses during prolonged experimental pain.
Review
Clinical Neurology
Cassandra Morrison, Sheida Rabipour, Frank Knoefel, Christine Sheppard, Vanessa Taler
CURRENT ALZHEIMER RESEARCH
(2018)
Review
Clinical Neurology
Cassandra Morrison, Sheida Rabipour, Vanessa Taler, Christine Sheppard, Frank Knoefel
CURRENT ALZHEIMER RESEARCH
(2019)
Article
Neurosciences
Cassandra Morrison, Farooq Kamal, Vanessa Taler
COGNITIVE NEUROSCIENCE
(2019)
Article
Geriatrics & Gerontology
Cassandra Morrison, Farooq Kamal, Kenneth Campbell, Vanessa Taler
NEUROBIOLOGY OF AGING
(2019)
Article
Behavioral Sciences
Rocio A. Lopez Zunini, Cassandra Morrison, Shanna Kousaie, Vanessa Taler
Article
Geriatrics & Gerontology
Cassandra Morrison, Farooq Kamal, Kenneth Campbell, Vanessa Taler
NEUROBIOLOGY OF AGING
(2020)
Article
Neuroimaging
Cassandra Morrison, Mahsa Dadar, Neda Shafiee, Sylvia Villeneuve, D. Louis Collins
Summary: Using different methods to define subjective cognitive decline (SCD) can affect the results of volume differences and cognitive decline findings among cognitively normal older adults in this study.
NEUROIMAGE-CLINICAL
(2022)
Article
Neurosciences
Sheida Rabipour, Cassandra Morrison, Jessica Crompton, Marcelo Petrucelli, Murillo de Oliveira Goncalves Germano, Anita Popescu, Patrick S. R. Davidson
JOURNAL OF COGNITIVE ENHANCEMENT
(2020)
Article
Linguistics
Cassandra Morrison, Farooq Kamal, Kim Le, Vanessa Taler
BILINGUALISM-LANGUAGE AND COGNITION
(2020)
Article
Linguistics
Cassandra Morrison, Farooq Kamal, Vanessa Taler
BILINGUALISM-LANGUAGE AND COGNITION
(2019)
Article
Geriatrics & Gerontology
Sarah N. Kraeutner, Cristina Rubino, Jennifer K. Ferris, Shie Rinat, Lauren Penko, Larissa Chiu, Brian Greeley, Christina B. Jones, Beverley C. Larssen, Lara A. Boyd
Summary: This study examined the age-related changes in brain function and baseline brain structure that support motor skill acquisition. The findings showed that older adults experienced decreases in functional connectivity during motor skill acquisition, while younger adults experienced increases. Additionally, regardless of age group, lower baseline microstructure in a frontoparietal tract was associated with slower motor skill acquisition.
NEUROBIOLOGY OF AGING
(2024)
Article
Geriatrics & Gerontology
Karen Nuytemans, Farid Rajabli, Melissa Jean-Francois, Jiji Thulaseedhara Kurup, Larry D. Adams, Takiyah D. Starks, Patrice L. Whitehead, Brian W. Kunkle, Allison Caban-Holt, Jonathan L. Haines, Michael L. Cuccaro, Jeffery M. Vance, Goldie S. Byrd, Gary W. Beecham, Christiane Reitz, Margaret A. Pericak-Vance
Summary: This study conducted genetic research on African American AD families and identified a significant linkage signal associated with AD, highlighting the importance of diverse population-level genetic data in understanding the genetic determinants of AD.
NEUROBIOLOGY OF AGING
(2024)
Article
Geriatrics & Gerontology
Kazuya Suwabe, Ryuta Kuwamizu, Kazuki Hyodo, Toru Yoshikawa, Takeshi Otsuki, Asako Zempo-Miyaki, Michael A. Yassa, Hideaki Soya
Summary: Physical exercise has a positive impact on hippocampal memory decline with aging. Recent studies have shown that even light exercise can improve memory and this improvement is mediated by the ascending arousal system. This study aimed to investigate the effects of light-intensity exercise on hippocampal memory function in healthy older adults and found that pupil dilation during exercise played a role in the memory improvement.
NEUROBIOLOGY OF AGING
(2024)
Article
Geriatrics & Gerontology
Ajay Sood, Ana Werneck Capuano, Robert Smith Wilson, Lisa Laverne Barnes, Alifiya Kapasi, David Alan Bennett, Zoe Arvanitakis
Summary: The objective of this study was to explore the impact of metformin on cognition and brain pathology. The results showed that metformin users had slower decline in global cognition, episodic memory, and semantic memory compared to non-users. However, the relationship between metformin use and certain brain pathology remains uncertain.
NEUROBIOLOGY OF AGING
(2024)
Article
Geriatrics & Gerontology
Brian N. Lee, Junwen Wang, Molly A. Hall, Dokyoon Kim, Shana D. Stites, Li Shen
Summary: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by memory and functional impairments. This study analyzed participants from the Alzheimer's Disease Neuroimaging Initiative and found differential associations between cerebral spinal fluid (CSF)/neuroimaging biomarkers and cognitive/functional outcomes, as well as variations between sexes. These findings suggest that sex differences may play a role in the development of AD.
NEUROBIOLOGY OF AGING
(2024)
Article
Geriatrics & Gerontology
Madeline R. Hale, Rebecca Langhough, Lianlian Du, Bruce P. Hermann, Carol A. Van Hulle, Margherita Carboni, Gwendlyn Kollmorgenj, Kristin E. Basche, Davide Bruno, Leah Sanson-Miles, Erin M. Jonaitis, Nathaniel A. Chin, Ozioma C. Okonkwo, Barbara B. Bendlin, Cynthia M. Carlsson, Henrik Zetterberg, Kaj Blennow, Tobey J. Betthauser, Sterling C. Johnson, Kimberly D. Mueller
Summary: This study demonstrates a relationship between cerebrospinal fluid biomarkers and the ability to recall proper names in the preclinical phase of Alzheimer's disease.
NEUROBIOLOGY OF AGING
(2024)
Article
Geriatrics & Gerontology
Thomas T. Austin, Christian L. Thomas, Ben Warren
Summary: This study investigated the effects of age on the robustness and resilience of auditory system using the desert locust. The researchers found that gene expression changes were mainly influenced by age rather than noise exposure. Both young and aged locusts were able to recover their auditory nerve function within 48 hours of noise exposure, but the recovery of transduction current magnitude was impaired in aged locusts. Key genes responsible for robustness to noise exposure in young locusts and potential candidates for compensatory mechanisms in auditory neurons of aged locusts were identified.
NEUROBIOLOGY OF AGING
(2024)