标题
Comparative analysis of assays to measure CAR T-cell-mediated cytotoxicity
作者
关键词
-
出版物
Nature Protocols
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-02-18
DOI
10.1038/s41596-020-00467-0
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- CRISPR-engineered T cells in patients with refractory cancer
- (2020) Edward A. Stadtmauer et al. SCIENCE
- Human chimeric antigen receptor macrophages for cancer immunotherapy
- (2020) Michael Klichinsky et al. NATURE BIOTECHNOLOGY
- Point-Of-Care CAR T-Cell Production (ARI-0001) Using a Closed Semi-automatic Bioreactor: Experience From an Academic Phase I Clinical Trial
- (2020) Maria Castella et al. Frontiers in Immunology
- Automated Manufacture of Autologous CD19 CAR-T Cells for Treatment of Non-hodgkin Lymphoma
- (2020) Zachary Jackson et al. Frontiers in Immunology
- GPRC5D is a target for the immunotherapy of multiple myeloma with rationally designed CAR T cells
- (2019) Eric L. Smith et al. Science Translational Medicine
- Development, application and computational analysis of high-dimensional fluorescent antibody panels for single-cell flow cytometry
- (2019) Jolanda Brummelman et al. Nature Protocols
- Combination Immunotherapy with CAR T Cells and Checkpoint Blockade for the Treatment of Solid Tumors
- (2019) Rachel Grosser et al. CANCER CELL
- A Real-time Potency Assay for Chimeric Antigen Receptor T Cells Targeting Solid and Hematological Cancer Cells
- (2019) Biao Xi et al. Jove-Journal of Visualized Experiments
- Optimizing CAR-T Cell Manufacturing Processes During Pivotal Clinical Trials
- (2019) Seshu Tyagarajan et al. Molecular Therapy-Methods & Clinical Development
- Next generation natural killer cells for cancer immunotherapy: the promise of genetic engineering
- (2018) May Daher et al. CURRENT OPINION IN IMMUNOLOGY
- Driving CARs on the uneven road of antigen heterogeneity in solid tumors
- (2018) Nan Chen et al. CURRENT OPINION IN IMMUNOLOGY
- Regulatory perspective on in vitro potency assays for human T cells used in anti-tumor immunotherapy
- (2018) Charlotte de Wolf et al. CYTOTHERAPY
- Chimeric Antigen Receptor (CAR) T-Cell Therapy for Thoracic Malignancies
- (2018) Stefan Kiesgen et al. Journal of Thoracic Oncology
- In vitro immunotherapy potency assays using real-time cell analysis
- (2018) Fabio Cerignoli et al. PLoS One
- CARs versus BiTEs: A Comparison between T Cell–Redirection Strategies for Cancer Treatment
- (2018) Clare Y. Slaney et al. Cancer Discovery
- Development and characterization of a novel luciferase based cytotoxicity assay
- (2018) Hittu Matta et al. Scientific Reports
- Measuring multiple parameters of CD8+ tumor-infiltrating lymphocytes in human cancers by image analysis
- (2018) Keith E. Steele et al. Journal for ImmunoTherapy of Cancer
- Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency
- (2018) Judith Feucht et al. NATURE MEDICINE
- A real-time digital bio-imaging system to quantify cellular cytotoxicity as an alternative to the standard chromium-51 release assay
- (2017) Julien Fassy et al. IMMUNOLOGY
- A high-performance, non-radioactive potency assay for measuring cytotoxicity: A full substitute of the chromium-release assay targeting the regulatory-compliance objective
- (2017) Alexis Rossignol et al. mAbs
- Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
- (2017) Justin Eyquem et al. NATURE
- Combined immunotherapy with anti-PDL-1/PD-1 and anti-CD4 antibodies cures syngeneic disseminated neuroblastoma
- (2017) Valentina Rigo et al. Scientific Reports
- Immunosuppression in liver tumors: opening the portal to effective immunotherapy
- (2016) P Guha et al. CANCER GENE THERAPY
- Mass Cytometry: Single Cells, Many Features
- (2016) Matthew H. Spitzer et al. CELL
- Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition
- (2016) Leonid Cherkassky et al. JOURNAL OF CLINICAL INVESTIGATION
- The modified FACS calcein AM retention assay: A high throughput flow cytometer based method to measure cytotoxicity
- (2016) M.A. Gillissen et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Optimized T-cell receptor-mimic chimeric antigen receptor T cells directed toward the intracellular Wilms Tumor 1 antigen
- (2016) S Rafiq et al. LEUKEMIA
- A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases
- (2016) Xilin Chen et al. Oncotarget
- A novel method for evaluating antibody-dependent cell-mediated cytotoxicity by flowcytometry using cryopreserved human peripheral blood mononuclear cells
- (2016) Makiko Yamashita et al. Scientific Reports
- Luciferase mRNA Transfection of Antigen Presenting Cells Permits Sensitive Nonradioactive Measurement of Cellular and Humoral Cytotoxicity
- (2016) Tana A. Omokoko et al. Journal of Immunology Research
- Guidelines for the automated evaluation of Elispot assays
- (2015) Sylvia Janetzki et al. Nature Protocols
- Mesothelin-Targeted CARs: Driving T Cells to Solid Tumors
- (2015) A. Morello et al. Cancer Discovery
- CAR-T Cells Inflict Sequential Killing of Multiple Tumor Target Cells
- (2015) Alexander J. Davenport et al. Cancer Immunology Research
- Novel Bispecific Antibodies Increase T-Cell Cytotoxicity against Pancreatic Cancer Cells
- (2014) H.-H. Oberg et al. CANCER RESEARCH
- Chloroquine Inhibits Autophagy to Potentiate Antiestrogen Responsiveness in ER+ Breast Cancer
- (2014) K. L. Cook et al. CLINICAL CANCER RESEARCH
- An impedance-based cytotoxicity assay for real-time and label-free assessment of T-cell-mediated killing of adherent cells
- (2014) Janet Kerstin Peper et al. JOURNAL OF IMMUNOLOGICAL METHODS
- CEA/CD3 bispecific antibody MEDI-565/AMG 211 activation of T cells and subsequent killing of human tumors is independent of mutations commonly found in colorectal adenocarcinomas
- (2014) Michael D Oberst et al. mAbs
- Measuring Cytotoxicity by Bioluminescence Imaging Outperforms the Standard Chromium-51 Release Assay
- (2014) Mobin A. Karimi et al. PLoS One
- Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity
- (2014) P. S. Adusumilli et al. Science Translational Medicine
- xCELLigence system for real-time label-free monitoring of growth and viability of cell lines from hematological malignancies
- (2014) Jordi Martinez-Serra et al. OncoTargets and Therapy
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- Generation of an Adenovirus-Parvovirus Chimera with Enhanced Oncolytic Potential
- (2012) N. El-Andaloussi et al. JOURNAL OF VIROLOGY
- T cells engineered with a T cell receptor against the prostate antigen TARP specifically kill HLA-A2+ prostate and breast cancer cells
- (2012) V. Hillerdal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ELISPOT Assay for Monitoring Cytotoxic T Lymphocytes (CTL) Activity in Cancer Vaccine Clinical Trials
- (2012) Anatoli M. Malyguine et al. Cells
- Illuminating Insights into Firefly Luciferase and Other Bioluminescent Reporters Used in Chemical Biology
- (2010) Natasha Thorne et al. CHEMISTRY & BIOLOGY
- Enhancement of NK cell antitumor responses using an oncolytic parvovirus
- (2010) Rauf Bhat et al. INTERNATIONAL JOURNAL OF CANCER
- A Simple and Sensitive Method for Measuring Tumor-Specific T Cell Cytotoxicity
- (2010) Xinping Fu et al. PLoS One
- Breast tumor cells isolated from in vitro resistance to trastuzumab remain sensitive to trastuzumab anti-tumor effects in vivo and to ADCC killing
- (2009) Timothy E. Kute et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- The role of IFN-γ Elispot assay in HIV vaccine research
- (2009) Hendrik Streeck et al. Nature Protocols
- Expression, purification and use of recombinant annexin V for the detection of apoptotic cells
- (2009) Susan E Logue et al. Nature Protocols
- The PtdIns 3-Kinase/Akt Pathway Regulates Macrophage-Mediated ADCC against B Cell Lymphoma
- (2009) Trupti Joshi et al. PLoS One
- Thrombospondin 1 Promotes Tumor Macrophage Recruitment and Enhances Tumor Cell Cytotoxicity of Differentiated U937 Cells
- (2008) G. Martin-Manso et al. CANCER RESEARCH
- Intracellular protease activation in apoptosis and cell-mediated cytotoxicity characterized by cell-permeable fluorogenic protease substrates
- (2008) Beverly Z Packard et al. CELL RESEARCH
- Relationship between CD107a expression and cytotoxic activity
- (2008) Esin Aktas et al. CELLULAR IMMUNOLOGY
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