A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity
出版年份 2021 全文链接
标题
A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity
作者
关键词
-
出版物
NATURE MEDICINE
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-02-25
DOI
10.1038/s41591-021-01281-1
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A genomic region associated with protection against severe COVID-19 is inherited from Neandertals
- (2021) Hugo Zeberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic
- (2020) EUROPEAN JOURNAL OF HUMAN GENETICS
- Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report
- (2020) NEW ENGLAND JOURNAL OF MEDICINE
- Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19
- (2020) et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- The major genetic risk factor for severe COVID-19 is inherited from Neanderthals
- (2020) Hugo Zeberg et al. NATURE
- Genetic mechanisms of critical illness in Covid-19
- (2020) Erola Pairo-Castineira et al. NATURE
- Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results
- (2020) NEW ENGLAND JOURNAL OF MEDICINE
- Genetic architecture of host proteins involved in SARS-CoV-2 infection
- (2020) Maik Pietzner et al. Nature Communications
- Recurrent Loss-of-Function Mutations Reveal Costs to OAS1 Antiviral Activity in Primates
- (2019) Clayton M. Carey et al. Cell Host & Microbe
- The MR-Base platform supports systematic causal inference across the human phenome
- (2018) Gibran Hemani et al. eLife
- Genomic atlas of the human plasma proteome
- (2018) Benjamin B. Sun et al. NATURE
- Co-regulatory networks of human serum proteins link genetics to disease
- (2018) Valur Emilsson et al. SCIENCE
- Genome‐wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease
- (2018) Chen Yao et al. Nature Communications
- Genetic effects on gene expression across human tissues
- (2017) François Aguet et al. NATURE
- A high-coverage Neandertal genome from Vindija Cave in Croatia
- (2017) Kay Prüfer et al. SCIENCE
- Connecting genetic risk to disease end points through the human blood plasma proteome
- (2017) Karsten Suhre et al. Nature Communications
- Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons
- (2017) He Li et al. PLoS Genetics
- Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease
- (2017) Lasse Folkersen et al. PLoS Genetics
- PhenoScanner: a database of human genotype–phenotype associations
- (2016) James R. Staley et al. BIOINFORMATICS
- Bias due to participant overlap in two-sample Mendelian randomization
- (2016) Stephen Burgess et al. GENETIC EPIDEMIOLOGY
- Cellular responses to HSV-1 infection are linked to specific types of alterations in the host transcriptome
- (2016) Benxia Hu et al. Scientific Reports
- A robust type I interferon gene signature from blood RNA defines quantitative but not qualitative differences between three major IFN drugs in the treatment of multiple sclerosis
- (2015) D. Harari et al. HUMAN MOLECULAR GENETICS
- The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors
- (2015) Edgar R. Wood et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- High Anti–Dengue Virus Activity of theOASGene Family Is Associated With Increased Severity of Dengue
- (2015) Etienne Simon-Loriere et al. JOURNAL OF INFECTIOUS DISEASES
- A global reference for human genetic variation
- (2015) Richard A. Gibbs et al. NATURE
- The support of human genetic evidence for approved drug indications
- (2015) Matthew R Nelson et al. NATURE GENETICS
- Second-generation PLINK: rising to the challenge of larger and richer datasets
- (2015) Christopher C Chang et al. GigaScience
- Interferon-Stimulated Genes: A Complex Web of Host Defenses
- (2014) William M. Schneider et al. Annual Review of Immunology
- Interferons: Success in anti-viral immunotherapy
- (2014) Fan-ching Lin et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Viral Phosphodiesterases That Antagonize Double-Stranded RNA Signaling to RNase L by Degrading 2-5A
- (2014) Robert H. Silverman et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework
- (2014) David Cook et al. NATURE REVIEWS DRUG DISCOVERY
- Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
- (2014) Claudia Giambartolomei et al. PLoS Genetics
- Neandertal Origin of Genetic Variation at the Cluster of OAS Immunity Genes
- (2013) F. L. Mendez et al. MOLECULAR BIOLOGY AND EVOLUTION
- Homologous 2',5'-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity
- (2013) R. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Antagonism of the Interferon-Induced OAS-RNase L Pathway by Murine Coronavirus ns2 Protein Is Required for Virus Replication and Liver Pathology
- (2012) Ling Zhao et al. Cell Host & Microbe
- A High-Coverage Genome Sequence from an Archaic Denisovan Individual
- (2012) M. Meyer et al. SCIENCE
- Pharmacologic Activation of the Innate Immune System to Prevent Respiratory Viral Infections
- (2010) Guanjun Cheng et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Extracellular 2'-5' Oligoadenylate Synthetase Stimulates RNase L-Independent Antiviral Activity: a Novel Mechanism of Virus-Induced Innate Immunity
- (2010) H. Kristiansen et al. JOURNAL OF VIROLOGY
- Genetic Variation in OAS1 Is a Risk Factor for Initial Infection with West Nile Virus in Man
- (2009) Jean K. Lim et al. PLoS Pathogens
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started