Targeting eosinophils in respiratory diseases: Biological axis, emerging therapeutics and treatment modalities
出版年份 2021 全文链接
标题
Targeting eosinophils in respiratory diseases: Biological axis, emerging therapeutics and treatment modalities
作者
关键词
-
出版物
LIFE SCIENCES
Volume 267, Issue -, Pages 118973
出版商
Elsevier BV
发表日期
2021-01-02
DOI
10.1016/j.lfs.2020.118973
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Eosinophils in chronic obstructive pulmonary disease
- (2020) Christine F. McDonald CURRENT OPINION IN PULMONARY MEDICINE
- Targeting neutrophils using novel drug delivery systems in chronic respiratory diseases
- (2020) Dinesh K. Chellappan et al. DRUG DEVELOPMENT RESEARCH
- Use of mepolizumab in adult patients with cystic fibrosis and an eosinophilic phenotype: case series
- (2020) Lijia Zhang et al. Allergy Asthma and Clinical Immunology
- Celastrol-loaded liquid crystalline nanoparticles as an anti-inflammatory intervention for the treatment of asthma
- (2020) Yinghan Chan et al. International Journal of Polymeric Materials and Polymeric Biomaterials
- Cellular signalling pathways mediating the pathogenesis of chronic inflammatory respiratory diseases: an update
- (2020) Meenu Mehta et al. INFLAMMOPHARMACOLOGY
- A Sputum 6 Gene Expression Signature Predicts Inflammatory Phenotypes and Future Exacerbations of COPD
- (2020) Katherine J Baines et al. International Journal of Chronic Obstructive Pulmonary Disease
- Chronic eosinophilic pneumonia: clinical perspectives
- (2019) Matthew Crowe et al. Therapeutics and Clinical Risk Management
- Identification of biomarkers and genetic approaches toward chronic obstructive pulmonary disease
- (2019) Ridhima Wadhwa et al. JOURNAL OF CELLULAR PHYSIOLOGY
- A sputum 6-gene signature predicts future exacerbations of poorly controlled asthma
- (2019) Michael Fricker et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Interactions with the macrophages: An emerging targeted approach using novel drug delivery systems in respiratory diseases
- (2019) Meenu Mehta et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases
- (2019) Meenu Mehta et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Stability of the Blood Eosinophilic Phenotype in Stable and Exacerbated COPD
- (2019) Desiree M. Schumann et al. CHEST
- Blood Eosinophil Counts, Withdrawal of Inhaled Corticosteroids and Risk of COPD Exacerbations and Mortality in the Clinical Practice Research Datalink (CPRD)
- (2019) Olorunfemi A. Oshagbemi et al. COPD-Journal of Chronic Obstructive Pulmonary Disease
- Synergy of Interleukin (IL)-5 and IL-18 in eosinophil mediated pathogenesis of allergic diseases
- (2019) Hemanth Kumar Kandikattu et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Hypereosinophilia in a patient with metastatic non-small-cell lung cancer treated with antiprogrammed cell death 1 (anti-PD-1) therapy
- (2019) Yanyan Lou et al. Immunotherapy
- Benralizumab: A New Approach for the Treatment of Severe Eosinophilic Asthma
- (2019) I Dávila González et al. JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
- Benralizumab for the Prevention of COPD Exacerbations
- (2019) Gerard J. Criner et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting bacterial biofilms in pulmonary diseases in pediatric population
- (2019) Kamal Dua et al. MINERVA PEDIATRICA
- Review of Drug Development Guidance to Treat Chronic Obstructive Pulmonary Disease: US and EU Perspectives
- (2019) Aernout Haarst et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- The potential of siRNA based drug delivery in respiratory disorders: Recent advances and progress
- (2019) Kamal Dua et al. DRUG DEVELOPMENT RESEARCH
- Blood eosinophils as biomarkers of therapeutic response to chronic obstructive pulmonary disease: Still work in progress
- (2019) Salvatore Fuschillo et al. European Journal of Internal Medicine
- Association between peripheral blood markers and immune-related factors on tumor cells in patients with resected primary lung adenocarcinoma
- (2019) Kazuki Takada et al. PLoS One
- Eosinophilic pneumonia: A review of the previous literature, causes, diagnosis, and management
- (2019) Yuzo Suzuki et al. ALLERGOLOGY INTERNATIONAL
- Eosinophil Inflammation and Hyperresponsiveness in the Airways as Phenotypes of COPD, and Usefulness of Inhaled Glucocorticosteroids
- (2019) Hiroaki Kume et al. Frontiers in Pharmacology
- Sputum Streptococcus pneumoniae is reduced in COPD following treatment with benralizumab
- (2019) Leena George et al. International Journal of Chronic Obstructive Pulmonary Disease
- Blood eosinophils and treatment response with triple and dual combination therapy in chronic obstructive pulmonary disease: analysis of the IMPACT trial
- (2019) Steven Pascoe et al. Lancet Respiratory Medicine
- Epidemiology of Asthma in Children and Adults
- (2019) Shyamali C. Dharmage et al. Frontiers in Pediatrics
- Reassessing the Role of Eosinophils as a Biomarker in Chronic Obstructive Pulmonary Disease
- (2019) Tinè et al. Journal of Clinical Medicine
- Emerging trends in the novel drug delivery approaches for the treatment of lung cancer
- (2019) Parvarish Sharma et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Interactions between microbiome and lungs: Paving new paths for microbiome based bio-engineered drug delivery systems in chronic respiratory diseases
- (2019) Dinesh Kumar Chellappan et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Blood eosinophil count as a predictor of hospital length of stay in COPD exacerbations
- (2019) Fanny W.S. Ko et al. RESPIROLOGY
- Severe Eosinophilic Asthma
- (2019) Bakakos et al. Journal of Clinical Medicine
- Dupilumab: A Review in Moderate to Severe Asthma
- (2019) Emma D. Deeks DRUGS
- Association of plasma fibrinogen concentrations and blood eosinophil counts with clinical phenotypes of COPD
- (2019) D-G. Hyun et al. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
- Eosinophils, the IL-5/IL-5Rα axis, and the biologic effects of benralizumab in severe asthma
- (2019) Andrea Matucci et al. RESPIRATORY MEDICINE
- Cystic Fibrosis: Pathophysiology of Lung Disease
- (2019) Christelle Bergeron et al. SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE
- Preparation, characterization and in-vitro efficacy of quercetin loaded liquid crystalline nanoparticles for the treatment of asthma
- (2019) David Ong Cherk Yong et al. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
- Single and Synergistic Effects of Type 2 Cytokines on Eosinophils and Asthma Hallmarks
- (2019) Hendrik Beckert et al. JOURNAL OF IMMUNOLOGY
- Immunological biomarkers in severe asthma
- (2019) Dharani Narendra et al. SEMINARS IN IMMUNOLOGY
- Long-term Triple Therapy De-escalation to Indacaterol/Glycopyrronium in COPD Patients (SUNSET): a Randomized, Double-Blind, Triple-Dummy Clinical Trial
- (2018) Kenneth R Chapman et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Eosinophilic and Noneosinophilic Asthma
- (2018) Tara F. Carr et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Acute Eosinophilic Pneumonia. Causes, Diagnosis, and Management
- (2018) Federica De Giacomi et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Benralizumab efficacy by atopy status and serum immunoglobulin E for patients with severe, uncontrolled asthma
- (2018) Bradley E. Chipps et al. ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
- Blood biomarkers as predictors of long-term mortality in COPD
- (2018) Angelico Mendy et al. Clinical Respiratory Journal
- Reduction of respiratory infections in asthma patients supplemented with vitamin D is related to increased serum IL-10 and IFNγ levels and cathelicidin expression
- (2018) E. Ramos-Martínez et al. CYTOKINE
- Biological therapies for eosinophilic asthma
- (2018) Shiven S. Patel et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Immunological axis of curcumin-loaded vesicular drug delivery systems
- (2018) Dinesh K Chellappan et al. Future Medicinal Chemistry
- Sputum transcriptomics reveal upregulation of IL-1 receptor family members in patients with severe asthma
- (2018) Christos Rossios et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Prospective Open-Label Study of 48-Week Subcutaneous Administration of Mepolizumab in Japanese Patients with Severe Eosinophilic Asthma
- (2018) M Kurosawa et al. JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
- Inflammation in cystic fibrosis: An update
- (2018) Erica A. Roesch et al. PEDIATRIC PULMONOLOGY
- Inhaled nebulised unfractionated heparin improves lung function in moderate to very severe COPD: A pilot study
- (2018) Janis K. Shute et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- Tailoring asthma treatment on eosinophilic markers (exhaled nitric oxide or sputum eosinophils): a systematic review and meta-analysis
- (2018) Helen L Petsky et al. THORAX
- Update on new biologics for intractable eosinophilic asthma: impact of reslizumab
- (2018) Jagdeep Sahota et al. Drug Design Development and Therapy
- Role of eosinophils in airway inflammation of chronic obstructive pulmonary disease
- (2018) Donald P Tashkin et al. International Journal of Chronic Obstructive Pulmonary Disease
- Predictors of exacerbation risk and response to budesonide in patients with chronic obstructive pulmonary disease: a post-hoc analysis of three randomised trials
- (2018) Mona Bafadhel et al. Lancet Respiratory Medicine
- Tiotropium Respimat Add-on Is Efficacious in Symptomatic Asthma, Independent of T2 Phenotype
- (2018) Thomas B. Casale et al. Journal of Allergy and Clinical Immunology-In Practice
- Asthma Exacerbations Associated with Lung Function Decline in Patients with Severe Eosinophilic Asthma
- (2018) Hector Ortega et al. Journal of Allergy and Clinical Immunology-In Practice
- Assessing the potential of liposomes loaded with curcumin as a therapeutic intervention in asthma
- (2018) Zhao Yin Ng et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- Neutrophilic Inflammation in the Pathogenesis of Chronic Obstructive Pulmonary Disease
- (2018) Aidan Butler et al. COPD-Journal of Chronic Obstructive Pulmonary Disease
- Poor Relationship Between Fractionated Exhaled Nitric Oxide and Disease Activity in Eosinophilic Esophagitis
- (2018) Kimberly Johnson et al. DYSPHAGIA
- Baseline Patient Factor Impact on the Clinical Efficacy of Benralizumab for Severe Asthma
- (2018) Eugene R. Bleecker et al. EUROPEAN RESPIRATORY JOURNAL
- Inhaled corticosteroid containing combinations and mortality in COPD
- (2018) Jørgen Vestbo et al. EUROPEAN RESPIRATORY JOURNAL
- Eosinophil-derived neurotoxin enhances airway remodeling in eosinophilic chronic rhinosinusitis and correlates with disease severity
- (2018) Takeshi Tsuda et al. INTERNATIONAL IMMUNOLOGY
- Anti–IL-5 treatments in patients with severe asthma by blood eosinophil thresholds: Indirect treatment comparison
- (2018) William Busse et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Eosinophil recruitment is dynamically regulated by interplay among lung dendritic cell subsets after allergen challenge
- (2018) Shuying Yi et al. Nature Communications
- Eosinophil counts in first COPD hospitalizations: a comparison of health service utilization
- (2018) Maryse Bélanger et al. International Journal of Chronic Obstructive Pulmonary Disease
- Anti-inflammatory effects of roflumilast in chronic obstructive pulmonary disease (ROBERT): a 16-week, randomised, placebo-controlled trial
- (2018) Klaus F Rabe et al. Lancet Respiratory Medicine
- Reslizumab Compared with Benralizumab in Patients with Eosinophilic Asthma: A Systematic Literature Review and Network Meta-Analysis
- (2018) Thomas B. Casale et al. Journal of Allergy and Clinical Immunology-In Practice
- Cystic Fibrosis: Emerging Understanding and Therapies
- (2018) Michael M. Rey et al. Annual Review of Medicine
- RPC4046, a Monoclonal Antibody Against IL13, Reduces Histologic and Endoscopic Activity in Patients With Eosinophilic Esophagitis
- (2018) Ikuo Hirano et al. GASTROENTEROLOGY
- The Effect of Helminths on Granulocyte Activation: A Cluster-Randomized Placebo-Controlled Trial in Indonesia
- (2018) Karin de Ruiter et al. JOURNAL OF INFECTIOUS DISEASES
- Eosinophils: Old Players in a New Game
- (2018) B Sastre et al. JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY
- Nasal Discharge Eosinophils in Childhood Asthma Patients as a Predictive Factor for Persistent Asthma
- (2018) Norihide Murayama et al. MEDIATORS OF INFLAMMATION
- Impact of an increase in the inhaled corticosteroid dose on blood eosinophils in asthma
- (2018) Marek Lommatzsch et al. THORAX
- Eosinophils Target Therapy for Severe Asthma: Critical Points
- (2018) L. Brussino et al. Biomed Research International
- Blood eosinophil count as a prognostic biomarker in COPD
- (2018) Yeon-Mok Oh et al. International Journal of Chronic Obstructive Pulmonary Disease
- Comparative effectiveness of LABA-ICS versus LAMA as initial treatment in COPD targeted by blood eosinophils: a population-based cohort study
- (2018) Samy Suissa et al. Lancet Respiratory Medicine
- Increasing complexity and interactions of oxidative stress in chronic respiratory diseases: An emerging need for novel drug delivery systems
- (2018) Kamal Dua et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Impact and associations of eosinophilic inflammation in COPD: analysis of the AERIS cohort
- (2017) Viktoriya L. Kim et al. EUROPEAN RESPIRATORY JOURNAL
- Long-term effects of inhaled corticosteroids on sputum bacterial and viral loads in COPD
- (2017) Marco Contoli et al. EUROPEAN RESPIRATORY JOURNAL
- Eosinophilic airway inflammation in asthmatic patients is associated with an altered airway microbiome
- (2017) Asger Sverrild et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Group 2 innate lymphoid cells are recruited to the nasal mucosa in patients with aspirin-exacerbated respiratory disease
- (2017) Jacqueline J. Eastman et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- A randomized multicenter study evaluating Xolair persistence of response after long-term therapy
- (2017) Dennis Ledford et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Reduced need for surgery in severe nasal polyposis with mepolizumab: Randomized trial
- (2017) Claus Bachert et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Effect of obesity on sinonasal disease in asthma
- (2017) S. Kanagalingam et al. JOURNAL OF ASTHMA
- Single inhaler extrafine triple therapy versus long-acting muscarinic antagonist therapy for chronic obstructive pulmonary disease (TRINITY): a double-blind, parallel group, randomised controlled trial
- (2017) Jørgen Vestbo et al. LANCET
- Possible Role of IL-25 in Eosinophilic Lung Inflammation in Patients with Chronic Eosinophilic Pneumonia
- (2017) Shigeki Katoh et al. LUNG
- Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease
- (2017) Ian D. Pavord et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mepolizumab or Placebo for Eosinophilic Granulomatosis with Polyangiitis
- (2017) Michael E. Wechsler et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nigella sativaSupplementation Improves Asthma Control and Biomarkers: A Randomized, Double-Blind, Placebo-Controlled Trial
- (2017) Abdulrahman Koshak et al. PHYTOTHERAPY RESEARCH
- Withdrawal of inhaled corticosteroids in COPD: A meta-analysis
- (2017) Luigino Calzetta et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- Biological effects of p38 MAPK inhibitor losmapimod does not translate to clinical benefits in COPD
- (2017) Steven Pascoe et al. RESPIRATORY MEDICINE
- A multi-center randomized, controlled, open-label trial evaluating the effects of eosinophil-guided corticosteroid-sparing therapy in hospitalised patients with COPD exacerbations – The CORTICO steroid reduction in COPD (CORTICO-COP) study protocol
- (2017) Pradeesh Sivapalan et al. BMC Pulmonary Medicine
- Efficacy and safety of mepolizumab in Japanese patients with severe eosinophilic asthma
- (2017) Terufumi Shimoda et al. ALLERGOLOGY INTERNATIONAL
- Relationship between blood eosinophils, clinical characteristics, and mortality in patients with COPD
- (2017) maeva zysman et al. International Journal of Chronic Obstructive Pulmonary Disease
- Emerging pharmaceutical therapies for COPD
- (2017) Sowmya Lakshmi et al. International Journal of Chronic Obstructive Pulmonary Disease
- Fluticasone propionate/formoterol for COPD management: a randomized controlled trial
- (2017) A Papi et al. International Journal of Chronic Obstructive Pulmonary Disease
- Eosinophils in COPD: just another biomarker?
- (2017) Mona Bafadhel et al. Lancet Respiratory Medicine
- Benralizumab for patients with mild to moderate, persistent asthma (BISE): a randomised, double-blind, placebo-controlled, phase 3 trial
- (2017) Gary T Ferguson et al. Lancet Respiratory Medicine
- Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort
- (2017) Annette T Hastie et al. Lancet Respiratory Medicine
- Efficacy of mepolizumab add-on therapy on health-related quality of life and markers of asthma control in severe eosinophilic asthma (MUSCA): a randomised, double-blind, placebo-controlled, parallel-group, multicentre, phase 3b trial
- (2017) Geoffrey L Chupp et al. Lancet Respiratory Medicine
- Plasma 15-Hydroxyeicosatetraenoic Acid Predicts Treatment Outcomes in Aspirin-Exacerbated Respiratory Disease
- (2017) Elina Jerschow et al. Journal of Allergy and Clinical Immunology-In Practice
- Eosinophils: The unsung heroes in cancer?
- (2017) Gilda Varricchi et al. OncoImmunology
- Exhaled Nitric Oxide is Related to Bronchial Eosinophilia and Airway Hyperresponsiveness to Bradykinin in Allergen-Induced Asthma Exacerbation
- (2017) F.L.M. Ricciardolo et al. INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY
- Blood Eosinophils and Exacerbations in Chronic Obstructive Pulmonary Disease. The Copenhagen General Population Study
- (2016) Signe Vedel-Krogh et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Role of local eosinophilopoietic processes in the development of airway eosinophilia in prednisone-dependent severe asthma
- (2016) R. Sehmi et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Exacerbation risk in severe asthma is stratified by inflammatory phenotype using longitudinal measures of sputum eosinophils
- (2016) C. J. Walsh et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Long-term Efficacy and Safety of Mepolizumab in Patients With Severe Eosinophilic Asthma: A Multi-center, Open-label, Phase IIIb Study
- (2016) Njira Lugogo et al. CLINICAL THERAPEUTICS
- Eosinophilic Lung Diseases
- (2016) Vincent Cottin CLINICS IN CHEST MEDICINE
- Interleukin-5 pathway inhibition in the treatment of eosinophilic respiratory disorders
- (2016) Gilda Varricchi et al. Current Opinion in Allergy and Clinical Immunology
- Blood eosinophils as a marker of response to inhaled corticosteroids in COPD
- (2016) Neil C. Barnes et al. EUROPEAN RESPIRATORY JOURNAL
- A Phase 2a Study of Benralizumab for Patients with Eosinophilic Asthma in South Korea and Japan
- (2016) Hae-Sim Park et al. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
- Individualized therapy for persistent asthma in young children
- (2016) Anne M. Fitzpatrick et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- CD63 is tightly associated with intracellular, secretory events chaperoning piecemeal degranulation and compound exocytosis in human eosinophils
- (2016) Lívia A. S. Carmo et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial
- (2016) Sally Wenzel et al. LANCET
- Fluticasone furoate and vilanterol and survival in chronic obstructive pulmonary disease with heightened cardiovascular risk (SUMMIT): a double-blind randomised controlled trial
- (2016) Jørgen Vestbo et al. LANCET
- Indacaterol–Glycopyrronium versus Salmeterol–Fluticasone for COPD
- (2016) Jadwiga A. Wedzicha et al. NEW ENGLAND JOURNAL OF MEDICINE
- Relationship between blood eosinophils and clinical characteristics in a cross-sectional study of a US population-based COPD cohort
- (2016) Rachael L. DiSantostefano et al. RESPIRATORY MEDICINE
- Assessing biomarkers in a real-world severe asthma study (ARIETTA)
- (2016) Roland Buhl et al. RESPIRATORY MEDICINE
- A 12-year prognosis of adult-onset asthma: Seinäjoki Adult Asthma Study
- (2016) Leena E. Tuomisto et al. RESPIRATORY MEDICINE
- Predictors of frequent exacerbations in (ex)smoking and never smoking adults with severe asthma
- (2016) Guus A. Westerhof et al. RESPIRATORY MEDICINE
- Periostin levels and eosinophilic inflammation in poorly-controlled asthma
- (2016) Jodie L. Simpson et al. BMC Pulmonary Medicine
- Identification of responders to inhaled corticosteroids in a chronic obstructive pulmonary disease population using cluster analysis
- (2016) David R Hinds et al. BMJ Open
- Effectiveness using higher inhaled corticosteroid dosage in patients with COPD by different blood eosinophilic counts
- (2016) Shih-Lung Cheng et al. International Journal of Chronic Obstructive Pulmonary Disease
- Peripheral blood eosinophils: a surrogate marker for airway eosinophilia in stable COPD
- (2016) Netsanet Negewo et al. International Journal of Chronic Obstructive Pulmonary Disease
- Fevipiprant, a prostaglandin D 2 receptor 2 antagonist, in patients with persistent eosinophilic asthma: a single-centre, randomised, double-blind, parallel-group, placebo-controlled trial
- (2016) Sherif Gonem et al. Lancet Respiratory Medicine
- Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids: a post-hoc analysis of the WISDOM trial
- (2016) Henrik Watz et al. Lancet Respiratory Medicine
- Efficacy and safety of lebrikizumab in patients with uncontrolled asthma (LAVOLTA I and LAVOLTA II): replicate, phase 3, randomised, double-blind, placebo-controlled trials
- (2016) Nicola A Hanania et al. Lancet Respiratory Medicine
- Severe eosinophilic asthma treated with mepolizumab stratified by baseline eosinophil thresholds: a secondary analysis of the DREAM and MENSA studies
- (2016) Hector G Ortega et al. Lancet Respiratory Medicine
- Mepolizumab in the management of severe eosinophilic asthma in adults: current evidence and practical experience
- (2016) Gilda Varricchi et al. Therapeutic Advances in Respiratory Disease
- A randomized trial of benralizumab, an antiinterleukin 5 receptor α monoclonal antibody, after acute asthma
- (2015) Richard M. Nowak et al. AMERICAN JOURNAL OF EMERGENCY MEDICINE
- Blood Eosinophils: A Biomarker of Response to Extrafine Beclomethasone/Formoterol in Chronic Obstructive Pulmonary Disease
- (2015) Salman H. Siddiqui et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Determinants of eosinophil survival and apoptotic cell death
- (2015) Zhong-Jian Shen et al. APOPTOSIS
- Biomarker Profiles in Asthma With High vs Low Airway Reversibility and Poor Disease Control
- (2015) William W. Busse et al. CHEST
- The Eosinophil in Health and Disease: from Bench to Bedside and Back
- (2015) Wei Liao et al. CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
- The Eosinophil in Infection
- (2015) Karen A. Ravin et al. CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
- Efficacy of short-term prednisolone treatment in patients with chronic eosinophilic pneumonia
- (2015) Yoshiyuki Oyama et al. EUROPEAN RESPIRATORY JOURNAL
- Biomarkers to identify sputum eosinophilia in different adult asthma phenotypes
- (2015) Guus A. Westerhof et al. EUROPEAN RESPIRATORY JOURNAL
- Uncovering a new role for peroxidase enzymes as drivers of angiogenesis
- (2015) Vasilios Panagopoulos et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Eosinophils orchestrate cancer rejection by normalizing tumor vessels and enhancing infiltration of CD8+ T cells
- (2015) Rafael Carretero et al. NATURE IMMUNOLOGY
- A post-hoc subgroup analysis of data from a six month clinical trial comparing the efficacy and safety of losmapimod in moderate-severe COPD patients with ≤2% and >2% blood eosinophils
- (2015) Joanna Marks-Konczalik et al. RESPIRATORY MEDICINE
- Type 2 innate lymphoid cells: A novel biomarker of eosinophilic airway inflammation in patients with mild to moderate asthma
- (2015) Tian Liu et al. RESPIRATORY MEDICINE
- Blood eosinophils and inhaled corticosteroid/long-acting β-2 agonist efficacy in COPD
- (2015) Ian D Pavord et al. THORAX
- Pathogenic Th2 (Tpath2) cells in airway inflammation
- (2015) Yusuke Endo et al. Oncotarget
- Blood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease: a secondary analysis of data from two parallel randomised controlled trials
- (2015) Steven Pascoe et al. Lancet Respiratory Medicine
- Reslizumab for inadequately controlled asthma with elevated blood eosinophil counts: results from two multicentre, parallel, double-blind, randomised, placebo-controlled, phase 3 trials
- (2015) Mario Castro et al. Lancet Respiratory Medicine
- Blood eosinophil count and prospective annual asthma disease burden: a UK cohort study
- (2015) David B Price et al. Lancet Respiratory Medicine
- Efficacy and safety of reslizumab in patients with moderate to severe eosinophilic asthma
- (2015) Hui Fang Lim et al. Expert Review of Respiratory Medicine
- Chronic obstructive pulmonary disease
- (2015) Peter J. Barnes et al. Nature Reviews Disease Primers
- Eosinophilic airway inflammation: role in asthma and chronic obstructive pulmonary disease
- (2015) Leena George et al. Therapeutic Advances in Chronic Disease
- Stability of phenotypes defined by physiological variables and biomarkers in adults with asthma
- (2014) M. Kupczyk et al. ALLERGY
- Heightened response of eosinophilic asthmatic patients to the CRTH2 antagonist OC000459
- (2014) R. Pettipher et al. ALLERGY
- Objective allergy markers and risk of cancer mortality and hospitalization in a large population-based cohort
- (2014) Niloofar Taghizadeh et al. CANCER CAUSES & CONTROL
- Activation states of blood eosinophils in asthma
- (2014) M. W. Johansson CLINICAL AND EXPERIMENTAL ALLERGY
- The effects of an epithelial barrier protective cationic aerosol on allergen-induced airway inflammation in asthma: a randomized, placebo-controlled clinical trial
- (2014) P. Nair et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Eosinophilic inflammation in COPD: prevalence and clinical characteristics: Table 1–
- (2014) Dave Singh et al. EUROPEAN RESPIRATORY JOURNAL
- Effects of regular treatment with combination of salmeterol/fluticasone propionate and salmeterol alone in cough variant asthma
- (2014) Etsuko Tagaya et al. JOURNAL OF ASTHMA
- Eosinophil Granule Proteins: Form and Function
- (2014) K. Ravi Acharya et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Eosinophils Regulate Peripheral B Cell Numbers in Both Mice and Humans
- (2014) T. W. Wong et al. JOURNAL OF IMMUNOLOGY
- Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma
- (2014) Hector G. Ortega et al. NEW ENGLAND JOURNAL OF MEDICINE
- Biological effects of leukotriene E4 on eosinophils
- (2014) John W. Steinke et al. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- External validation of blood eosinophils, FENOand serum periostin as surrogates for sputum eosinophils in asthma
- (2014) A H Wagener et al. THORAX
- COPD exacerbation severity and frequency is associated with impaired macrophage efferocytosis of eosinophils
- (2014) Osama Eltboli et al. BMC Pulmonary Medicine
- Eosinophils and Cancer
- (2014) B. P. Davis et al. Cancer Immunology Research
- Benralizumab for chronic obstructive pulmonary disease and sputum eosinophilia: a randomised, double-blind, placebo-controlled, phase 2a study
- (2014) Christopher E Brightling et al. Lancet Respiratory Medicine
- Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study
- (2014) Mario Castro et al. Lancet Respiratory Medicine
- Eosinophil Cytokines, Chemokines, and Growth Factors: Emerging Roles in Immunity
- (2014) Francis Davoine et al. Frontiers in Immunology
- Eosinophil Secretion of Granule-Derived Cytokines
- (2014) Lisa A. Spencer et al. Frontiers in Immunology
- A Th17- and Th2-skewed Cytokine Profile in Cystic Fibrosis Lungs Represents a Potential Risk Factor forPseudomonas aeruginosaInfection
- (2013) Kerstin Tiringer et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Elevated Sputum Interleukin-5 and Submucosal Eosinophilia in Obese Individuals with Severe Asthma
- (2013) Dhananjay Desai et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Exploring the Effects of Omalizumab in Allergic Asthma
- (2013) Nicola A. Hanania et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Interaction between allergy and innate immunity: model for eosinophil regulation of epithelial cell interferon expression
- (2013) Sameer K. Mathur et al. ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
- Eosinophil activation and novel mediators in the aspirin-induced nasal response in AERD
- (2013) G.-S. Choi et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Differential Activation of Eosinophils by Bacteria Associated with Asthma
- (2013) Koa Hosoki et al. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
- Biomarker surrogates do not accurately predict sputum eosinophil and neutrophil percentages in asthmatic subjects
- (2013) Annette T. Hastie et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Targeting eosinophils in allergy, inflammation and beyond
- (2013) Patricia C. Fulkerson et al. NATURE REVIEWS DRUG DISCOVERY
- Phenotypic predictors of response to oral glucocorticosteroids in severe asthma
- (2013) Maciej Kupczyk et al. RESPIRATORY MEDICINE
- Impact of Bacillus Calmette–Guérin Moreau vaccine on lung remodeling in experimental asthma
- (2013) Cynthia dos Santos Samary et al. RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
- Azithromycin for prevention of exacerbations in severe asthma (AZISAST): a multicentre randomised double-blind placebo-controlled trial
- (2013) Guy G Brusselle et al. THORAX
- Airway inflammation in cystic fibrosis: molecular mechanisms and clinical implications
- (2013) Malena Cohen-Cymberknoh et al. THORAX
- Biodistribution of the GATA-3-specific DNAzyme hgd40 after inhalative exposure in mice, rats and dogs
- (2013) Agnieszka Turowska et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Pathophysiology of cystic fibrosis and drugs used in associated digestive tract diseases
- (2013) Adriana Haack WORLD JOURNAL OF GASTROENTEROLOGY
- Blood Eosinophils to Direct Corticosteroid Treatment of Exacerbations of Chronic Obstructive Pulmonary Disease
- (2012) Mona Bafadhel et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- A Large Subgroup of Mild-to-Moderate Asthma Is Persistently Noneosinophilic
- (2012) Kelly Wong McGrath et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
- (2012) Jørgen Vestbo et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Eosinophilic Pneumonias
- (2012) P. Akuthota et al. CLINICAL MICROBIOLOGY REVIEWS
- Pattern-recognition receptors in human eosinophils
- (2012) Anne Månsson Kvarnhammar et al. IMMUNOLOGY
- Asthma outcomes: Biomarkers
- (2012) Stanley J. Szefler et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients
- (2012) Guiquan Jia et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Eosinophils Induce Airway Smooth Muscle Cell Proliferation
- (2012) Rabih Halwani et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Eosinophil crystalloid granules: structure, function, and beyond
- (2012) Valdirene S. Muniz et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Siglec-8 as a drugable target to treat eosinophil and mast cell-associated conditions
- (2012) Takumi Kiwamoto et al. PHARMACOLOGY & THERAPEUTICS
- Galectin-10, a Potential Biomarker of Eosinophilic Airway Inflammation
- (2012) Justin C. Chua et al. PLoS One
- Add-on montelukast vs double-dose budesonide in nonasthmatic eosinophilic bronchitis: A pilot study
- (2012) Chuang Cai et al. RESPIRATORY MEDICINE
- Evaluation and Differential Diagnosis of Marked, Persistent Eosinophilia
- (2012) Rojelio Mejia et al. SEMINARS IN HEMATOLOGY
- Airway Hyperresponsiveness in Asthma: Mechanisms, Clinical Significance, and Treatment
- (2012) John D. Brannan et al. Frontiers in Physiology
- Eosinophil Peroxidase Signals via Epidermal Growth Factor–2 to Induce Cell Proliferation
- (2011) Marie-Therese Walsh et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Activation of β1Integrins on Blood Eosinophils by P-Selectin
- (2011) Mats W. Johansson et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- TPI ASM8 reduces eosinophil progenitors in sputum after allergen challenge
- (2011) H. Imaoka et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Reslizumab in children and adolescents with eosinophilic esophagitis: Results of a double-blind, randomized, placebo-controlled trial
- (2011) Jonathan M. Spergel et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- The development of a sensitive and specific ELISA for mouse eosinophil peroxidase: Assessment of eosinophil degranulation ex vivo and in models of human disease
- (2011) Sergei I. Ochkur et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Eosinophils Regulate Dendritic Cells and Th2 Pulmonary Immune Responses following Allergen Provocation
- (2011) E. A. Jacobsen et al. JOURNAL OF IMMUNOLOGY
- Eosinophils are required for the maintenance of plasma cells in the bone marrow
- (2011) Van Trung Chu et al. NATURE IMMUNOLOGY
- Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis
- (2011) D. Wu et al. SCIENCE
- Role of Transforming Growth Factor–β in Airway Remodeling in Asthma
- (2010) Rabih Halwani et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Effects of oral prednisone on sputum eosinophils and cytokines in patients with severe refractory asthma
- (2010) Federico L. Dente et al. ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
- Eosinophils in innate immunity: an evolving story
- (2010) Revital Shamri et al. CELL AND TISSUE RESEARCH
- Eosinophils as antigen-presenting cells in allergic upper airway disease
- (2010) Praveen Akuthota et al. Current Opinion in Allergy and Clinical Immunology
- Antigen-Specific IgG and IgA, but Not IgE, Activate the Effector Functions of Eosinophils in the Presence of Antigen
- (2010) Masato Muraki et al. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
- Acute Lung Injury: Epidemiology, Pathogenesis, and Treatment
- (2010) Elizabeth R. Johnson et al. Journal of Aerosol Medicine and Pulmonary Drug Delivery
- Statins enhance the anti-inflammatory effects of inhaled corticosteroids in asthmatic patients through increased induction of indoleamine 2, 3-dioxygenase
- (2010) Kittipong Maneechotesuwan et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- IgE, mast cells, basophils, and eosinophils
- (2010) Kelly D. Stone et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- MEDI-563, a humanized anti–IL-5 receptor α mAb with enhanced antibody-dependent cell-mediated cytotoxicity function
- (2010) Roland Kolbeck et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Refining the definition of hypereosinophilic syndrome
- (2010) Hans-Uwe Simon et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- What targeting eosinophils has taught us about their role in diseases
- (2010) Bruce S. Bochner et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- IL-33 Exacerbates Eosinophil-Mediated Airway Inflammation
- (2010) B. Stolarski et al. JOURNAL OF IMMUNOLOGY
- A Randomized Intervention of Montelukast for Post-Bronchiolitis: Effect on Eosinophil Degranulation
- (2010) Chang-Keun Kim et al. JOURNAL OF PEDIATRICS
- A Novel CC-Chemokine Receptor 3 Antagonist, Ki19003, Inhibits Airway Eosinophilia and Subepithelial/Peribronchial Fibrosis Induced by Repeated Antigen Challenge in Mice
- (2010) Masato Komai et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Effects of Aerobic Training on Airway Inflammation in Asthmatic Patients
- (2010) FELIPE AUGUSTO RODRIGUES MENDES et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- Selective Depletion of Eosinophils or Neutrophils in Mice Impacts the Efficiency of Apoptotic Cell Clearance in the Thymus
- (2010) Hye-Jung Kim et al. PLoS One
- Mature human eosinophils express functional Notch ligands mediating eosinophil autocrine regulation
- (2009) A. L. Radke et al. BLOOD
- The hypereosinophilic syndromes: current concepts and treatments
- (2009) Gerald J. Gleich et al. BRITISH JOURNAL OF HAEMATOLOGY
- Human airway smooth muscle promotes eosinophil differentiation
- (2009) A. I. Fanat et al. CLINICAL AND EXPERIMENTAL ALLERGY
- Mouse Eosinophils Possess Potent Antibacterial Properties In Vivo
- (2009) S. N. Linch et al. INFECTION AND IMMUNITY
- Role of atopic status in Toll-like receptor (TLR)7- and TLR9-mediated activation of human eosinophils
- (2009) A. Mansson et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Mepolizumab and Exacerbations of Refractory Eosinophilic Asthma
- (2009) Pranabashis Haldar et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mepolizumab for Prednisone-Dependent Asthma with Sputum Eosinophilia
- (2009) Parameswaran Nair et al. NEW ENGLAND JOURNAL OF MEDICINE
- Effect of omalizumab on peripheral blood eosinophilia in allergic asthma
- (2009) M. Massanari et al. RESPIRATORY MEDICINE
- Eosinophil Cationic Protein Stimulates Migration of Human Lung FibroblastsIn Vitro
- (2009) U. Zagai et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- The role of eosinophil major basic protein in angiogenesis
- (2008) I. Puxeddu et al. ALLERGY
- Human eosinophils constitutively express multiple Th1, Th2, and immunoregulatory cytokines that are secreted rapidly and differentially
- (2008) L. A. Spencer et al. JOURNAL OF LEUKOCYTE BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started