Flecainide exerts paradoxical effects on sodium currents and atrial arrhythmia in murineRyR2-P2328Shearts
出版年份 2015 全文链接
标题
Flecainide exerts paradoxical effects on sodium currents and atrial arrhythmia in murineRyR2-P2328Shearts
作者
关键词
-
出版物
Acta Physiologica
Volume 214, Issue 3, Pages 361-375
出版商
Wiley
发表日期
2015-04-07
DOI
10.1111/apha.12505
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Arrhythmic substrate, slowed propagation and increased dispersion in conduction direction in the right ventricular outflow tract of murineScn5a+/− hearts
- (2014) Y. Zhang et al. Acta Physiologica
- Ryanodine Receptor–Mediated Calcium Leak Drives Progressive Development of an Atrial Fibrillation Substrate in a Transgenic Mouse Model
- (2014) Na Li et al. CIRCULATION
- Suppression of Spontaneous Ca Elevations Prevents Atrial Fibrillation in Calsequestrin 2-Null Hearts
- (2014) Michela Faggioni et al. Circulation-Arrhythmia and Electrophysiology
- CaMKII-dependent regulation of cardiac Na+ homeostasis
- (2014) Eleonora Grandi et al. Frontiers in Pharmacology
- Loss of Nav1.5 expression and function in murine atria containing the RyR2-P2328S gain-of-function mutation
- (2013) James H. King et al. CARDIOVASCULAR RESEARCH
- Flecainide reduces Ca2+ spark and wave frequency via inhibition of the sarcolemmal sodium current
- (2013) Markus B. Sikkel et al. CARDIOVASCULAR RESEARCH
- Calsequestrin 2 deletion causes sinoatrial node dysfunction and atrial arrhythmias associated with altered sarcoplasmic reticulum calcium cycling and degenerative fibrosis within the mouse atrial pacemaker complex1
- (2013) Alexey V. Glukhov et al. EUROPEAN HEART JOURNAL
- Effects of flecainide on exercise-induced ventricular arrhythmias and recurrences in genotype-negative patients with catecholaminergic polymorphic ventricular tachycardia
- (2013) Hiroshi Watanabe et al. HEART RHYTHM
- Determinants of myocardial conduction velocity: implications for arrhythmogenesis
- (2013) James H. King et al. Frontiers in Physiology
- Abnormal Ca2+ homeostasis, atrial arrhythmogenesis, and sinus node dysfunction in murine hearts modeling RyR2 modification
- (2013) Yanmin Zhang et al. Frontiers in Physiology
- Atrial arrhythmia, triggering events and conduction abnormalities in isolated murineRyR2-P2328Shearts
- (2012) J. H. King et al. Acta Physiologica
- Prevalence of atrial fibrillation in the general population and in high-risk groups: the ECHOES study
- (2012) R. C. Davis et al. EUROPACE
- Conduction Slowing Contributes to Spontaneous Ventricular Arrhythmias in Intrinsically Active MurineRyR2-P2328SHearts
- (2012) YANMIN ZHANG et al. JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
- Flecainide-Induced Proarrhythmia Is Attributed to Abnormal Changes in Repolarization and Refractoriness in Perfused Guinea-Pig Heart
- (2012) Oleg E. Osadchii JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Arrhythmogenic left atrial cellular electrophysiology in a murine genetic long QT syndrome model
- (2011) Marc D. Lemoine et al. CARDIOVASCULAR RESEARCH
- Reactive Oxygen Species–Activated Ca/Calmodulin Kinase IIδ Is Required for Late I Na Augmentation Leading to Cellular Na and Ca Overload
- (2011) Stefan Wagner et al. CIRCULATION RESEARCH
- Inherited Dysfunction of Sarcoplasmic Reticulum Ca 2+ Handling and Arrhythmogenesis
- (2011) Silvia G. Priori et al. CIRCULATION RESEARCH
- Short Communication: Flecainide Exerts an Antiarrhythmic Effect in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia by Increasing the Threshold for Triggered Activity
- (2011) Nian Liu et al. CIRCULATION RESEARCH
- Inhibition of Cardiac Ca 2+ Release Channels (RyR2) Determines Efficacy of Class I Antiarrhythmic Drugs in Catecholaminergic Polymorphic Ventricular Tachycardia
- (2011) Hyun Seok Hwang et al. Circulation-Arrhythmia and Electrophysiology
- Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia
- (2011) Christian B. Jung et al. EMBO Molecular Medicine
- Successful treatment of catecholaminergic polymorphic ventricular tachycardia with flecainide: a case report and review of the current literature
- (2011) C. Pott et al. EUROPACE
- Efficacy and potency of class I antiarrhythmic drugs for suppression of Ca2+ waves in permeabilized myocytes lacking calsequestrin
- (2011) Eleonora Savio Galimberti et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Flecainide Therapy Reduces Exercise-Induced Ventricular Arrhythmias in Patients With Catecholaminergic Polymorphic Ventricular Tachycardia
- (2011) Christian van der Werf et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Refractory dispersion promotes conduction disturbance and arrhythmias in a Scn5a +/− mouse model
- (2011) Claire A. Martin et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Acute atrial arrhythmogenicity and altered Ca2+ homeostasis in murine RyR2-P2328S hearts
- (2010) Yanmin Zhang et al. CARDIOVASCULAR RESEARCH
- Acute atrial arrhythmogenesis in murine hearts following enhanced extracellular Ca2+entry depends on intracellular Ca2+stores
- (2009) Y. Zhang et al. Acta Physiologica
- High-Density Substrate Mapping in Brugada Syndrome
- (2009) P.D. Lambiase et al. CIRCULATION
- Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass
- (2009) Fredrick A. Hilliard et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans
- (2009) Hiroshi Watanabe et al. NATURE MEDICINE
- Physiological consequences of theP2328Smutation in the ryanodine receptor (RyR2) gene in genetically modified murine hearts
- (2008) C. A. Goddard et al. Acta Physiologica
- Intracellular calcium modulation of voltage-gated sodium channels in ventricular myocytes
- (2008) Simona Casini et al. CARDIOVASCULAR RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More