Sestrin2 protects against bavachin induced ER stress through AMPK/mTORC1 signaling pathway in HepG2 cells

Chrysophanol attenuates hepatitis B virus X protein-induced hepatic stellate cell fibrosis by regulating endoplasmic reticulum stress and ferroptosis

(2020) Chan-Yen Kuo et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Ionic Liquid-Based Ultrasonic-Assisted Extraction to Analyze Seven Compounds in Psoralea Fructus Coupled with HPLC

(2019) Mengjun Shi et al.   MOLECULES

Ginseng metabolite Protopanaxadiol induces Sestrin2 expression and AMPK activation through GCN2 and PERK

(2019) Hong Ri Jin et al.   Cell Death & Disease

The Role of AMP-Activated Protein Kinase as a Potential Target of Treatment of Hepatocellular Carcinoma

(2019) Xue Jiang et al.   Cancers

A novel AMPK activator improves hepatic lipid metabolism and leukocyte trafficking in experimental hepatic steatosis

(2019) Xueying Peng et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

MiR-4756 promotes albumin-induced renal tubular epithelial cell epithelial-to-mesenchymal transition and endoplasmic reticulum stress via targeting Sestrin2

(2018) Yijie Jia et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Protein Quality Control in the Endoplasmic Reticulum and Cancer

(2018) Hye Won Moon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Redox signaling and unfolded protein response coordinate cell fate decisions under ER stress

(2018) Zhe Zhang et al.   Redox Biology

Drug-Induced Liver Injury: Cascade of Events Leading to Cell Death, Apoptosis or Necrosis

(2017) Andrea Iorga et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases

(2017) Mazhar Pasha et al.   Oxidative Medicine and Cellular Longevity

Sestrin-2 is significantly increased in malignant pleural effusions due to lung cancer and is potentially secreted by pleural mesothelial cells

(2016) Irene Tsilioni et al.   CLINICAL BIOCHEMISTRY

Quantitative Analysis of Psoralea corylifolia Linne and its Neuroprotective and Anti-Neuroinflammatory Effects in HT22 Hippocampal Cells and BV-2 Microglia

(2016) Yu Kim et al.   MOLECULES

Targeting endoplasmic reticulum stress in liver disease

(2016) Fa-Ling Wu et al.   Expert Review of Gastroenterology & Hepatology

Sestrin2 is induced by glucose starvation via the unfolded protein response and protects cells from non-canonical necroptotic cell death

(2016) Boxiao Ding et al.   Scientific Reports

Identification and characterization of naturally occurring inhibitors against UDP-glucuronosyltransferase 1A1 in Fructus Psoraleae (Bu-gu-zhi)

(2015) Xin-Xin Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Protein kinase R-like ER kinase and its role in endoplasmic reticulum stress-decided cell fate

(2015) Z Liu et al.   Cell Death & Disease

Janus-faced Sestrin2 controls ROS and mTOR signalling through two separate functional domains

(2015) Hanseong Kim et al.   Nature Communications

Hepatoprotective role of Sestrin2 against chronic ER stress

(2014) Hwan-Woo Park et al.   Nature Communications

Sestrins Orchestrate Cellular Metabolism to Attenuate Aging

(2013) Jun Hee Lee et al.   Cell Metabolism

Dysregulated mTORC1 renders cells critically dependent on desaturated lipids for survival under tumor-like stress

(2013) R. M. Young et al.   GENES & DEVELOPMENT

Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling

(2012) Christian Appenzeller-Herzog et al.   TRENDS IN CELL BIOLOGY

mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1–JNK pathway

(2011) H Kato et al.   CELL DEATH AND DIFFERENTIATION

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress

(2011) Brian F. Teske et al.   MOLECULAR BIOLOGY OF THE CELL

Stress-Responsive Sestrins Link p53 with Redox Regulation and Mammalian Target of Rapamycin Signaling

(2010) Andrei V. Budanov   ANTIOXIDANTS & REDOX SIGNALING

The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis

(2010) Y J Kang et al.   CELL DEATH AND DIFFERENTIATION

The mechanism of eukaryotic translation initiation and principles of its regulation

(2010) Richard J. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sestrin as a Feedback Inhibitor of TOR That Prevents Age-Related Pathologies

(2010) J. H. Lee et al.   SCIENCE

p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling

(2008) Andrei V. Budanov et al.   CELL