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Systematic review on wearable lower-limb exoskeletons for gait training in neuromuscular impairments

出版社

BMC
DOI: 10.1186/s12984-021-00815-5

关键词

Wearable exoskeleton; Lower-limb; Neuromuscular impairment; Gait rehabilitation; Spinal cord injury; Stroke

资金

  1. Agency for Management of University and Research Grants (AGAUR) [2020 FI_B1 00195]
  2. Secretariat of Universities and Research of the Catalan Ministry of Business and Knowledge
  3. European Social Fund (ESF)
  4. Spanish Ministry of Science and Innovation (MCI) -Agencia Estatal de Investigacion (AEI) [RTI2018-097290-B-C33, PTQ2018-010227]
  5. European Regional Development Fund (ERDF)

向作者/读者索取更多资源

Wearable lower-limb exoskeletons show potential for improving walking ability, promoting exercise, and enhancing daily living activities for individuals with neuromuscular impairments. However, current limitations such as bulky devices and limited evidence of benefits in short-term trials highlight the need for further research and clinical trials to demonstrate their efficacy.
Gait disorders can reduce the quality of life for people with neuromuscular impairments. Therefore, walking recovery is one of the main priorities for counteracting sedentary lifestyle, reducing secondary health conditions and restoring legged mobility. At present, wearable powered lower-limb exoskeletons are emerging as a revolutionary technology for robotic gait rehabilitation. This systematic review provides a comprehensive overview on wearable lower-limb exoskeletons for people with neuromuscular impairments, addressing the following three questions: (1) what is the current technological status of wearable lower-limb exoskeletons for gait rehabilitation?, (2) what is the methodology used in the clinical validations of wearable lower-limb exoskeletons?, and (3) what are the benefits and current evidence on clinical efficacy of wearable lower-limb exoskeletons? We analyzed 87 clinical studies focusing on both device technology (e.g., actuators, sensors, structure) and clinical aspects (e.g., training protocol, outcome measures, patient impairments), and make available the database with all the compiled information. The results of the literature survey reveal that wearable exoskeletons have potential for a number of applications including early rehabilitation, promoting physical exercise, and carrying out daily living activities both at home and the community. Likewise, wearable exoskeletons may improve mobility and independence in non-ambulatory people, and may reduce secondary health conditions related to sedentariness, with all the advantages that this entails. However, the use of this technology is still limited by heavy and bulky devices, which require supervision and the use of walking aids. In addition, evidence supporting their benefits is still limited to short-intervention trials with few participants and diversity among their clinical protocols. Wearable lower-limb exoskeletons for gait rehabilitation are still in their early stages of development and randomized control trials are needed to demonstrate their clinical efficacy.

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