Exploring the Chemistry of Alkaloids from Malaysian Mitragyna speciosa (Kratom) and the Role of Oxindoles on Human Opioid Receptors

Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for Mu-Opioid Receptor and Opioid-Like Behavioral Effects in Rats

(2021) Samuel Obeng et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Evaluating kratom alkaloids using PHASE

(2020) Christopher R. Ellis et al.   PLoS One

The Chemistry of Kratom [Mitragyna speciosa]: Updated Characterization Data and Methods to Elucidate Indole and Oxindole Alkaloids

(2020) Laura Flores-Bocanegra et al.   JOURNAL OF NATURAL PRODUCTS

Pharmacokinetics and Safety of Mitragynine in Beagle Dogs

(2020) Elizabeth A. Maxwell et al.   PLANTA MEDICA

Modeling cannabinoids from a large-scale sample of Cannabis sativa chemotypes

(2020) Daniela Vergara et al.   PLoS One

Simultaneous quantification of ten key Kratom alkaloids in Mitragyna speciosa leaf extracts and commercial products by ultra‐performance liquid chromatography−tandem mass spectrometry

(2019) Abhisheak Sharma et al.   Drug Testing and Analysis

7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects

(2019) Andrew C. Kruegel et al.   ACS Central Science

Investigation of the Adrenergic and Opioid Binding Affinities, Metabolic Stability, Plasma Protein Binding Properties, and Functional Effects of Selected Indole-Based Kratom Alkaloids

(2019) Samuel Obeng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Seasonality effect on the composition of oxindole alkaloids from distinct organs of Uncaria tomentosa from the Caribbean region of Costa Rica

(2018) Silvana Alvarenga-Venutolo et al.   PHYTOCHEMISTRY

Changing trends in the use of kratom (Mitragyna speciosa ) in Southeast Asia

(2017) Darshan Singh et al.   HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL

A botanical, phytochemical and ethnomedicinal review of the genus Mitragyna korth: Implications for products sold as kratom

(2017) Paula N. Brown et al.   JOURNAL OF ETHNOPHARMACOLOGY

Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators

(2016) Andrew C. Kruegel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Circulating ultrasound-assisted extraction, countercurrent chromatography, and liquid chromatography for the simultaneous extraction, isolation, and analysis of the constituents of Uncaria tomentosa

(2015) Yuchi Zhang et al.   JOURNAL OF CHROMATOGRAPHY A

CHEMICAL COMPOSITION VARIABILITY IN THEUncaria tomentosa(cat's claw) WILD POPULATION

(2015) Evelyn Maribel Condori Peñaloza et al.   QUIMICA NOVA

Total Synthesis of the Spirocyclic Oxindole Alkaloids Corynoxine, Corynoxine B, Corynoxeine, and Rhynchophylline

(2013) Martin J. Wanner et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A review on indole alkaloids isolated from Uncaria rhynchophylla and their pharmacological studies

(2013) Andre Ndagijimana et al.   FITOTERAPIA

Monoterpene indole alkaloids from the stem bark of Mitragyna diversifolia and their acetylcholine esterase inhibitory effects

(2013) Xing-Fen Cao et al.   PHYTOCHEMISTRY

Isolation, characterization, and NMR spectroscopic data of indole and oxindole alkaloids from Mitragyna speciosa

(2013) Zulfiqar Ali et al.   TETRAHEDRON LETTERS

Macrophyllionium and Macrophyllines A and B, Oxindole Alkaloids fromUncaria macrophylla

(2010) Kou Wang et al.   JOURNAL OF NATURAL PRODUCTS

Structure validation in chemical crystallography

(2009) Anthony L. Spek   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY