A structurally optimized FXR agonist, MET409, reduced liver fat content over 12 weeks in patients with non-alcoholic steatohepatitis
出版年份 2021 全文链接
标题
A structurally optimized FXR agonist, MET409, reduced liver fat content over 12 weeks in patients with non-alcoholic steatohepatitis
作者
关键词
Farnesoid X Receptor, Magnetic Resonance Imaging-Proton Density Fat Fraction, Metabolic Liver Disease, Nonalcoholic Steatohepatitis
出版物
JOURNAL OF HEPATOLOGY
Volume -, Issue -, Pages -
出版商
Elsevier BV
发表日期
2021-02-11
DOI
10.1016/j.jhep.2021.01.047
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Multicenter validation of association between decline in MRI‐PDFF and histologic response in nonalcoholic steatohepatitis
- (2020) Rohit Loomba et al. HEPATOLOGY
- Cilofexor, a Nonsteroidal FXR Agonist, in Non‐Cirrhotic Patients with Nonalcoholic Steatohepatitis: A Phase 2 Randomized Controlled Trial
- (2020) Keyur Patel et al. HEPATOLOGY
- FXR Agonists as Therapy for Liver Disease
- (2020) Jay H. Hoofnagle HEPATOLOGY
- Nidufexor, a non-bile acid FXR agonist, decreases ALT and hepatic fat fraction in patients with NASH after 12 weeks dosing
- (2020) Richard Aspinall et al. JOURNAL OF HEPATOLOGY
- Magnetic resonance imaging-proton density fat fraction (MRI-PDFF) to predict treatment response on NASH liver biopsy: a secondary analysis of the resmetirom randomized placebo-controlled phase 2 clinical trial
- (2020) Rohit Loomba et al. JOURNAL OF HEPATOLOGY
- Type 2 diabetes mellitus is a risk factor for progression of liver fibrosis in middle‐aged patients with nonalcoholic fatty liver disease
- (2019) Toshifumi Tada et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- Molecular tuning of farnesoid X receptor partial agonism
- (2019) Daniel Merk et al. Nature Communications
- Economic and Clinical Burden of Nonalcoholic Steatohepatitis in Patients With Type 2 Diabetes in the United States
- (2019) Zobair M. Younossi et al. DIABETES CARE
- Resmetirom (MGL-3196) for the treatment of non-alcoholic steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial
- (2019) Stephen A Harrison et al. LANCET
- Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial
- (2019) Zobair M Younossi et al. LANCET
- Magnetic Resonance vs Transient Elastography Analysis of Patients With Non-alcoholic Fatty Liver Disease: a Systematic Review and Pooled Analysis of Individual Participants
- (2018) Cynthia Hsu et al. Clinical Gastroenterology and Hepatology
- Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease
- (2017) Chris Estes et al. HEPATOLOGY
- Increased risk of mortality by fibrosis stage in nonalcoholic fatty liver disease: Systematic review and meta-analysis
- (2017) Parambir S. Dulai et al. HEPATOLOGY
- Quantification of Hepatic Steatosis With a Multistep Adaptive Fitting MRI Approach: Prospective Validation Against MR Spectroscopy
- (2015) Mustafa R. Bashir et al. AMERICAN JOURNAL OF ROENTGENOLOGY
- Nonalcoholic Fatty Liver Disease
- (2015) Mary E. Rinella JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Multiparametric magnetic resonance for the non-invasive diagnosis of liver disease
- (2013) Rajarshi Banerjee et al. JOURNAL OF HEPATOLOGY
- Liver fat quantification using a multi-step adaptive fitting approach with multi-echo GRE imaging
- (2013) Xiaodong Zhong et al. MAGNETIC RESONANCE IN MEDICINE
- Bile-acid-activated receptors: targeting TGR5 and farnesoid-X-receptor in lipid and glucose disorders
- (2009) Stefano Fiorucci et al. TRENDS IN PHARMACOLOGICAL SCIENCES
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search