3-MCPD and glycidol coexposure induces systemic toxicity and synergistic nephrotoxicity via NLRP3 inflammasome activation, necroptosis, and autophagic cell death

Contribution of TGF-Beta-Mediated NLRP3-HMGB1 Activation to Tubulointerstitial Fibrosis in Rat With Angiotensin II-Induced Chronic Kidney Disease

(2020) Kaimin Zhang et al.   Frontiers in Cell and Developmental Biology

Autophagy in Chronic Kidney Diseases

(2019) Tien-An Lin et al.   Cells

Fatty Acid Esters of 3-Monochloropropanediol: A Review

(2019) Boyan Gao et al.   Annual Review of Food Science and Technology

Cell Death in the Kidney

(2019) Giovanna Priante et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease

(2019) Youliang Wang et al.   Frontiers in Endocrinology

Gasdermin D and pyroptosis in acute kidney injury

(2019) Wulf Tonnus et al.   KIDNEY INTERNATIONAL

Metabolomics-based biomarker analysis of dihydroxypropyl mercapturic acid isomers from 3-monochloropropane-1,2-diol and glycidol for evaluation of toxicokinetics in rats and daily internal exposure in humans

(2019) Wei Jia et al.   TALANTA

The Role of Inflammasome-Dependent and Inflammasome-Independent NLRP3 in the Kidney

(2019) Yang Gyun Kim et al.   Cells

Targeting of regulated necrosis in kidney disease

(2018) Diego Martin-Sanchez et al.   NEFROLOGIA

Necroptosis in 3-chloro-1, 2-propanediol (3-MCPD)-dipalmitate-induced acute kidney injury in vivo and its repression by miR-223-3p

(2018) Guoren Huang et al.   TOXICOLOGY

Esters of 3-chloropropane-1,2-diol in foodstuffs

(2018) B. Svejkovská et al.   CZECH JOURNAL OF FOOD SCIENCES

Toxicokinetics and Metabolism of 3-Monochloropropane 1,2-Diol Dipalmitate in Sprague Dawley Rats

(2018) Guoren Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Pathway of 3-MCPD-induced apoptosis in human embryonic kidney cells

(2017) Jian Ji et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

C10ORF10/DEPP-mediated ROS accumulation is a critical modulator of FOXO3-induced autophagy

(2017) S. Salcher et al.   Molecular Cancer

Time to target uric acid to retard CKD progression

(2016) Takanori Kumagai et al.   Clinical and Experimental Nephrology

Preparation of five 3-MCPD fatty acid esters, and the effects of their chemical structures on acute oral toxicity in Swiss mice

(2016) Man Liu et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Estimation of the Intestinal Absorption and Metabolism Behaviors of 2- and 3-Monochloropropanediol Esters

(2016) Naoki Kaze et al.   LIPIDS

3-Monochloro-1,2-propanediol (3-MCPD) induces apoptosis via mitochondrial oxidative phosphorylation system impairment and the caspase cascade pathway

(2016) Xiaoli Peng et al.   TOXICOLOGY

Flow Cytometry-Based Assessment of Mitophagy Using MitoTracker

(2016) Bin Xiao et al.   Frontiers in Cellular Neuroscience

A 28-day oral gavage toxicity study of 3-monochloropropane-1,2-diol (3-MCPD) in CB6F1-non-Tg rasH2 mice

(2015) Byoung-Seok Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

Transcriptional regulation of tenascin genes

(2015) Francesca Chiovaro et al.   Cell Adhesion & Migration

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Renal Organic Anion Transporters (SLC22 Family): Expression, Regulation, Roles in Toxicity, and Impact on Injury and Disease

(2012) Li Wang et al.   AAPS Journal

Expression of human carbonyl reductase 3 (CBR3; SDR21C2) is inducible by pro-inflammatory stimuli

(2012) Petra Malátková et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NGAL (Lcn2) monomer is associated with tubulointerstitial damage in chronic kidney disease

(2012) Thomas L. Nickolas et al.   KIDNEY INTERNATIONAL

Toxicological assessment of 3-chloropropane-1,2-diol and glycidol fatty acid esters in food

(2011) Nadiya Bakhiya et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY