Article
Environmental Studies
Eusebio Cano, Ana Cano-Ortiz, Jose Carlos Pinar Fuentes, Ricardo Quinto-Canas, Jehad Igbareyeh, Sara del Rio, Carlos Jose Pinto Gomes
Summary: This study reviews the natural communities of Pinus halepensis in Spain. Analysis of 400 plant communities resulted in the proposal of new associations and alliances. The study also suggests a new ombroedaphoxeric index for diagnosing the communities. The findings provide valuable information for reforestation efforts in accordance with the natural environment.
Article
Environmental Sciences
Pegah Kharazian, Giovanna Cappai, Maria Enrica Boi, Marco Porceddu, Martina Piredda, Giovanni De Giudici, Gianluigi Bacchetta
Summary: This study evaluated the phytoremediation potential of Pinus halepensis in abandoned mine-tailing, showing that the plant has good adaptability in contaminated substrates. The addition of compost amendment can restrict the bioavailability and accumulation of metals in the aerial parts of the plant.
INTERNATIONAL JOURNAL OF PHYTOREMEDIATION
(2023)
Article
Forestry
Mehdi Navidi, Manuel Esteban Lucas-Borja, Pedro Antonio Plaza-Alvarez, Bruno Gianmarco Carra, Misagh Parhizkar, Demetrio Antonio Zema
Summary: Straw mulching and salvage logging may disturb burned soils and affect natural regeneration of forest species. This study found that after a wildfire and four years of post-fire treatments, areas with straw mulching and no logging showed better regeneration of Pinus halepensis Mill., while logging did not significantly increase the number of seedlings and had negative effects on their size and height.
Review
Chemistry, Medicinal
Marcelo D. Catarino, Rita Silva-Reis, Amina Chouh, Sonia Silva, Susana S. Braga, Artur M. S. Silva, Susana M. Cardoso
Summary: This article provides an overview of Sargassum seaweeds, one of the largest and most diverse genus of brown seaweeds, comprising around 400 taxonomically accepted species. Many species of this genus have long been used in human culture for food, feed, and folk medicine. Besides their high nutritional value, these seaweeds are also rich in natural antioxidant compounds, such as polyphenols, carotenoids, meroterpenoids, and phytosterols. These compounds have important applications in various fields, including agriculture, food, and health, and can be used for product preservation, cosmetics, and crop production improvement.
Article
Environmental Sciences
Nuria J. Elvira, Francisco Lloret, Luciana Jaime, Jordi Margalef-Marrase, Maria Angeles Perez Navarro, Enric Batllori
Summary: Fire and drought are two major factors shaping Mediterranean ecosystems. This study investigated the success of post-fire regeneration of Pinta halepensis under compound fire-drought regimes. Results showed that fire severity, temperature deviations, and precipitation deviations all played a role in determining pine tree regeneration density.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Review
Pharmacology & Pharmacy
Chen-Chen Fu, Fa-Ying Xu, Yu-Chen Qian, Hoi-Lun Koo, Yi-Fan Duan, Geng-Min Weng, Tai-Ping Fan, Mo-Xian Chen, Fu-Yuan Zhu
Summary: Osmanthus fragrans, a flowering plant with a long history of cultivation in China, has not only edible and ornamental value, but also medicinal value. Its secondary metabolites, including flavonoids, terpenes, and phenolic acids, have antioxidant, anticancer, anti-inflammatory, and antibacterial activities, and can be used to treat various human diseases.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Environmental Sciences
Yuwei Zhou, Jingxin He, Hui Cui
Summary: The fungi Eutypella have the ability to produce a wide array of natural products with unique structures and diverse bioactivities. These natural products are considered as promising sources for lead compounds in drug discovery. This review provides a systematic summary of the structures and bioactivities of secondary metabolites produced by Eutypella, highlighting the predominance of terpenoids and alkaloids. It also emphasizes the significant antiproliferative activity of these metabolites. The findings in this review offer a new perspective for the development of new drugs by pharmacologists.
FRONTIERS IN MARINE SCIENCE
(2022)
Review
Horticulture
Hanbin Wu, Ke Yang, Liwei Dong, Jiabao Ye, Feng Xu
Summary: Matricaria chamomilla is a versatile aromatic medicinal plant used for treating flatulence, inflammation, and pain, with terpenes and flavonoids as its main active components.
Article
Food Science & Technology
Amani Mahdhi, Hanene Ghazghazi, Meriem El Aloui, Ridha Ben Salem, Ghayth Rigane
Summary: This study evaluated the chemical composition and antioxidant activities of Aleppo Pine seeds oil and methanolic-aqueous extract, finding that seeds obtained through different drying methods showed varying levels of phenolic compounds, with seeds dried by sun method exhibiting higher antioxidant activities. The research provides insights for industry in producing potentially bioactive plant extracts.
FOOD SCIENCE & NUTRITION
(2021)
Article
Biochemistry & Molecular Biology
Paula Alexandra Postu, Marius Mihasan, Dragos Lucian Gorgan, Fatima Zahra Sadiki, Mostafa El Idrissi, Lucian Hritcu
Summary: The present study evaluated the potential medicinal effects of Pinus halepensis Mill. essential oil (PNO) in an Alzheimer's disease (AD) environment. The results showed that PNO has anxiolytic and antidepressant properties and can restore redox imbalance in rats with AD-like neuropsychiatric impairments. Additionally, PNO demonstrated beneficial effects against neuroinflammation and neuroapoptosis in the AD rat model induced by amyloid beta1-42 (A beta 1-42).
Article
Forestry
Rodolfo Zapata, Jose-Vicente Oliver-Villanueva, Lenin-Guillermo Lemus-Zuniga, Miguel A. Mateo Pla, Jorge E. Luzuriaga
Summary: Aleppo pine forests are at high risk of wildfires during drought, with high temperatures and water stress. Electrical responses can be a valuable variable in fire risk management models, showing significant variations correlated with favorable meteorological conditions for wildfires. Voltage variation is influenced by plant behavior and physiological responses to drought stress.
Article
Environmental Sciences
Pedro Antonio Plaza-Alvarez, Daniel Moya, Manuel Esteban Lucas-Borja, Fuensanta Garcia-Orenes, Javier Gonzalez-Romero, Carlos Rossa, Esther Pena, Jorge De las Heras
Summary: This study evaluated the short-term effects of prescribed burnings on soil physico-chemical and biological properties, finding that it can decrease understory vegetation cover while reducing soil biological functions in areas with poorly developed soil and a dry climate.
LAND DEGRADATION & DEVELOPMENT
(2021)
Article
Biochemistry & Molecular Biology
Hye Jin Kim, Xiao-Jun Li, Dong-Cheol Kim, Tai Kyoung Kim, Jae Hak Sohn, Haeun Kwon, Dongho Lee, Youn-Chul Kim, Joung Han Yim, Hyuncheol Oh
Summary: Chemical investigation of the Antarctic lichen-derived fungal strain Acremonium sp. SF-7394 led to the discovery of new amphilectane-type diterpene and acorane-type sesquiterpene glycoside, along with known fungal metabolites. One of the diterpenes demonstrated competitive inhibition of protein tyrosine phosphatase 1B.
Review
Biotechnology & Applied Microbiology
Ushasree Mrudulakumari Vasudevan, Dung Hoang Anh Mai, Shyam Krishna, Eun Yeol Lee
Summary: Methanotrophs have the potential to produce various bioactive secondary metabolites including iso-prenoids, polymers, peptides, and vitamins. Genome mining of these microbes revealed the hidden biosynthetic potential of these microbes. Through advanced synthetic biology tools, the central carbon metabolism in methanotrophs can be modified to produce valuable secondary metabolites. This review summarizes the possibilities of developing methanotrophs as microbial chassis for high-value secondary metabolites.
BIOTECHNOLOGY ADVANCES
(2023)
Article
Agronomy
Domina Delac, Ivica Kisic, Paulo Pereira
Summary: This study evaluates the effects of mulch treatments on soil quality after a wildfire, showing that mulching can increase soil aggregate stability and hydraulic conductivity, as well as improve soil nutrient content. Using mulch is recommended as an effective method for improving soil quality after a wildfire.
Review
Food Science & Technology
Muthu Thiruvengadam, Umadevi Subramanian, Baskar Venkidasamy, Prabhu Thirupathi, Ramkumar Samynathan, Mohammad Ali Shariati, Maksim Rebezov, Ill-Min Chung, Kannan R. R. Rengasamy
Summary: Understanding the gut microbiota has become crucial in maintaining human body's homeostasis and preventing disease development. Short-chain fatty acids, produced by gut microbiota fermentation of dietary fiber, play a significant role in modulating the tumor environment and binding to carcinogens for elimination. The gut microbiota may offer new approaches for cancer therapy in the future.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Food Science & Technology
Naoufal E. L. Hachlafi, Tariq Aanniz, Naoual El Menyiy, Aicha El Baaboua, Nasreddine El Omari, Abdelaali Balahbib, Mohammad Ali Shariati, Gokhan Zengin, Kawtar Fikri-Benbrahim, Abdelhakim Bouyahya
Summary: Camphene, a volatile compound found in various aromatic and medicinal plants, has shown multiple biological activities. This review summarizes its biological properties, mechanisms of action, and potential applications as a drug. Further research is needed to validate its use in the pharmaceutical field.
FOOD REVIEWS INTERNATIONAL
(2023)
Review
Food Science & Technology
Mohammed Saber, Naoual El Menyiy, Saoulajan Charfi, Hanae Naceiri Mrabti, Omar Belmehdi, Hamza El Moudden, Douae Taha, Nasreddine El Omari, Abdelaali Balahbib, Gokhan Zengin, Mohamed Bakha, Mohamed Tabyaoui, Hicham Harhar, Monica Gallo, Domenico Montesano, Abdelhakim Bouyahya
Summary: This article reports previous investigations on Tetraclinis articulata, including its taxonomy, distribution, traditional use, phytochemistry, biological effects, toxicology, nutritional value, and economic interest. The plant exhibits various biological activities and shows no toxicity. However, further research is needed to validate its pharmacological use and toxicity.
FOOD REVIEWS INTERNATIONAL
(2023)
Review
Food Science & Technology
Maksim Rebezov, Muhammad Usman Khan, Abdelhakim Bouyahya, Muhammad Imran, Tabussam Tufail, Olga Loretts, Olga Neverova, Svetlana Artyukhova, Elena Kuznetsova, Vladimir Ermolaev, Abdelaali Balahbib, Muthu Thiruvengadam, Gokhan Zengin, Mohammad Ali Shariati
Summary: Tiger nuts are a nutritional plant with tubers rich in vegetable oils and other beneficial compounds. Tiger nut oil is underutilized in the food industry, but its dietary fibers can be used to prepare fiber-rich meat products. Tiger nuts and their by-products have potential applications in the food industry, pharmaceuticals, agricultural development, and biofuel production.
FOOD REVIEWS INTERNATIONAL
(2023)
Article
Biochemistry & Molecular Biology
Loai M. H. Eltayeb, Sakina Yagi, Hanan M. M. Mohamed, Gokhan Zengin, Mohammad Ali Shariati, Maksim Rebezov, Abdullah Ibrahim Uba, Jose Manuel Lorenzo
Summary: This study aimed to determine the chemical composition, antioxidant and enzyme inhibitory activities of essential oils extracted from Chamaecyparis obtusa, Chrysopogon nigritanus, and Lavandula coronopifolia. The results showed that these essential oils have promising functional properties for food, cosmetics, and pharmaceutical applications.
Article
Biochemistry & Molecular Biology
Alessandra Acquaviva, Abdelhakim Nilofar, Abdelhakim Bouyahya, Gokhan Zengin, Simonetta Cristina Di Simone, Lucia Recinella, Sheila Leone, Luigi Brunetti, Abdullahi Ibrahim Uba, Ugur Cakilcioglu, Ridvan Polat, Ekrem Darendelioglu, Luigi Menghini, Claudio Ferrante, Maria Loreta Libero, Giustino Orlando, Annalisa Chiavaroli
Summary: This study aimed to evaluate the effects of different polarity extracts from Artemisia annua on inflammation and oxidative stress in colon tissue exposed to LPS. The water extract showed the highest phenolic content and antioxidant activity, while the hexane extract exhibited the best enzyme inhibition effects. All extracts demonstrated effective anti-inflammatory effects by reducing COX-2 and TNFα gene expression. These findings suggest the potential use of water extract in the management of inflammatory colon diseases.
CHEMISTRY & BIODIVERSITY
(2023)
Review
Food Science & Technology
Fatema R. Saber, Paulo E. S. Munekata, Komal Rizwan, Heba A. S. El-Nashar, Nouran M. Fahmy, Shaza H. Aly, Mohamed El-Shazly, Abdelhakim Bouyahya, Jose M. Lorenzo
Summary: Myrtaceae is an important flowering plant family, including various genera of ecological and economic importance. The extraction of bioactive compounds from Myrtaceae plants has been improved through the optimization of traditional methods and the use of emerging technologies. Encapsulation and delivery systems have shown promising results in producing stable essential oil nanoemulsions and liposomes. The application of Myrtaceae extracts in the pharmaceutical field and certain plants in the food area has also demonstrated interesting results. However, further advancements are needed to optimize environmentally friendly extraction methods and conduct risk assessment studies for their full potential in various applications.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Food Science & Technology
Saad Bakrim, Sara Aboulaghras, Tarik Aanniz, Taoufiq Benali, Nasreddine El Omari, Mohamed El-Shazly, Learn-Han Lee, Syed Khalid Mustafa, Nargis Sahib, Maksim Rebezov, Mohammad Ali Shariati, Jose M. M. Lorenzo, Abdelhakim Bouyahya
Summary: The field of nutrigenomics studies the interaction between nutrition and genetics, and how certain dietary patterns can impact gene expression and overall health. The Mediterranean diet, characterized by a high intake of fruits, vegetables, whole grains, and healthy fats, has been linked to better cardiovascular health outcomes. This review summarizes the current state of research on the effects of nutrigenomics and the Mediterranean diet on cardiovascular health.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Chemistry, Analytical
Andrey V. V. Blinov, David G. G. Maglakelidze, Zafar A. A. Rekhman, Maria A. A. Yasnaya, Alexey A. A. Gvozdenko, Alexey B. B. Golik, Anastasiya A. A. Blinova, Maxim A. A. Kolodkin, Naiyf S. S. Alharbi, Shine Kadaikunnan, Muthu Thiruvengadam, Mohammad Ali Shariati, Andrey A. A. Nagdalian
Summary: This article presents the synthesis of selenium nanoparticles (Se NPs) stabilized by a quaternary ammonium compound-catamine AB. The Se NPs were obtained through chemical reduction in an aqueous medium. The optimization of the synthesis method and the characterization of the particle size and stability of the Se NPs were conducted. The results showed a bimodal distribution in negatively charged particles and the influence of active acidity and ionic strength on the stability of the Se NPs sols.
Article
Plant Sciences
Ebru Yuce Babacan, Dimitrina Zheleva-Dimitrova, Reneta Gevrenova, Abdelhakim Bouyahya, Mehmet Maruf Balos, Ugur Cakilcioglu, Kouadio Ibrahime Sinan, Gokhan Zengin
Summary: The study analyzed the metabolite profiles and evaluated the antioxidant and enzyme inhibitory properties of methanol extracts from flowers, leaves, and tubers of Eminium intortum and E. spiculatum. A total of 83 metabolites were identified for the first time, including phenolic acids, flavonoids, amino acids, and fatty acids. E. intortum showed high phenolic and flavonoid contents in flowers and leaves, while leaf extracts exhibited significant radical scavenging activity and reducing power. E. spiculatum showed high inhibition towards α-glucosidase and tyrosinase in leaves and tubers, respectively. Both species have the potential to be used as functional ingredients in the pharmaceutical and nutraceutical industries.
Article
Plant Sciences
Taoufiq Benali, Ahmed Lemhadri, Kaoutar Harboul, Houda Chtibi, Abdelmajid Khabbach, Si Mohamed Jadouali, Luisa Quesada-Romero, Said Louahlia, Khalil Hammani, Adib Ghaleb, Learn-Han Lee, Abdelhakim Bouyahya, Marius Emil Rusu, Mohamed Akhazzane
Summary: The aim of this study was to determine the chemical compounds of Lavandula stoechas essential oil and investigate its antibacterial, anticandidal, and antioxidant effects, as well as its in silico anti-SARS-CoV-2 activity. The results showed variation in the chemical composition of the oil depending on the site of growth. The oil exhibited significant antioxidant, antibacterial, anticandidal, and anti-SARS-CoV-2 activities.
Article
Chemistry, Multidisciplinary
Igor Rzhepakovsky, Sergei Piskov, Svetlana Avanesyan, Magomed Shakhbanov, Marina Sizonenko, Lyudmila Timchenko, Mohammad Ali Shariati, Maksim Rebezov, Andrey Nagdalian
Summary: X-ray contrast techniques were tested on chick embryos in the early stages of embryogenesis. It was found that staining with 1% phosphotungstic acid through heating provided reliable microtomographic results, allowing for the visualization and analysis of the locations and structures of chick embryo organs. The study opens up significant prospects for using chick embryos as an alternative model for screening teratogenicity.
APPLIED SCIENCES-BASEL
(2023)
Article
Biochemistry & Molecular Biology
Gokhan Zengin, Nilofar, Evren Yildiztugay, Abdelhakim Bouyahya, Halit Cavusoglu, Reneta Gevrenova, Dimitrina Zheleva-Dimitrova
Summary: This study extracted phytochemicals from Inula sarana using various solvents and analyzed their content and activities. The 70% ethanol extract contained the highest phenolic content and exhibited strong antioxidant and enzyme inhibitory activities.
Review
Plant Sciences
Ramkumar Samynathan, Baskar Venkidasamy, Mohammad Ali Shariati, Pandiyan Muthuramalingam, Muthu Thiruvengadam
Summary: Strigolactones (SLs) are important endogenous plant hormones that play a role in plant and rhizosphere interactions by controlling mycorrhization and lateral shoot branching. They participate in plant architecture development, bud outgrowth reduction, and other morphological and developmental processes. Strigolactones regulate root growth and structure by inhibiting lateral root production and enhancing root hair elongation. Targeted genetic engineering of SL biosynthetic genes can lead to changes in root and vegetative systems and help in generating plants that are more suited to different adverse environmental conditions.
BRAZILIAN JOURNAL OF BOTANY
(2023)
Correction
Plant Sciences
Lingmiao Wen, Tinglan Zhang, Fangfang Chen, Lin Hu, Chongyang Dou, Xian Ding, Alvin Altamirano, Guihua Wei, Zhiyong Yan
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Qing Tang, Mengfei Xu, Shunqin Long, Yaya Yu, Changju Ma, Rui Wang, Jing Li, Xi Wang, Fang Fang, Ling Han, Wanyin Wu, Sumei Wang
Summary: This study demonstrates that Fuzheng Kang-Ai (FZKA) decoction can inhibit the cell growth, proliferation, and invasion of lung adenocarcinoma (LUAD) and reverse the acquired resistance of gefitinib. FZKA exerts its effects by regulating the p-ERK1/2-EZH2-Snail/EGFR signaling pathway.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Xiang Zhao, Xianrun Hu, Qi Xie, Shenglan Qi, Zedong Xiang, Xin Sun, Zhejun Xie, Rui Dang, Limei Zhou, Wei Liu, Xuemei Cheng, Changhong Wang
Summary: This study investigated the effects of Fufangmuniziqi formula (FFMN) on Alzheimer's disease (AD) and the role of alkaloids, flavonoids, and saponins in the process. The results showed that FFMN improved cognitive and memory impairment in the AD mouse model. Alkaloids enhanced the cholinergic system, while flavonoids and saponins attenuated neuroinflammation and oxidative stress. These findings suggest that the combination of alkaloid, flavonoid, and saponin fractions derived from FFMN is a promising anti-AD agent.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Bangjian Dong, Ying Peng, Mengyue Wang, Chongsheng Peng, Xiaobo Li
Summary: This study elucidated the tissue distribution and excretion characteristics of the non-polysaccharide components of Sijunzi decoction in rats with spleen deficiency syndrome. It proposed new insights into the rationality of the compatibility of Sijunzi decoction.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Jung-Seop Kim, Man-Gi Kim, Ji Eun Ryu, Ye-Been Lee, Quan Feng Liu, Kwang Ki Kim, Seung-Hun Cho, Sung Joon Shin, Byung-Soo Koo, Hyung-Kyoon Choi
Summary: Co-treatment with WCW and donepezil shows promise in improving cognitive function and serum metabolic profiles in a scopolamine-induced AD model. This combination therapy may reduce tyrosine and methionine levels, enhancing cognitive function by mitigating known risk factors for AD. The study provides a foundation for developing other bioactive compounds in AD treatment.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Kuang-Hsing Chiang, Tain-Junn Cheng, Wei-Chih Kan, Hsien-Yi Wang, Jui-Chen Li, Yan-Ling Cai, Chia-Hui Cheng, Yi-Chien Liu, Chia-Yu Chang, Jiunn-Jye Chuu
Summary: The ethanolic extract of Orthosiphon aristatus (OA) demonstrated an improving effect on memory and could serve as a potential therapeutic target for the treatment of neurodegenerative diseases like Alzheimer's disease (AD).
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Meryem Tourabi, Asmae EL Ghouizi, Ghizlane Nouioura, Khaoula Faiz, Hind Elfatemi, Karima El-yagoubi, Badiaa Lyoussi, Elhoussine Derwich
Summary: Mentha longifolia is a native plant in Morocco, traditionally used to treat various diseases. This study analyzed the phytochemical profile of the aqueous extract of M. longifolia and evaluated its acute and subacute toxicity in mice. The results showed that M. longifolia extract is rich in phenolic compounds and has no observed toxicity up to a certain dosage limit.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Yue Zhang, Liang Li, Tao Chai, Han Xu, Hong-yan Du, Yan Jiang
Summary: Mulberry leaf multi-components (MMC) have hypoglycemic effects and can improve insulin resistance by activating the PI-3K/Akt signaling pathway. These findings highlight the multi-component, multi-target, and combined effects of MMC, and suggest it may be further developed as a hypoglycemic drug.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Correction
Plant Sciences
Shan Luo, Yuanchun Chen, Ruoxi Zhao, Donglai Ma, Yanmeng Zhao, Ying Zhang, Jianming Jiang, Wentao Yu
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Nittaya Chansiw, Pattranuch Chusri, Siwaporn Praman, Thaneeya Hawiset, Wannisa Sukhorum, Sorraya Champakam, Rawiwan Charoensup
Summary: This study evaluates the anti-inflammatory activity of Prabchompoothaweep (PCT) extract in an animal model. The results show that PCT significantly reduces inflammation and pro-inflammatory cytokines in acute and sub-acute inflammation. These findings suggest that PCT could be a new option for the treatment of inflammatory diseases.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Yanting Wang, Guoqiang Liang, Wei Mu, Shu Sun, Xuanyi Chen, Xiaofeng Xu
Summary: Bushen Tianjing Recipe (BTR) is a tonic-kidney formula of Traditional Chinese Medicine (TCM) with good therapeutic effects in clinical settings. The aim of this study was to investigate the effect of BTR on women's reproductive system by incubating miR-23a-induced KGN cells.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Jiayi Zhi, Li Yin, Zhoudong Zhang, Yaozhong Lv, Fan Wu, Yang Yang, Enming Zhang, Huanqiu Li, Ning Lu, Mengze Zhou, Qinghua Hu
Summary: This study verified the pharmacodynamics of JSW in the treatment of AD and explored its potential mechanism using network pharmacology, molecular docking, and experimental validation.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Review
Plant Sciences
Elizabeth Syowai Mutinda, Dong-Juan Zhang, Felix Wambua Muema, Elijah Mbandi Mkala, Emmanuel Nyongesa Waswa, Wyclif Ochieng Odago, Clintone Onyango Ochieng, Moses Kirega Gichua, John Kamau Muchuku, Elizabeth Kamande, Guang-Wan Hu
Summary: This article reviews the traditional uses, pharmacological properties, and phytoconstituents of Balanophora species, revealing that they contain diverse chemical compounds with interesting biological activities. However, research on many species in this genus is still lacking.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Luqi Cai, Yu Chen, Huizhong Xue, Yimeng Yang, Yuqi Wang, Junhe Xu, Chunyan Zhu, Long He, Yonghua Xiao
Summary: Salvia miltiorrhiza Bunge (SM) has been proven to have potential therapeutic effects for diabetic nephropathy (DN) through its multi-component, multi-target, and multi-pathway pharmacological effects.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)
Article
Plant Sciences
Chao Wang, Rui-Jia Fu, Ding-Qiao Xu, Qian Zuo, Ji-Ping Liu, Yu-Ping Tang
Summary: This study aimed to explore the hepatoprotective effects of Shicao on CCl4-induced acute liver injury. A rat model of acute liver injury was established and liver function indices were assessed. Untargeted metabolomics was conducted to identify differential metabolites. Network pharmacology was used to construct a network of metabolite-reaction-enzyme-gene constituents, and key components and hub genes were screened. Shicao showed hepatoprotective effects against acute liver injury in rats.
JOURNAL OF ETHNOPHARMACOLOGY
(2024)