Iron-catalyzed N-alkylation of aromatic amines via borrowing hydrogen strategy

Earth-abundant transition metals could be used as a noble metal replacement in catalysis not only for different catalytic reactivity but environmentally benign methodology. We report here on the iron-catalyzed synthesis of N-alkylated amines via borrowing hydrogen strategy and differently functionalized aniline derivatives are alkylated in good yields.

Automated summary

By using Earth-abundant transition metals such as iron as catalysts, N-alkylated amines can be synthesized via borrowing hydrogen strategy, resulting in alkylated aniline derivatives with different functional groups in good yields. This method is environmentally friendly and efficient.