Identification of MKRN1 as a second E3 ligase for Eag1 potassium channels reveals regulation via differential degradation

Ubiquitylation and degradation of adenomatous polyposis coli by MKRN1 enhances Wnt/β-catenin signaling

(2018) Hae-Kyung Lee et al.   ONCOGENE

Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation

(2018) Min-Sik Lee et al.   Nature Communications

Cullin 7 mediates proteasomal and lysosomal degradations of rat Eag1 potassium channels

(2017) Po-Hao Hsu et al.   Scientific Reports

PICK1/calcineurin suppress ASIC1-mediated Ca2+ entry in rat pulmonary arterial smooth muscle cells

(2016) Lindsay M. Herbert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Integrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network

(2015) P. A. Cassar et al.   EMBO REPORTS

‘Splitting versus lumping’: Temple–Baraitser and Zimmermann–Laband Syndromes

(2015) Nuria C. Bramswig et al.   HUMAN GENETICS

Mutations in KCNH1 and ATP6V1B2 cause Zimmermann-Laband syndrome

(2015) Fanny Kortüm et al.   NATURE GENETICS

RNF121 Inhibits Angiogenic Growth Factor Signaling by Restricting Cell Surface Expression of VEGFR-2

(2015) Armin Maghsoudlou et al.   TRAFFIC

PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis

(2015) Min-Sik Lee et al.   Nature Communications

Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy

(2014) Cas Simons et al.   NATURE GENETICS

Inhibition of post-translational N-glycosylation by HRD1 that controls the fate of ABCG5/8 transporter

(2014) Shingo Suzuki et al.   Scientific Reports

Behavioural and functional characterization of Kv10.1 (Eag1) knockout mice

(2013) Roser Ufartes et al.   HUMAN MOLECULAR GENETICS

Ubiquitin and Membrane Protein Turnover: From Cradle to Grave

(2012) Jason A. MacGurn et al.   Annual Review of Biochemistry

Kcnh1 Voltage-gated Potassium Channels Are Essential for Early Zebrafish Development

(2012) Rayk Stengel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acceleration of Gastric Tumorigenesis Through MKRN1-Mediated Posttranslational Regulation of p14ARF

(2012) Aram Ko et al.   JNCI-Journal of the National Cancer Institute

Mechanisms for quality control of misfolded transmembrane proteins

(2011) Scott A. Houck et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Makorin Ring Zinc Finger Protein 1 (MKRN1), a Novel Poly(A)-binding Protein-interacting Protein, Stimulates Translation in Nerve Cells

(2011) Hatmone Miroci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuronal trafficking of voltage-gated potassium channels

(2011) Camilla S. Jensen et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Eag 1, Eag 2 and Kcnn3 gene brain expression of isolated reared rats

(2010) S. Martin et al.   GENES BRAIN AND BEHAVIOR

Protein homeostasis and aging in neurodegeneration

(2010) Peter M. Douglas et al.   JOURNAL OF CELL BIOLOGY

Differentiation linked regulation of telomerase activity by Makorin-1

(2010) Jose Salvatico et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Homeostatic Regulation of Neuronal Excitability by K+ Channels in Normal and Diseased Brains

(2010) Hiroaki Misonou   NEUROSCIENTIST

The Proteome in Balance

(2010) D. Hutt et al.   SCIENCE

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

Identification of Makorin 1 as a novel SEREX antigen of esophageal squamous cell carcinoma

(2009) Hideaki Shimada et al.   BMC CANCER

Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis

(2009) Eun-Woo Lee et al.   EMBO JOURNAL

N-glycans are direct determinants of CFTR folding and stability in secretory and endocytic membrane traffic

(2009) Rina Glozman et al.   JOURNAL OF CELL BIOLOGY

MKRN1 Induces Degradation of West Nile Virus Capsid Protein by Functioning as an E3 Ligase

(2009) A. Ko et al.   JOURNAL OF VIROLOGY

Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay

(2008) Ola Söderberg et al.   METHODS

Eag1 potassium channel immunohistochemistry in the CNS of adult rat and selected regions of human brain

(2008) S. Martin et al.   NEUROSCIENCE